SFRP4

Functionⁱ

Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types (By similarity). SFRP4 plays a role in bone morphogenesis. May also act as a regulator of adult uterine morphology and function. May also increase apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling (By similarity). Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake (PubMed:12952927).By similarity1 Publication

GO - Molecular functionⁱ

Wnt-protein binding
Source: MGI
Inferred from direct assayⁱ
- 17462603

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

bone morphogenesis
Source: UniProtKB
Inferred from mutant phenotypeⁱ
- 27355534
canonical Wnt signaling pathway
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
cell differentiation Source: UniProtKB-KW
negative regulation of canonical Wnt signaling pathway
Source: BHF-UCL
Inferred from direct assayⁱ
- 18945944
negative regulation of cell proliferation
Source: BHF-UCL
Inferred from mutant phenotypeⁱ
- 14760084
- 15705870
negative regulation of DNA-binding transcription factor activity
Source: BHF-UCL
Inferred from direct assayⁱ
- 18945944
negative regulation of non-canonical Wnt signaling pathway Source: UniProtKB
negative regulation of sodium-dependent phosphate transport
Source: BHF-UCL
Inferred from direct assayⁱ
- 12952927
- 16151791
negative regulation of Wnt signaling pathway
Source: ParkinsonsUK-UCL
Non-traceable author statementⁱ
- 24431302
non-canonical Wnt signaling pathway
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
phosphate ion homeostasis
Source: BHF-UCL
Inferred from direct assayⁱ
- 12952927
- 16151791
positive regulation of apoptotic process
Source: BHF-UCL
Inferred from mutant phenotypeⁱ
- 15705870
positive regulation of canonical Wnt signaling pathway
Source: MGI
Inferred from genetic interactionⁱ
- 18166153
positive regulation of epidermal cell differentiation
Source: BHF-UCL
Inferred from direct assayⁱ
- 18938133
positive regulation of gene expression
Source: BHF-UCL
Inferred from direct assayⁱ
- 18938133
positive regulation of keratinocyte apoptotic process
Source: BHF-UCL
Inferred from direct assayⁱ
- 18938133
positive regulation of receptor internalization
Source: BHF-UCL
Inferred from direct assayⁱ
- 16151791
regulation of BMP signaling pathway Source: UniProtKB
response to hormone
Source: BHF-UCL
Non-traceable author statementⁱ
- 10211996

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Developmental protein
Biological process	Differentiation, Wnt signaling pathway

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Secreted frizzled-related protein 4 Short name: sFRP-4 Alternative name(s): Frizzled protein, human endometrium Short name: FrpHE
Gene namesⁱ	Name:SFRP4 Synonyms:FRPHE
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 7

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000106483.11
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:10778 SFRP4
MIMⁱ	606570 gene
neXtProtⁱ	NX_Q6FHJ7

Keywords - Cellular componentⁱ

Secreted

Pathology & Biotechⁱ

Involvement in diseaseⁱ

Organism-specific databases

DisGeNET More...DisGeNETⁱ	6424
MalaCards human disease database More...MalaCardsⁱ	SFRP4
MIMⁱ	265900 phenotype
Open Targets More...OpenTargetsⁱ	ENSG00000106483
Orphanetⁱ	3005 Pyle disease
PharmGKBⁱ	PA35694

Polymorphism and mutation databases

BioMutaⁱ	SFRP4
DMDMⁱ	61216780

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Signal peptideⁱ	1 – 18	Sequence analysisAdd BLAST		18
ChainⁱPRO_0000032550	19 – 346	Secreted frizzled-related protein 4Add BLAST		328

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Disulfide bondⁱ	24 ↔ 85	By similarity
Disulfide bondⁱ	32 ↔ 78	By similarity
Glycosylationⁱ	38	N-linked (GlcNAc...) asparagineSequence analysis	1
Glycosylationⁱ	68	N-linked (GlcNAc...) asparagineSequence analysis	1
Disulfide bondⁱ	69 ↔ 108	By similarity
Disulfide bondⁱ	97 ↔ 136	By similarity
Disulfide bondⁱ	101 ↔ 125	By similarity
Glycosylationⁱ	116	N-linked (GlcNAc...) asparagineSequence analysis	1
Glycosylationⁱ	194	N-linked (GlcNAc...) asparagineSequence analysis	1
Glycosylationⁱ	240	N-linked (GlcNAc...) asparagineSequence analysis	1

Keywords - PTMⁱ

Disulfide bond, Glycoprotein

Proteomic databases

EPDⁱ	Q6FHJ7
PaxDbⁱ	Q6FHJ7
PeptideAtlas More...PeptideAtlasⁱ	Q6FHJ7
PRIDEⁱ	Q6FHJ7
ProteomicsDBⁱ	66293

PTM databases

GlyConnectⁱ	1726
iPTMnetⁱ	Q6FHJ7
PhosphoSitePlusⁱ	Q6FHJ7

Expressionⁱ

Tissue specificityⁱ

Expressed in mesenchymal cells. Highly expressed in the stroma of proliferative endometrium. Expressed in cardiomyocytes. Shows moderate to strong expression in ovarian tumors with expression increasing as the tumor stage increases. In ovarian tumors, expression levels are inversely correlated with expression of CTNNB1 (at protein level).2 Publications

Inductionⁱ

Increased levels in failing myocardium. Up-regulated in several tumor types including ostomalacia-associated tumors and endometrial and breast carcinomas.

Gene expression databases

Bgeeⁱ	ENSG00000106483 Expressed in 178 organ(s), highest expression level in connective tissue
CleanExⁱ	HS_SFRP4
ExpressionAtlasⁱ	Q6FHJ7 baseline and differential
Genevisibleⁱ	Q6FHJ7 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA009712 HPA050585

HPAⁱ

HPA009712
HPA050585

Interactionⁱ

GO - Molecular functionⁱ

Wnt-protein binding
Source: MGI
Inferred from direct assayⁱ
- 17462603

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

BioGridⁱ	112322, 19 interactors
IntActⁱ	Q6FHJ7, 22 interactors
Molecular INTeraction database More...MINTⁱ	Q6FHJ7
STRINGⁱ	9606.ENSP00000410715

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q6FHJ7
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	19 – 139	FZPROSITE-ProRule annotationAdd BLAST		121
Domainⁱ	178 – 307	NTRPROSITE-ProRule annotationAdd BLAST		130

Domainⁱ

The FZ domain is involved in binding with Wnt ligands.By similarity

Sequence similaritiesⁱ

Belongs to the secreted frizzled-related protein (sFRP) family.Curated

Keywords - Domainⁱ

Signal

Phylogenomic databases

eggNOGⁱ	KOG3577 Eukaryota ENOG410XRC8 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000118864
HOVERGENⁱ	HBG070536
InParanoidⁱ	Q6FHJ7
KEGG Orthology (KO) More...KOⁱ	K02185
OMAⁱ	YAPICAL
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0BGB
PhylomeDBⁱ	Q6FHJ7

Family and domain databases

Gene3Dⁱ	1.10.2000.10, 1 hit
InterProⁱ	View protein in InterPro IPR015526 Frizzled/SFRP IPR020067 Frizzled_dom IPR036790 Frizzled_dom_sf IPR001134 Netrin_domain IPR018933 Netrin_module_non-TIMP IPR026560 SFRP4 IPR008993 TIMP-like_OB-fold
PANTHERⁱ	PTHR11309 PTHR11309, 1 hit PTHR11309:SF7 PTHR11309:SF7, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF01392 Fz, 1 hit PF01759 NTR, 1 hit
SMARTⁱ	View protein in SMART SM00643 C345C, 1 hit SM00063 FRI, 1 hit
SUPFAMⁱ	SSF50242 SSF50242, 1 hit SSF63501 SSF63501, 1 hit
PROSITEⁱ	View protein in PROSITE PS50038 FZ, 1 hit PS50189 NTR, 1 hit

Sequence (1+)ⁱ

Sequence statusⁱ: Complete.

Sequence processingⁱ: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show all Align All

Q6FHJ7-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MFLSILVALC LWLHLALGVR GAPCEAVRIP MCRHMPWNIT RMPNHLHHST 
        60         70         80         90        100
QENAILAIEQ YEELVDVNCS AVLRFFLCAM YAPICTLEFL HDPIKPCKSV 
       110        120        130        140        150
CQRARDDCEP LMKMYNHSWP ESLACDELPV YDRGVCISPE AIVTDLPEDV 
       160        170        180        190        200
KWIDITPDMM VQERPLDVDC KRLSPDRCKC KKVKPTLATY LSKNYSYVIH 
       210        220        230        240        250
AKIKAVQRSG CNEVTTVVDV KEIFKSSSPI PRTQVPLITN SSCQCPHILP 
       260        270        280        290        300
HQDVLIMCYE WRSRMMLLEN CLVEKWRDQL SKRSIQWEER LQEQRRTVQD 
       310        320        330        340 
KKKTAGRTSR SNPPKPKGKP PAPKPASPKK NIKTRSAQKR TNPKRV

Length:346

Mass (Da):39,827

Last modified:March 15, 2005 - v2

Checksum:ⁱ75D04089E446CE80

GO

Computationally mapped potential isoform sequencesⁱ

There is 1 potential isoform mapped to this entry.BLAST Align Show all Add to basket

	Entry	Entry name		Protein names	Gene names	Length	Annotation

	C9JMJ2	C9JMJ2_HUMAN		Secreted frizzled-related protein 4 Secreted frizzled-related protein 4	SFRP4	137	Annotation score:

Sequence cautionⁱ

The sequence BAG63683 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature key	Position(s)	DescriptionActions	Length
Sequence conflictⁱ	19	V → M in CAG46532 (Ref. 5) Curated	1
Sequence conflictⁱ	77	L → F in AAC04617 (PubMed:10211996).Curated	1
Sequence conflictⁱ	141	A → V in CAG46555 (Ref. 5) Curated	1

Natural variant

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Natural variantⁱVAR_051964	320	P → T4 PublicationsCorresponds to variant dbSNP:rs1802073Ensembl.		1
Natural variantⁱVAR_051965	340	R → K2 PublicationsCorresponds to variant dbSNP:rs1802074Ensembl.		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF026692 mRNA Translation: AAC04617.1 DQ420628 mRNA Translation: ABD83351.1 AK302357 mRNA Translation: BAG63683.1 Different initiation. CR541731 mRNA Translation: CAG46532.1 CR541755 mRNA Translation: CAG46555.1 BT019679 mRNA Translation: AAV38485.1 CH236951 Genomic DNA Translation: EAL23981.1 BC047684 mRNA Translation: AAH47684.1 BC058911 mRNA Translation: AAH58911.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS5453.1
NCBI Reference Sequences More...RefSeqⁱ	NP_003005.2, NM_003014.3
UniGeneⁱ	Hs.658169

Genome annotation databases

Ensemblⁱ	ENST00000436072; ENSP00000410715; ENSG00000106483
GeneIDⁱ	6424
KEGGⁱ	hsa:6424
UCSC genome browser More...UCSCⁱ	uc003tfo.5 human

Keywords - Coding sequence diversityⁱ

Polymorphism

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q6FHJ7	Uncharacterized protein		PANPA		368	UniRef100_Q6FHJ7

Protein	Similar proteins		Species	Score	Length	Source
Q6FHJ7	Uncharacterized protein		PANPA		368	UniRef90_Q6FHJ7
Secreted frizzled related protein 4		CALJA		369
Uncharacterized protein		NOMLE		369
Uncharacterized protein		AOTNA		369
Secreted frizzled related protein 4		SAIBB		369
+32

Protein	Similar proteins		Species	Score	Length	Source
Q6FHJ7	Secreted frizzled-related protein 4		MACMU		346	UniRef50_Q6FHJ7
Secreted frizzled-related sequence protein 4		MOUSE		351
Secreted frizzled-related protein 4		RAT		348
Uncharacterized protein		PANPA		368
Secreted frizzled related protein 4		SAIBB		369
+175

Cross-referencesⁱ

Web resourcesⁱ

Atlas of Genetics and Cytogenetics in Oncology and Haematology

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF026692 mRNA Translation: AAC04617.1 DQ420628 mRNA Translation: ABD83351.1 AK302357 mRNA Translation: BAG63683.1 Different initiation. CR541731 mRNA Translation: CAG46532.1 CR541755 mRNA Translation: CAG46555.1 BT019679 mRNA Translation: AAV38485.1 CH236951 Genomic DNA Translation: EAL23981.1 BC047684 mRNA Translation: AAH47684.1 BC058911 mRNA Translation: AAH58911.1
CCDSⁱ	CCDS5453.1
RefSeqⁱ	NP_003005.2, NM_003014.3
UniGeneⁱ	Hs.658169

3D structure databases

ProteinModelPortalⁱ	Q6FHJ7
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	112322, 19 interactors
IntActⁱ	Q6FHJ7, 22 interactors
MINTⁱ	Q6FHJ7
STRINGⁱ	9606.ENSP00000410715

PTM databases

GlyConnectⁱ	1726
iPTMnetⁱ	Q6FHJ7
PhosphoSitePlusⁱ	Q6FHJ7

Polymorphism and mutation databases

BioMutaⁱ	SFRP4
DMDMⁱ	61216780

Proteomic databases

EPDⁱ	Q6FHJ7
PaxDbⁱ	Q6FHJ7
PeptideAtlasⁱ	Q6FHJ7
PRIDEⁱ	Q6FHJ7
ProteomicsDBⁱ	66293

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	6424
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000436072; ENSP00000410715; ENSG00000106483
GeneIDⁱ	6424
KEGGⁱ	hsa:6424
UCSCⁱ	uc003tfo.5 human

Organism-specific databases

CTDⁱ	6424
DisGeNETⁱ	6424
EuPathDBⁱ	HostDB:ENSG00000106483.11
GeneCardsⁱ	SFRP4
H-InvDBⁱ	HIX0033524
HGNCⁱ	HGNC:10778 SFRP4
HPAⁱ	HPA009712 HPA050585
MalaCardsⁱ	SFRP4
MIMⁱ	265900 phenotype 606570 gene
neXtProtⁱ	NX_Q6FHJ7
OpenTargetsⁱ	ENSG00000106483
Orphanetⁱ	3005 Pyle disease
PharmGKBⁱ	PA35694
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG3577 Eukaryota ENOG410XRC8 LUCA
GeneTreeⁱ	ENSGT00760000118864
HOVERGENⁱ	HBG070536
InParanoidⁱ	Q6FHJ7
KOⁱ	K02185
OMAⁱ	YAPICAL
OrthoDBⁱ	EOG091G0BGB
PhylomeDBⁱ	Q6FHJ7

Miscellaneous databases

ChiTaRSⁱ	SFRP4 human
GeneWikiⁱ	SFRP4
GenomeRNAiⁱ	6424
Protein Ontology More...PROⁱ	PR:Q6FHJ7
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000106483 Expressed in 178 organ(s), highest expression level in connective tissue
CleanExⁱ	HS_SFRP4
ExpressionAtlasⁱ	Q6FHJ7 baseline and differential
Genevisibleⁱ	Q6FHJ7 HS

Family and domain databases

Gene3Dⁱ	1.10.2000.10, 1 hit
InterProⁱ	View protein in InterPro IPR015526 Frizzled/SFRP IPR020067 Frizzled_dom IPR036790 Frizzled_dom_sf IPR001134 Netrin_domain IPR018933 Netrin_module_non-TIMP IPR026560 SFRP4 IPR008993 TIMP-like_OB-fold
PANTHERⁱ	PTHR11309 PTHR11309, 1 hit PTHR11309:SF7 PTHR11309:SF7, 1 hit
Pfamⁱ	View protein in Pfam PF01392 Fz, 1 hit PF01759 NTR, 1 hit
SMARTⁱ	View protein in SMART SM00643 C345C, 1 hit SM00063 FRI, 1 hit
SUPFAMⁱ	SSF50242 SSF50242, 1 hit SSF63501 SSF63501, 1 hit
PROSITEⁱ	View protein in PROSITE PS50038 FZ, 1 hit PS50189 NTR, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	SFRP4_HUMAN
Accessionⁱ	Q6FHJ7Primary (citable) accession number: Q6FHJ7 Secondary accession number(s): B4DYC1 Q6PD64
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	March 15, 2005
	Last sequence update:	March 15, 2005
	Last modified:	November 7, 2018
	This is version 144 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
Human chromosome 7
Human chromosome 7: entries, gene names and cross-references to MIM

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UniRef

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Supporting data

UniProtKB - Q6FHJ7 (SFRP4_HUMAN)

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Secreted frizzled-related protein 4

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted

Extracellular region or secreted

Nucleus

Other locations

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

Experimental Info

Natural variant

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross_references_section">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Sequence cautionⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Web resourcesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ