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Protein
Submitted name:

KCNE1 protein

Gene

KCNE1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • cellular response to cAMP Source: BHF-UCL
  • potassium ion transmembrane transport Source: BHF-UCL

Protein family/group databases

TCDBi8.A.10.1.2 the slow voltage-gated k+) channel accessory protein (mink) family

Names & Taxonomyi

Protein namesi
Submitted name:
KCNE1 proteinImported
Submitted name:
Potassium voltage-gated channel Isk-related family member 1Imported
Submitted name:
Potassium voltage-gated channel, Isk-related family, member 1Imported
Submitted name:
cDNA, FLJ94103, Homo sapiens potassium voltage-gated channel, Isk-related family,member 1 (KCNE1), mRNAImported
Gene namesi
Name:KCNE1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei44 – 66HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA211

Interactioni

Binary interactionsi

Protein-protein interaction databases

IntActiQ6FHJ6, 2 interactors

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IY71 Eukaryota
ENOG410Y1SF LUCA
HOVERGENiHBG052226
KOiK04894

Family and domain databases

InterProiView protein in InterPro
IPR000369 K_chnl_KCNE
IPR005424 K_chnl_volt-dep_bsu_KCNE1
PANTHERiPTHR15282 PTHR15282, 1 hit
PfamiView protein in Pfam
PF02060 ISK_Channel, 1 hit
PRINTSiPR01604 KCNE1CHANNEL
PR00168 KCNECHANNEL

Sequencei

Sequence statusi: Fragment.

Q6FHJ6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MILSNTTAVT PFLTKLWQET VQQGGNMSGL ARRSPRSGDG KLEALYVLMV
60 70 80 90 100
LGFFGFFTLG IMLSYIRSKK LEHSNDPFNV YIESDAWQEK DKAYVQARVL
110 120
ESYRSCYVVE NHLAIEQPNT HLPETKPSP
Length:129
Mass (Da):14,645
Last modified:May 10, 2005 - v1
Checksum:i4843171C7DC1A92A
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei129Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC046224 mRNA Translation: AAH46224.1
EF514883 mRNA Translation: ABS84251.1
EF514884 Genomic DNA Translation: ABS84252.1
AK313543 mRNA Translation: BAG36319.1
CR541756 mRNA Translation: CAG46556.1
RefSeqiNP_000210.2, NM_000219.5
UniGeneiHs.121495
Hs.745384

Genome annotation databases

GeneIDi3753
KEGGihsa:3753

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC046224 mRNA Translation: AAH46224.1
EF514883 mRNA Translation: ABS84251.1
EF514884 Genomic DNA Translation: ABS84252.1
AK313543 mRNA Translation: BAG36319.1
CR541756 mRNA Translation: CAG46556.1
RefSeqiNP_000210.2, NM_000219.5
UniGeneiHs.121495
Hs.745384

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ6FHJ6, 2 interactors

Protein family/group databases

TCDBi8.A.10.1.2 the slow voltage-gated k+) channel accessory protein (mink) family

Protocols and materials databases

DNASUi3753
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi3753
KEGGihsa:3753

Organism-specific databases

CTDi3753
PharmGKBiPA211

Phylogenomic databases

eggNOGiENOG410IY71 Eukaryota
ENOG410Y1SF LUCA
HOVERGENiHBG052226
KOiK04894

Miscellaneous databases

ChiTaRSiKCNE1 human
GenomeRNAii3753

Family and domain databases

InterProiView protein in InterPro
IPR000369 K_chnl_KCNE
IPR005424 K_chnl_volt-dep_bsu_KCNE1
PANTHERiPTHR15282 PTHR15282, 1 hit
PfamiView protein in Pfam
PF02060 ISK_Channel, 1 hit
PRINTSiPR01604 KCNE1CHANNEL
PR00168 KCNECHANNEL
ProtoNetiSearch...

Entry informationi

Entry nameiQ6FHJ6_HUMAN
AccessioniPrimary (citable) accession number: Q6FHJ6
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: October 10, 2018
This is version 98 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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