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Entry version 98 (07 Oct 2020)
Sequence version 1 (19 Jul 2004)
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Protein

Importin N-terminal domain-containing protein

Gene

CAGL0G03443g

Organism
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processProtein transportARBA annotation, Transport

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Importin N-terminal domain-containing proteinInterPro annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:CAGL0G03443gImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCandida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri284593 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeNakaseomycesNakaseomyces/Candida clade
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002428 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome G

Organism-specific databases

Candida Genome Database

More...
CGDi
CAL0137765, CAGL0G03443g

Eukaryotic Pathogen Database Resources

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EuPathDBi
FungiDB:CAGL0G03443g

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

CytoplasmARBA annotation

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
5478.XP_446513.1

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini27 – 94Importin N-terminalInterPro annotationAdd BLAST68
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati400 – 438HEATPROSITE-ProRule annotationAdd BLAST39

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2171, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_003794_1_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q6FTD1

KEGG Orthology (KO)

More...
KOi
K20221

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016024, ARM-type_fold
IPR021133, HEAT_type_2
IPR001494, Importin-beta_N
IPR040122, Importin_beta

The PANTHER Classification System

More...
PANTHERi
PTHR10527, PTHR10527, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03810, IBN_N, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00913, IBN_N, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371, SSF48371, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50077, HEAT_REPEAT, 1 hit
PS50166, IMPORTIN_B_NT, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q6FTD1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDQQFISQLE QALAAVTQPN SAGLKEATKT LQKQFYTQPN SVAALVHILH
60 70 80 90 100
HSNDDALKQL AGVEVRKLIP KHWASIDVAT KNGIKETVLQ YAFSEQKEII
110 120 130 140 150
RHSNARVIAV IGSEEMSDNQ WPELIPNLVQ AAAGEDSKTR ETAVFILLSL
160 170 180 190 200
LEDFDSSLVS YIDDFLTLFS QTINDTTSLE TRSLSAQALN HVSALIEEQE
210 220 230 240 250
EINPQQAARF AAMIPSVVSV LEAVIKADDV PNTKQIFNCL NDFLLLDSQL
260 270 280 290 300
TGNAIVDLIK LALQVAINTE IDEDVRVYAT QFIISALSCR KSKIIQAKLG
310 320 330 340 350
PEITLTALKI AAEEIDVQDE LNNEDEAGEN EENTPSMVAI RLLAFASTEL
360 370 380 390 400
PPSQVAAVII EHLPTMLNSQ NVFERRAILL AISVVVTGSP DYILSQFDKV
410 420 430 440 450
IPATISGLKD NEQVVKLAAL KCVHNLTTDL QDEVAKFHED YLPLIIDIID
460 470 480 490 500
NAGTVVIYNY ATVALDGILE FIAYEAIAKY LEPLMNKLFH MLSTSNSSKL
510 520 530 540 550
KCAVVSAIGS AAFAAGLAFV PYFKTSVQYL EQFIQNCSQI EGMSEDDIEL
560 570 580 590 600
RANTFENIST MARAVRSENF APFAEPLVNS AYEAIKTDSA RLRESGYAFI
610 620 630 640 650
ANLAKVYGEN FSPFLETILP EIFKTLELDE YQFNFDGDAD ELAALADGAT
660 670 680 690 700
EEELQSKFTV NTGISYEKEV AAAALSELAL GTKEHFLPYV EQSLKVLNQQ
710 720 730 740 750
VDESYGLRES ALNTIWNIIK AVLLASKVQQ DEYPKGFPAA SYVDPSVLAV
760 770 780 790 800
IQTARETTLS YLENEFETSM VITILEDFAN MIKLFGPIII MDNGNSSHLE
810 820 830 840 850
NLCLQVSSVL ENKHTCQVAD LEEDIPRDED LDASETEATL LDVALEVLVS
860 870 880 890 900
LAVALGPDFA KVFEPFKTTL LTLCQSKSKN KRSSAVGAAS EIALGMKEQN
910 920 930 940 950
PYIHEMLEAL VIRLTSDKSL EVRGNAAYGV GLLCEYAPFD VSQVYEHVLK
960 970 980 990 1000
ALYQLLSVAD EKAADDDEAT REIIDRAFAN ASGCVARMAL KHQNLIPLEQ
1010 1020 1030 1040 1050
TLPALLSHLP LKTGFEEYDP IFKLIMQLYE SNNEVISGLT PNVVELFGHV
1060 1070 1080 1090 1100
FTMENERLKL ERESTLGREE NMERLRQFQS EDVRVKVVEL LKYLNSKYNG
1110
VVAQNQVLAP VIA
Length:1,113
Mass (Da):123,038
Last modified:July 19, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iBB7ADFF84E86FDDF
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CR380953 Genomic DNA Translation: CAG59440.1

NCBI Reference Sequences

More...
RefSeqi
XP_446513.1, XM_446513.1

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
CAG59440; CAG59440; CAGL0G03443g

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
2888192

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cgr:CAGL0G03443g

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR380953 Genomic DNA Translation: CAG59440.1
RefSeqiXP_446513.1, XM_446513.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi5478.XP_446513.1

Genome annotation databases

EnsemblFungiiCAG59440; CAG59440; CAGL0G03443g
GeneIDi2888192
KEGGicgr:CAGL0G03443g

Organism-specific databases

CGDiCAL0137765, CAGL0G03443g
EuPathDBiFungiDB:CAGL0G03443g

Phylogenomic databases

eggNOGiKOG2171, Eukaryota
HOGENOMiCLU_003794_1_1_1
InParanoidiQ6FTD1
KOiK20221

Family and domain databases

InterProiView protein in InterPro
IPR016024, ARM-type_fold
IPR021133, HEAT_type_2
IPR001494, Importin-beta_N
IPR040122, Importin_beta
PANTHERiPTHR10527, PTHR10527, 1 hit
PfamiView protein in Pfam
PF03810, IBN_N, 1 hit
SMARTiView protein in SMART
SM00913, IBN_N, 1 hit
SUPFAMiSSF48371, SSF48371, 2 hits
PROSITEiView protein in PROSITE
PS50077, HEAT_REPEAT, 1 hit
PS50166, IMPORTIN_B_NT, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ6FTD1_CANGA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6FTD1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 19, 2004
Last sequence update: July 19, 2004
Last modified: October 7, 2020
This is version 98 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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Main funding by: National Institutes of Health

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