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Entry version 116 (29 Sep 2021)
Sequence version 1 (19 Jul 2004)
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Protein

Zinc finger protein 574

Gene

znf574

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri15 – 37C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri58 – 80C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri99 – 121C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri206 – 228C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri297 – 319C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri324 – 346C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri352 – 374C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri380 – 401C2H2-type 8PROSITE-ProRule annotationAdd BLAST22
Zinc fingeri428 – 451C2H2-type 9PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri457 – 479C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri485 – 507C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri513 – 535C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri541 – 563C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri569 – 591C2H2-type 14PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri597 – 619C2H2-type 15; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri628 – 651C2H2-type 16PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri681 – 703C2H2-type 17PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri709 – 731C2H2-type 18PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri737 – 759C2H2-type 19PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri765 – 787C2H2-type 20PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 574
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:znf574
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri8364 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000008143 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

Organism-specific databases

Xenopus laevis and tropicalis biology and genomics resource

More...
Xenbasei
XB-GENE-1004140, znf574

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002748661 – 857Zinc finger protein 574Add BLAST857

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q6GL52

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSXETG00000027536, Expressed in blastula and 11 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
8364.ENSXETP00000057402

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q6GL52

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni648 – 678DisorderedSequence analysisAdd BLAST31

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi648 – 665Polar residuesSequence analysisAdd BLAST18

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri15 – 37C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri58 – 80C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri99 – 121C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri206 – 228C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri297 – 319C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri324 – 346C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri352 – 374C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri380 – 401C2H2-type 8PROSITE-ProRule annotationAdd BLAST22
Zinc fingeri428 – 451C2H2-type 9PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri457 – 479C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri485 – 507C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri513 – 535C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri541 – 563C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri569 – 591C2H2-type 14PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri597 – 619C2H2-type 15; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri628 – 651C2H2-type 16PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri681 – 703C2H2-type 17PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri709 – 731C2H2-type 18PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri737 – 759C2H2-type 19PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri765 – 787C2H2-type 20PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1721, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000161799

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_002678_24_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q6GL52

Identification of Orthologs from Complete Genome Data

More...
OMAi
EDCAMEL

Database of Orthologous Groups

More...
OrthoDBi
1318335at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q6GL52

TreeFam database of animal gene trees

More...
TreeFami
TF350791

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00096, zf-C2H2, 7 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00355, ZnF_C2H2, 20 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57667, SSF57667, 10 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 18 hits
PS50157, ZINC_FINGER_C2H2_2, 19 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q6GL52-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTDSEETVLY VEHRYVCSEC GEEYPSLEEA LEHQQSHAAA LQEPQYQIVG
60 70 80 90 100
VNSLENQYQC LECGLLLRTP EDLLAHQELH PTQNEIQKPK RPTRSEIHYE
110 120 130 140 150
CPECKALFNS QDVWMAHRYT HMQVQDVSHS KIVLQTDDHV IEDGLQLMCA
160 170 180 190 200
PAVPSEVHLV TGDPHFHVST PSSASVSHTQ VLVDLEHSYK KNEGAGEDCA
210 220 230 240 250
MELLLYKCSE CTQLFQTPGE FLEHQGTHFS GQERISDTNS HLDQTPQLSL
260 270 280 290 300
NGQEKEPIIN QGNTCTDYQA ENKELLVQPE GEQAEQDSWT VDREPVFSCG
310 320 330 340 350
DCSETFQTTK DLEEHQISHQ NGPFSCPLCS KVFPTYPEVG EHLKSHRSES
360 370 380 390 400
RYLCVDCGLA FVSEAVLLNH RRSHLANPLF TCECGLTFLN MTRFLYHRRV
410 420 430 440 450
HSSKQPDTGA VEEKKTVNSI APSPAGNFHC DPCGKDFPLL SQFLRHQRFV
460 470 480 490 500
HALERRHKCP TCGKHFKKGS HLRTHMLTHT GERPYSCTVC SKSFNSQANL
510 520 530 540 550
LRHRLTHTGE KPYKCQLCGK AFSQSSTLQQ HQYVHGQAYL YKCNECGINF
560 570 580 590 600
HRPYRLLLHQ YHHTGEYPYK CQDCGLSFLL KRLLEVHQLG HRGEEPHRCR
610 620 630 640 650
ECGTNFPSVQ RLQDHRCSKA GDGGGEKLEC PICGKKVTSD AHLNTHVAAQ
660 670 680 690 700
HSGNKRSNVS SGKGTPVLPR NKLKGGGGKN LECSDCHKTF STETSLQVHR
710 720 730 740 750
RIHTGERPYP CPDCGKAFRQ STHLKDHRRL HTGEKPFKCD VCGKAFTIAV
760 770 780 790 800
RLSEHKRIHT GERPHSCPDC GRAYRSFSNL WKHRKLHREQ QVQLQEPESQ
810 820 830 840 850
PADLSSTVAI LETVETIPII ETVEIFPEGS TISVQDIQFE TLQVENIHLG

NIQIGTL
Length:857
Mass (Da):97,090
Last modified:July 19, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB9F27F36B7DC3618
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A6I8RY83A0A6I8RY83_XENTR
Zinc finger protein 574
znf574
877Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BC074658 mRNA Translation: AAH74658.1

NCBI Reference Sequences

More...
RefSeqi
NP_001004843.1, NM_001004843.1
XP_012821811.1, XM_012966357.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSXETT00000057402; ENSXETP00000057402; ENSXETG00000027536
ENSXETT00000091090; ENSXETP00000090223; ENSXETG00000027536
ENSXETT00000111198; ENSXETP00000119299; ENSXETG00000027536

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
448126

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
xtr:448126

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC074658 mRNA Translation: AAH74658.1
RefSeqiNP_001004843.1, NM_001004843.1
XP_012821811.1, XM_012966357.2

3D structure databases

SMRiQ6GL52
ModBaseiSearch...

Protein-protein interaction databases

STRINGi8364.ENSXETP00000057402

Proteomic databases

PaxDbiQ6GL52

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
448126

Genome annotation databases

EnsembliENSXETT00000057402; ENSXETP00000057402; ENSXETG00000027536
ENSXETT00000091090; ENSXETP00000090223; ENSXETG00000027536
ENSXETT00000111198; ENSXETP00000119299; ENSXETG00000027536
GeneIDi448126
KEGGixtr:448126

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
64763
XenbaseiXB-GENE-1004140, znf574

Phylogenomic databases

eggNOGiKOG1721, Eukaryota
GeneTreeiENSGT00940000161799
HOGENOMiCLU_002678_24_1_1
InParanoidiQ6GL52
OMAiEDCAMEL
OrthoDBi1318335at2759
PhylomeDBiQ6GL52
TreeFamiTF350791

Gene expression databases

BgeeiENSXETG00000027536, Expressed in blastula and 11 other tissues

Family and domain databases

InterProiView protein in InterPro
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
PfamiView protein in Pfam
PF00096, zf-C2H2, 7 hits
SMARTiView protein in SMART
SM00355, ZnF_C2H2, 20 hits
SUPFAMiSSF57667, SSF57667, 10 hits
PROSITEiView protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 18 hits
PS50157, ZINC_FINGER_C2H2_2, 19 hits

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN574_XENTR
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6GL52
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: July 19, 2004
Last modified: September 29, 2021
This is version 116 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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