UniProtKB - Q6G409 (KDSA_BARHE)
Protein
2-dehydro-3-deoxyphosphooctonate aldolase
Gene
kdsA
Organism
Bartonella henselae (strain ATCC 49882 / DSM 28221 / Houston 1) (Rochalimaea henselae)
Status
Functioni
Catalytic activityi
- D-arabinose 5-phosphate + H2O + phosphoenolpyruvate = 3-deoxy-α-D-manno-2-octulosonate-8-phosphate + phosphateUniRule annotationEC:2.5.1.55UniRule annotation
: 3-deoxy-D-manno-octulosonate biosynthesis Pathwayi
This protein is involved in step 2 of the subpathway that synthesizes 3-deoxy-D-manno-octulosonate from D-ribulose 5-phosphate.UniRule annotationProteins known to be involved in the 3 steps of the subpathway in this organism are:
- no protein annotated in this organism
- 2-dehydro-3-deoxyphosphooctonate aldolase (kdsA)
- no protein annotated in this organism
View all proteins of this organism that are known to be involved in the subpathway that synthesizes 3-deoxy-D-manno-octulosonate from D-ribulose 5-phosphate, the pathway 3-deoxy-D-manno-octulosonate biosynthesis and in Carbohydrate biosynthesis.
Pathwayi: lipopolysaccharide biosynthesis
This protein is involved in the pathway lipopolysaccharide biosynthesis, which is part of Bacterial outer membrane biogenesis.UniRule annotationView all proteins of this organism that are known to be involved in the pathway lipopolysaccharide biosynthesis and in Bacterial outer membrane biogenesis.
GO - Molecular functioni
- 3-deoxy-8-phosphooctulonate synthase activity Source: UniProtKB-UniRule
GO - Biological processi
- keto-3-deoxy-D-manno-octulosonic acid biosynthetic process Source: UniProtKB-UniRule
Keywordsi
Molecular function | Transferase |
Biological process | Lipopolysaccharide biosynthesis |
Enzyme and pathway databases
BioCyci | BHEN283166:G1GJ7-592-MONOMER |
UniPathwayi | UPA00030 UPA00357;UER00474 |
Names & Taxonomyi
Protein namesi | Recommended name: 2-dehydro-3-deoxyphosphooctonate aldolaseUniRule annotation (EC:2.5.1.55UniRule annotation)Alternative name(s): 3-deoxy-D-manno-octulosonic acid 8-phosphate synthaseUniRule annotation KDO-8-phosphate synthaseUniRule annotation Short name: KDO 8-P synthaseUniRule annotation Short name: KDOPSUniRule annotation Phospho-2-dehydro-3-deoxyoctonate aldolaseUniRule annotation |
Gene namesi | Name:kdsAUniRule annotation Ordered Locus Names:BH05710 |
Organismi | Bartonella henselae (strain ATCC 49882 / DSM 28221 / Houston 1) (Rochalimaea henselae) |
Taxonomic identifieri | 283166 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bartonellaceae › Bartonella › |
Proteomesi |
|
Subcellular locationi
- Cytoplasm UniRule annotation
GO - Cellular componenti
- cytoplasm Source: UniProtKB-SubCell
Keywords - Cellular componenti
CytoplasmPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000187100 | 1 – 279 | 2-dehydro-3-deoxyphosphooctonate aldolaseAdd BLAST | 279 |
Proteomic databases
PaxDbi | Q6G409 |
PRIDEi | Q6G409 |
Family & Domainsi
Sequence similaritiesi
Belongs to the KdsA family.UniRule annotation
Phylogenomic databases
eggNOGi | COG2877, Bacteria |
OMAi | FRGIPTM |
Family and domain databases
Gene3Di | 3.20.20.70, 1 hit |
HAMAPi | MF_00056, KDO8P_synth, 1 hit |
InterProi | View protein in InterPro IPR013785, Aldolase_TIM IPR006218, DAHP1/KDSA IPR006269, KDO8P_synthase |
PANTHERi | PTHR21057, PTHR21057, 1 hit |
Pfami | View protein in Pfam PF00793, DAHP_synth_1, 1 hit |
TIGRFAMsi | TIGR01362, KDO8P_synth, 1 hit |
i Sequence
Sequence statusi: Complete.
Q6G409-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSEPNAIVKV GNIIFSNEAP FSLIAGPCQI ESRDHAFEMA GRIKTITDQV
60 70 80 90 100
GIGFVYKSSY DKANRTSLSA VRGVGLENAM AIFSDLKKEF GCPILTDVHT
110 120 130 140 150
EEQCTVVAST VDILQIPAFL CRQTDLLVAA AKTGRVINIK KGQFLAPWDM
160 170 180 190 200
KNVLRKVTQS GNRNVMLCER GTSFGYNRLI SDMRSLPILR SFGAPVIFDA
210 220 230 240 250
THSVQEPGGQ GDSSGGQRQF VEILARAAVS VGVAGIFLET HQDPDNAPSD
260 270
GPNMIKIDHL QRLLETLMEF DYLSKKTIE
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX897699 Genomic DNA Translation: CAF27379.1 |
RefSeqi | WP_011180500.1, NZ_LRIJ02000001.1 |
Genome annotation databases
EnsemblBacteriai | CAF27379; CAF27379; BH05710 |
GeneIDi | 29621777 |
KEGGi | bhe:BH05710 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX897699 Genomic DNA Translation: CAF27379.1 |
RefSeqi | WP_011180500.1, NZ_LRIJ02000001.1 |
3D structure databases
SMRi | Q6G409 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 283166.BH05710 |
Proteomic databases
PaxDbi | Q6G409 |
PRIDEi | Q6G409 |
Genome annotation databases
EnsemblBacteriai | CAF27379; CAF27379; BH05710 |
GeneIDi | 29621777 |
KEGGi | bhe:BH05710 |
Phylogenomic databases
eggNOGi | COG2877, Bacteria |
OMAi | FRGIPTM |
Enzyme and pathway databases
UniPathwayi | UPA00030 UPA00357;UER00474 |
BioCyci | BHEN283166:G1GJ7-592-MONOMER |
Family and domain databases
Gene3Di | 3.20.20.70, 1 hit |
HAMAPi | MF_00056, KDO8P_synth, 1 hit |
InterProi | View protein in InterPro IPR013785, Aldolase_TIM IPR006218, DAHP1/KDSA IPR006269, KDO8P_synthase |
PANTHERi | PTHR21057, PTHR21057, 1 hit |
Pfami | View protein in Pfam PF00793, DAHP_synth_1, 1 hit |
TIGRFAMsi | TIGR01362, KDO8P_synth, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | KDSA_BARHE | |
Accessioni | Q6G409Primary (citable) accession number: Q6G409 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 15, 2005 |
Last sequence update: | July 19, 2004 | |
Last modified: | December 2, 2020 | |
This is version 89 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Documents
- PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families