UniProtKB - Q6FMP9 (Q6FMP9_CANGA)
Protein
Thioredoxin domain-containing protein
Gene
TSA1
Organism
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)
Status
Functioni
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.UniRule annotation
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 48 | Cysteine sulfenic acid (-SOH) intermediateUniRule annotation | 1 |
GO - Molecular functioni
- peroxidase activity Source: UniProtKB-UniRule
- peroxiredoxin activity Source: InterPro
Keywordsi
Molecular function | AntioxidantUniRule annotation, Oxidoreductase, PeroxidaseUniRule annotation |
Protein family/group databases
PeroxiBasei | 4469, Cgl2CysPrx02 |
Names & Taxonomyi
Protein namesi | Recommended name: Thioredoxin domain-containing proteinInterPro annotation |
Gene namesi | Name:TSA1Imported Ordered Locus Names:CAGL0K06259gImported |
Organismi | Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)Imported |
Taxonomic identifieri | 284593 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Nakaseomyces › Nakaseomyces/Candida clade › |
Proteomesi |
|
Organism-specific databases
CGDi | CAL0134717, TSA1 |
VEuPathDBi | FungiDB:CAGL0K06259g |
Subcellular locationi
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 34 – 55 | HelicalSequence analysisAdd BLAST | 22 |
Keywords - Cellular componenti
MembraneFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 3 – 161 | ThioredoxinInterPro annotationAdd BLAST | 159 |
Sequence similaritiesi
Belongs to the peroxiredoxin family.UniRule annotation
Keywords - Domaini
Redox-active centerUniRule annotation, Transmembrane, Transmembrane helixSequence analysisPhylogenomic databases
eggNOGi | KOG0852, Eukaryota |
HOGENOMi | CLU_042529_21_0_1 |
InParanoidi | Q6FMP9 |
OMAi | FWYPKDF |
Family and domain databases
Gene3Di | 3.40.30.10, 1 hit |
InterProi | View protein in InterPro IPR000866, AhpC/TSA IPR024706, Peroxiredoxin_AhpC-typ IPR019479, Peroxiredoxin_C IPR036249, Thioredoxin-like_sf IPR013766, Thioredoxin_domain |
Pfami | View protein in Pfam PF10417, 1-cysPrx_C, 1 hit PF00578, AhpC-TSA, 1 hit |
PIRSFi | PIRSF000239, AHPC, 1 hit |
SUPFAMi | SSF52833, SSF52833, 1 hit |
PROSITEi | View protein in PROSITE PS51352, THIOREDOXIN_2, 1 hit |
i Sequence
Sequence statusi: Complete.
Q6FMP9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MVAQVQKPAP TFKKTAVIDG MFEEVSLDKY KGKYVVLAFV PLAFTFVCPT
60 70 80 90 100
EIVAFSEAAK RFEALDAQVL FASTDSEYSL LAWTNVARKD GGLGPVDIPL
110 120 130 140 150
LADTNHKLSR DYGVLIEDEG IALRGLFIID PKGIVRHITI NDLPVGRNVE
160 170 180 190
ESLRLVEGFQ WTDKNGTVLP CNWTPGSATI KPTVEDSKEY FKEANSKN
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CR380957 Genomic DNA Translation: CAG61456.1 |
RefSeqi | XP_448495.1, XM_448495.1 |
Genome annotation databases
EnsemblFungii | CAG61456; CAG61456; CAGL0K06259g |
GeneIDi | 2890460 |
KEGGi | cgr:CAGL0K06259g |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CR380957 Genomic DNA Translation: CAG61456.1 |
RefSeqi | XP_448495.1, XM_448495.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 5478.XP_448495.1 |
Protein family/group databases
PeroxiBasei | 4469, Cgl2CysPrx02 |
Genome annotation databases
EnsemblFungii | CAG61456; CAG61456; CAGL0K06259g |
GeneIDi | 2890460 |
KEGGi | cgr:CAGL0K06259g |
Organism-specific databases
CGDi | CAL0134717, TSA1 |
VEuPathDBi | FungiDB:CAGL0K06259g |
Phylogenomic databases
eggNOGi | KOG0852, Eukaryota |
HOGENOMi | CLU_042529_21_0_1 |
InParanoidi | Q6FMP9 |
OMAi | FWYPKDF |
Family and domain databases
Gene3Di | 3.40.30.10, 1 hit |
InterProi | View protein in InterPro IPR000866, AhpC/TSA IPR024706, Peroxiredoxin_AhpC-typ IPR019479, Peroxiredoxin_C IPR036249, Thioredoxin-like_sf IPR013766, Thioredoxin_domain |
Pfami | View protein in Pfam PF10417, 1-cysPrx_C, 1 hit PF00578, AhpC-TSA, 1 hit |
PIRSFi | PIRSF000239, AHPC, 1 hit |
SUPFAMi | SSF52833, SSF52833, 1 hit |
PROSITEi | View protein in PROSITE PS51352, THIOREDOXIN_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q6FMP9_CANGA | |
Accessioni | Q6FMP9Primary (citable) accession number: Q6FMP9 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 19, 2004 |
Last sequence update: | July 19, 2004 | |
Last modified: | February 10, 2021 | |
This is version 102 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |