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UniProtKB - Q6FHZ7 (Q6FHZ7_HUMAN)
Protein
Perilipin
Gene
ADFP
Organism
Homo sapiens (Human)
Status
Functioni
GO - Biological processi
- lipid storage Source: Ensembl
- long-chain fatty acid transport Source: Ensembl
- response to organic cyclic compound Source: Ensembl
- response to xenobiotic stimulus Source: Ensembl
Names & Taxonomyi
Protein namesi | Recommended name: PerilipinUniRule annotation |
Gene namesi | Name:ADFPImported ORF Names:hCG_28271Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Organism-specific databases
VEuPathDBi | HostDB:ENSG00000147872 |
Subcellular locationi
Cytosol
- cytosol Source: Ensembl
Nucleus
- nucleus Source: Ensembl
Plasma Membrane
- plasma membrane Source: Ensembl
Other locations
- lipid droplet Source: HPA
Expressioni
Gene expression databases
Bgeei | ENSG00000147872, Expressed in pericardium and 232 other tissues |
Structurei
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 412 – 437 | DisorderedSequence analysisAdd BLAST | 26 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 260 – 280 | Sequence analysisAdd BLAST | 21 |
Sequence similaritiesi
Keywords - Domaini
Coiled coilSequence analysisPhylogenomic databases
HOGENOMi | CLU_035133_0_1_1 |
OMAi | QGKMLNN |
OrthoDBi | 1437332at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR004279, Perilipin |
Pfami | View protein in Pfam PF03036, Perilipin, 1 hit |
PIRSFi | PIRSF036881, PAT, 1 hit |
i Sequence
Sequence statusi: Complete.
Q6FHZ7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MASVAVDPQP SVVTRVVNLP LVSSTYDLMS SAYLSTKDQY PYLKSVCEMA
60 70 80 90 100
ENGVKTITSV AMTSALPIIQ KLEPQIAVAN TYACKGLDRI EERLPILNQP
110 120 130 140 150
STQIVANAKG AVTGAKDAVT TTVTGAKDSV ASTITGVMDK TKGAVTGSVE
160 170 180 190 200
KTKSVVSGSI NTVLGSRMMQ LVSSGVENAL TKSELLVEQY LPLTEEELEK
210 220 230 240 250
EAKKVEGFDL VQKPSYYVRL GSLSTKLHSR AYQQALSRVK EAKQKSQQTI
260 270 280 290 300
SQLHSTVHLI EFARKNVYSA NQKIQDAQDK LYLSWVEWKR SIGYDDTDES
310 320 330 340 350
HCAEHIESRT LAIARNLTQQ LQTTCHTLLS NIQGVPQNIQ DQAKHMGVMA
360 370 380 390 400
GDIYSVFRNA ASFKEVSDSL LTSSKGQLQK MKESLDDVMD YLVNNTPLNW
410 420 430
LVGPFYPQLT ESQNAQDQGA EMDKSSQETQ RSEHKTH
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK312983 mRNA Translation: BAG35820.1 CR536541 mRNA Translation: CAG38778.1 CH471071 Genomic DNA Translation: EAW58649.1 CH471071 Genomic DNA Translation: EAW58650.1 CH471071 Genomic DNA Translation: EAW58651.1 |
RefSeqi | NP_001113.2, NM_001122.3 |
Genome annotation databases
GeneIDi | 123 |
KEGGi | hsa:123 |
MANE-Selecti | ENST00000276914.7; ENSP00000276914.2; NM_001122.4; NP_001113.2 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK312983 mRNA Translation: BAG35820.1 CR536541 mRNA Translation: CAG38778.1 CH471071 Genomic DNA Translation: EAW58649.1 CH471071 Genomic DNA Translation: EAW58650.1 CH471071 Genomic DNA Translation: EAW58651.1 |
RefSeqi | NP_001113.2, NM_001122.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protocols and materials databases
Antibodypediai | 24726, 928 antibodies from 38 providers |
DNASUi | 123 |
Genome annotation databases
GeneIDi | 123 |
KEGGi | hsa:123 |
MANE-Selecti | ENST00000276914.7; ENSP00000276914.2; NM_001122.4; NP_001113.2 |
Organism-specific databases
CTDi | 123 |
PharmGKBi | PA24569 |
VEuPathDBi | HostDB:ENSG00000147872 |
Phylogenomic databases
HOGENOMi | CLU_035133_0_1_1 |
OMAi | QGKMLNN |
OrthoDBi | 1437332at2759 |
Miscellaneous databases
BioGRID-ORCSi | 123, 14 hits in 1082 CRISPR screens |
ChiTaRSi | PLIN2, human |
GenomeRNAii | 123 |
Gene expression databases
Bgeei | ENSG00000147872, Expressed in pericardium and 232 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR004279, Perilipin |
Pfami | View protein in Pfam PF03036, Perilipin, 1 hit |
PIRSFi | PIRSF036881, PAT, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Q6FHZ7_HUMAN | |
Accessioni | Q6FHZ7Primary (citable) accession number: Q6FHZ7 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 10, 2005 |
Last sequence update: | May 10, 2005 | |
Last modified: | May 25, 2022 | |
This is version 141 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |