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Protein

Protein-S-isoprenylcysteine O-methyltransferase

Gene

CAGL0F02805g

Organism
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + protein C-terminal S-farnesyl-L-cysteine = S-adenosyl-L-homocysteine + protein C-terminal S-farnesyl-L-cysteine methyl ester.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferaseUniRule annotation, Transferase
LigandS-adenosyl-L-methionineUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Protein-S-isoprenylcysteine O-methyltransferaseUniRule annotation (EC:2.1.1.100UniRule annotation)
Gene namesi
Ordered Locus Names:CAGL0F02805gImported
OrganismiCandida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)Imported
Taxonomic identifieri284593 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeNakaseomycesNakaseomyces/Candida clade
Proteomesi
  • UP000002428 Componenti: Chromosome F

Organism-specific databases

CGDiCAL0131202 CAGL0F02805g
EuPathDBiFungiDB:CAGL0F02805g

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei37 – 56HelicalUniRule annotationAdd BLAST20
Transmembranei63 – 80HelicalUniRule annotationAdd BLAST18
Transmembranei100 – 119HelicalUniRule annotationAdd BLAST20
Transmembranei131 – 149HelicalUniRule annotationAdd BLAST19
Transmembranei192 – 220HelicalUniRule annotationAdd BLAST29

Keywords - Cellular componenti

Endoplasmic reticulumUniRule annotation, Membrane

Interactioni

Protein-protein interaction databases

STRINGi284593.XP_446092.1

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG2628 Eukaryota
COG2020 LUCA
HOGENOMiHOG000213961
InParanoidiQ6FUK2
KOiK00587
OMAiFRTIAMY
OrthoDBiEOG092C5DVA

Family and domain databases

InterProiView protein in InterPro
IPR007269 ICMT_MeTrfase
IPR025770 PPMT_MeTrfase
PfamiView protein in Pfam
PF04140 ICMT, 1 hit
PROSITEiView protein in PROSITE
PS51564 SAM_ICMT, 1 hit

Sequencei

Sequence statusi: Complete.

Q6FUK2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTGSNKSEKF VPDAEGLPVI INGKAYPDIR RNPLDDIAVT SFALGILLGI
60 70 80 90 100
FVGLLTFTQF RNFNVYIIAL SIFHFLEFYV TAKVNPGKVN SDSFLLNNGI
110 120 130 140 150
GYLGAHMFGV LECLVESIFF PNMKKISNSW VAIFLTIIGV ILILLGQVSR
160 170 180 190 200
SMAMYQAGKS FSHILKTEKL DDHTLVTTGI YGYLRHPSYF GFFWWAIGTQ
210 220 230 240 250
LLLLNPIALI VFVGVLWSFF NKRILIEEKY LIQFFGEQYI NYKKRVKVWI

PLID
Length:254
Mass (Da):28,885
Last modified:July 19, 2004 - v1
Checksum:iBD4DBC705FC8F95C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR380952 Genomic DNA Translation: CAG59016.1
RefSeqiXP_446092.1, XM_446092.1

Genome annotation databases

EnsemblFungiiCAG59016; CAG59016; CAGL0F02805g
GeneIDi2887597
KEGGicgr:CAGL0F02805g

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR380952 Genomic DNA Translation: CAG59016.1
RefSeqiXP_446092.1, XM_446092.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi284593.XP_446092.1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCAG59016; CAG59016; CAGL0F02805g
GeneIDi2887597
KEGGicgr:CAGL0F02805g

Organism-specific databases

CGDiCAL0131202 CAGL0F02805g
EuPathDBiFungiDB:CAGL0F02805g

Phylogenomic databases

eggNOGiKOG2628 Eukaryota
COG2020 LUCA
HOGENOMiHOG000213961
InParanoidiQ6FUK2
KOiK00587
OMAiFRTIAMY
OrthoDBiEOG092C5DVA

Family and domain databases

InterProiView protein in InterPro
IPR007269 ICMT_MeTrfase
IPR025770 PPMT_MeTrfase
PfamiView protein in Pfam
PF04140 ICMT, 1 hit
PROSITEiView protein in PROSITE
PS51564 SAM_ICMT, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ6FUK2_CANGA
AccessioniPrimary (citable) accession number: Q6FUK2
Entry historyiIntegrated into UniProtKB/TrEMBL: July 19, 2004
Last sequence update: July 19, 2004
Last modified: September 27, 2017
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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