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Protein

Phosphoglycerate mutase

Gene

GPM1

Organism
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

2-phospho-D-glycerate = 3-phospho-D-glycerate.UniRule annotation

Pathwayi: glycolysis

This protein is involved in step 3 of the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate.UniRule annotation
Proteins known to be involved in the 5 steps of the subpathway in this organism are:
  1. Glyceraldehyde-3-phosphate dehydrogenase 1 (GPD1), Glyceraldehyde-3-phosphate dehydrogenase 2 (GPD2)
  2. Phosphoglycerate kinase (PGK1)
  3. Phosphoglycerate mutase (GPM1), Phosphoglycerate mutase (CAGL0K01705g)
  4. Enolase 1 (ENO1), Enolase 2 (ENO2)
  5. Pyruvate kinase 2 (PYK2), Pyruvate kinase 1 (PYK1)
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate, the pathway glycolysis and in Carbohydrate degradation.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotation
Biological processGlycolysisUniRule annotation

Enzyme and pathway databases

UniPathwayiUPA00109; UER00186

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate mutaseUniRule annotation (EC:5.4.2.11UniRule annotation)
Gene namesi
Name:GPM1Imported
Ordered Locus Names:CAGL0E06358gImported
OrganismiCandida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)Imported
Taxonomic identifieri284593 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeNakaseomycesNakaseomyces/Candida clade
Proteomesi
  • UP000002428 Componenti: Chromosome E

Organism-specific databases

CGDiCAL0129130 GPM1
EuPathDBiFungiDB:CAGL0E06358g

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Interactioni

Protein-protein interaction databases

STRINGi284593.XP_445966.1

Structurei

3D structure databases

ProteinModelPortaliQ6FUX8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.UniRule annotation

Phylogenomic databases

eggNOGiKOG0235 Eukaryota
COG0588 LUCA
HOGENOMiHOG000221682
InParanoidiQ6FUX8
KOiK01834
OMAiRMLPYWY
OrthoDBiEOG092C4JJL

Family and domain databases

CDDicd07067 HP_PGM_like, 1 hit
Gene3Di3.40.50.1240, 1 hit
HAMAPiMF_01039 PGAM_GpmA, 1 hit
InterProiView protein in InterPro
IPR013078 His_Pase_superF_clade-1
IPR029033 His_PPase_superfam
IPR001345 PG/BPGM_mutase_AS
IPR005952 Phosphogly_mut1
PANTHERiPTHR11931 PTHR11931, 1 hit
PfamiView protein in Pfam
PF00300 His_Phos_1, 2 hits
SMARTiView protein in SMART
SM00855 PGAM, 1 hit
SUPFAMiSSF53254 SSF53254, 1 hit
TIGRFAMsiTIGR01258 pgm_1, 1 hit
PROSITEiView protein in PROSITE
PS00175 PG_MUTASE, 1 hit

Sequencei

Sequence statusi: Complete.

Q6FUX8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPKLVLVRHG QSEWNEKNLF TGWVDVRLSA KGEQEAARAG ELLKEKNVHP
60 70 80 90 100
DILYTSKLSR AIQTANIALS KADRLWIPVK RSWRLNERHY GALQGKDKAE
110 120 130 140 150
TLETYGEEKF NTWRRSFDVP PPVIEADSPY SQKNDERYRD VDPNVLPQTE
160 170 180 190 200
SLALVIDRLL PYWEDVIAKD LLAGKTVMIA AHGNSLRGLV KHLEGISDAD
210 220 230 240
IAKLNIPTGI PLVFELDENL KPSKPSYYLD PEAAAAGAAA VAAQGKK
Length:247
Mass (Da):27,590
Last modified:July 19, 2004 - v1
Checksum:i3A8975790206941B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR380951 Genomic DNA Translation: CAG58885.1
RefSeqiXP_445966.1, XM_445966.1

Genome annotation databases

EnsemblFungiiCAG58885; CAG58885; CAGL0E06358g
GeneIDi2887384
KEGGicgr:CAGL0E06358g

Similar proteinsi

Entry informationi

Entry nameiQ6FUX8_CANGA
AccessioniPrimary (citable) accession number: Q6FUX8
Entry historyiIntegrated into UniProtKB/TrEMBL: July 19, 2004
Last sequence update: July 19, 2004
Last modified: September 27, 2017
This is version 93 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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