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Protein

26S proteasome regulatory subunit RPN1

Gene

RPN1

Organism
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.By similarity

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
26S proteasome regulatory subunit RPN1
Gene namesi
Name:RPN1
Ordered Locus Names:CAGL0J00605g
OrganismiCandida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)
Taxonomic identifieri284593 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeNakaseomycesNakaseomyces/Candida clade
Proteomesi
  • UP000002428 Componenti: Chromosome J

Organism-specific databases

CGDiCAL0133686 CAGL0J00605g
EuPathDBiFungiDB:CAGL0J00605g

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Proteasome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001738121 – 98326S proteasome regulatory subunit RPN1Add BLAST983

Proteomic databases

PRIDEiQ6FPV6

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi284593.XP_447738.1

Structurei

3D structure databases

ProteinModelPortaliQ6FPV6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati415 – 447PC 1Add BLAST33
Repeati448 – 484PC 2Add BLAST37
Repeati485 – 519PC 3Add BLAST35
Repeati520 – 557PC 4Add BLAST38
Repeati563 – 595PC 5Add BLAST33
Repeati768 – 799PC 6Add BLAST32
Repeati800 – 834PC 7Add BLAST35

Sequence similaritiesi

Belongs to the proteasome subunit S2 family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiKOG2005 Eukaryota
COG5110 LUCA
HOGENOMiHOG000176022
InParanoidiQ6FPV6
KOiK03028
OMAiMVDICAY
OrthoDBiEOG092C0RGR

Family and domain databases

Gene3Di1.25.10.10, 2 hits
InterProiView protein in InterPro
IPR016643 26S_Psome_Rpn1
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR002015 Proteasome/cyclosome_rpt
PANTHERiPTHR10943:SF1 PTHR10943:SF1, 1 hit
PfamiView protein in Pfam
PF01851 PC_rep, 1 hit
PIRSFiPIRSF015965 26S_Psome_Rpn1, 1 hit
SUPFAMiSSF48371 SSF48371, 5 hits

Sequencei

Sequence statusi: Complete.

Q6FPV6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSTDKKKEEV PKPETEDLTV KDETKNKDKK KANEEEELSE EDQKLKGDLE
60 70 80 90 100
MLVQTLLEDD SKLYETTLTQ LKEFIKNSTS SMTAVPKPLK FLRPFYPDLC
110 120 130 140 150
KAYDKWSDKD QKSSLADMLS VLAMTYSDTH QHDSLRFRLL SDTSNIASWG
160 170 180 190 200
HEYVRHLALE IGEVYNEQVE KEAEDNSTST ESSPQPPHMN FEFSKDVILQ
210 220 230 240 250
LSLEIVPYFM KHNGEEDAVD LLLEIEAIEK LPQFVDENTY KRVCQYMIAC
260 270 280 290 300
VQLLPPPEDI SFLQTAYSIY LSELQLPEAL SLAIRLGNED MIRSVFDATS
310 320 330 340 350
DPIVHQQLAY ILAAQRVPFE HPELQEIIGN TKLSEHFLYL AKELNLLTPK
360 370 380 390 400
IPEDIYKSHL DSSKSVFSSA GLDSAQQNLA ASFVNAFLNL GYCNDKMITD
410 420 430 440 450
NDNWVYKTKG DGMTSAVASI GSIYQWNIDG LQQLDKYLYV DEPEVKAGGL
460 470 480 490 500
LGIGIASAGV HHDVEPALLL LQEYINHSDT KISTAAILGI GIAFAGSKND
510 520 530 540 550
EVLGLLLPVV SNTENSLELA AIAALALSHV FVGTCNGDIT TAVMDNFLER
560 570 580 590 600
TPLELKSEWA RFLALSLGLL YLGQGEHVDD VLETINAIEH PMTSAIEVLI
610 620 630 640 650
SSCAYTATGD VLLVQDLLHR LTPKAVKSSD EDEDEDNEEL SQEDMNGISA
660 670 680 690 700
FLGKKENEIA EEPQGNEGAD NEMEVDSHQD ETTTGENNVK KEENEEEKTE
710 720 730 740 750
KSEKTENDEE EEDEEESKDE GANDELAYAV IGIALITMGE EIGKEMSLRH
760 770 780 790 800
FGHLMHYGNE HIRRMVPLAM GLVSVADPQM KVFDTLTRFS HDPDLDVSMN
810 820 830 840 850
SIFAMGLCGV GTNNARLAQL LRQLASYYSR EQDALFITRL AQGLVHLGKG
860 870 880 890 900
TMTMDIFNDA HVLNKVTLAS LLTVLVGLIS PSFILKHHQL FYMLNSGVRP
910 920 930 940 950
KFIITLNEEG EQIKVNVRIG QAVETVGQAG KPKTITGWIT QSTPVLLGHG
960 970 980
ERAELENDEY ISYTNNIEGV VILKKNPNFQ EEE
Length:983
Mass (Da):109,675
Last modified:July 19, 2004 - v1
Checksum:i5AA3CD4678085013
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR380956 Genomic DNA Translation: CAG60685.1
RefSeqiXP_447738.1, XM_447738.1

Genome annotation databases

EnsemblFungiiCAG60685; CAG60685; CAGL0J00605g
GeneIDi2889882
KEGGicgr:CAGL0J00605g

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR380956 Genomic DNA Translation: CAG60685.1
RefSeqiXP_447738.1, XM_447738.1

3D structure databases

ProteinModelPortaliQ6FPV6
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi284593.XP_447738.1

Proteomic databases

PRIDEiQ6FPV6

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCAG60685; CAG60685; CAGL0J00605g
GeneIDi2889882
KEGGicgr:CAGL0J00605g

Organism-specific databases

CGDiCAL0133686 CAGL0J00605g
EuPathDBiFungiDB:CAGL0J00605g

Phylogenomic databases

eggNOGiKOG2005 Eukaryota
COG5110 LUCA
HOGENOMiHOG000176022
InParanoidiQ6FPV6
KOiK03028
OMAiMVDICAY
OrthoDBiEOG092C0RGR

Family and domain databases

Gene3Di1.25.10.10, 2 hits
InterProiView protein in InterPro
IPR016643 26S_Psome_Rpn1
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR002015 Proteasome/cyclosome_rpt
PANTHERiPTHR10943:SF1 PTHR10943:SF1, 1 hit
PfamiView protein in Pfam
PF01851 PC_rep, 1 hit
PIRSFiPIRSF015965 26S_Psome_Rpn1, 1 hit
SUPFAMiSSF48371 SSF48371, 5 hits
ProtoNetiSearch...

Entry informationi

Entry nameiRPN1_CANGA
AccessioniPrimary (citable) accession number: Q6FPV6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 31, 2004
Last sequence update: July 19, 2004
Last modified: May 23, 2018
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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