RAB7L1

Functionⁱ

GO - Molecular functionⁱ

GDP binding Source: Ensembl
GTPase activity Source: InterPro
GTP binding Source: Ensembl

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

regulation of retrograde transport, endosome to Golgi Source: Ensembl
vesicle-mediated transport Source: InterPro

View the complete GO annotation on QuickGO ...

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: RAB7, member RAS oncogene family-like 1Imported Submitted name: RAB7, member RAS oncogene family-like 1, isoform CRA_aImported Submitted name: RAB7L1 proteinImported
Gene namesⁱ	Name:RAB7L1Imported ORF Names:hCG_19156Imported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000117280.12

EuPathDBⁱ

HostDB:ENSG00000117280.12

Subcellular locationⁱ

GO - Cellular component

Pathology & Biotechⁱ

Organism-specific databases

PharmGKBⁱ	PA34151

PharmGKBⁱ

PA34151

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000117280 Expressed in 223 organ(s), highest expression level in nephron tubule

Bgeeⁱ

ENSG00000117280 Expressed in 223 organ(s), highest expression level in nephron tubule

Interactionⁱ

Binary interactionsⁱ

With	Entry	#Exp.	IntAct
BEND7	Q8N7W2-2	3	EBI-10249635,EBI-10181188
C11orf49	Q9H6J7	3	EBI-10249635,EBI-721300
LDOC1	O95751	3	EBI-10249635,EBI-740738
TRIM27	P14373	3	EBI-10249635,EBI-719493

Protein-protein interaction databases

IntActⁱ	Q6FGU7, 4 interactors Q6FGU7, 4 interactors

IntActⁱ

Q6FGU7, 4 interactors
Q6FGU7, 4 interactors

Family & Domainsⁱ

Phylogenomic databases

eggNOGⁱ	KOG4423 Eukaryota ENOG410YITC LUCA
HOVERGENⁱ	HBG009351
KEGG Orthology (KO) More...KOⁱ	K07916
OMAⁱ	QERFISM
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0K53

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd04107 Rab32_Rab38, 1 hit
InterProⁱ	View protein in InterPro IPR027417 P-loop_NTPase IPR030697 Rab29/Rab38/Rab32 IPR005225 Small_GTP-bd_dom IPR001806 Small_GTPase
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00071 Ras, 1 hit
SUPFAMⁱ	SSF52540 SSF52540, 1 hit
TIGRFAMsⁱ	TIGR00231 small_GTP, 1 hit

Sequenceⁱ

Sequence statusⁱ: Fragment.

Q6FGU7-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MGSRDHLFKV LVVGDAAVGK TSLVQRYSQD SFSKHYKSTV GVDFALKVLQ 
        60         70         80         90        100
WSDYEIVRLQ LWDIAGQERF TSMTRLYYRD ASACVIMFDV TNATTFSNSQ 
       110        120        130        140        150
RWKQDLDSKL TLPNGEPVPC LLLANKCDLS PWAVSRDQID RFSKENGFTG 
       160        170        180        190        200
WTETSVKENK NINEAMRVLI EKMMRNSTED IMSLSTQGDY INLQTKSSSW 

SCC

Length:203

Mass (Da):23,155

Last modified:May 10, 2005 - v1

Checksum:ⁱ40E7CAB02446DF97

GO

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Non-terminal residueⁱ	203	Imported		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BT019540 mRNA Translation: AAV38347.1 CR542010 mRNA Translation: CAG46807.1 CH471067 Genomic DNA Translation: EAW91580.1 CH471067 Genomic DNA Translation: EAW91581.1
NCBI Reference Sequences More...RefSeqⁱ	NP_001129134.1, NM_001135662.1 NP_003920.1, NM_003929.2 XP_005245626.1, XM_005245569.1 XP_005245627.1, XM_005245570.1 XP_005245628.1, XM_005245571.1
UniGeneⁱ	Hs.115325

Genome annotation databases

GeneIDⁱ	8934
KEGGⁱ	hsa:8934
UCSC genome browser More...UCSCⁱ	uc001hde.5 human

Protein	Similar proteins		Species	Score	Length	Source
Q6FGU7	Ras-related protein Rab-7L1		HUMAN		203	UniRef100_O14966
Ras-related protein Rab-7L1		PONAB		203
RAB29 isoform 2		PANTR		203
Uncharacterized protein		PANPA		203
Uncharacterized protein		NOMLE		203
+4

Protein	Similar proteins		Species	Score	Length	Source
Q6FGU7	Ras-related protein Rab-7L1		HUMAN		203	UniRef90_O14966
Ras-related protein Rab-7L1		PONAB		203
Ras-related protein Rab-7L1		RAT		204
Ras-related protein Rab-7L1		MOUSE		204
RAB29 isoform 2		PANTR		203
+132

Protein	Similar proteins		Species	Score	Length	Source
Q6FGU7	Ras-related protein Rab-7L1		HUMAN		203	UniRef50_O14966
Ras-related protein Rab-7L1		PONAB		203
Ras-related protein Rab-7L1		MOUSE		204
Ras-related protein Rab-7L1		RAT		204
RAB29 isoform 2		PANTR		203
+156

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BT019540 mRNA Translation: AAV38347.1 CR542010 mRNA Translation: CAG46807.1 CH471067 Genomic DNA Translation: EAW91580.1 CH471067 Genomic DNA Translation: EAW91581.1
RefSeqⁱ	NP_001129134.1, NM_001135662.1 NP_003920.1, NM_003929.2 XP_005245626.1, XM_005245569.1 XP_005245627.1, XM_005245570.1 XP_005245628.1, XM_005245571.1
UniGeneⁱ	Hs.115325

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

IntActⁱ	Q6FGU7, 4 interactors Q6FGU7, 4 interactors

IntActⁱ

Q6FGU7, 4 interactors
Q6FGU7, 4 interactors

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	8934
Structural Biology Knowledgebase	Search...

Genome annotation databases

GeneIDⁱ	8934
KEGGⁱ	hsa:8934
UCSCⁱ	uc001hde.5 human

Organism-specific databases

CTDⁱ	8934
EuPathDBⁱ	HostDB:ENSG00000117280.12
PharmGKBⁱ	PA34151

Phylogenomic databases

eggNOGⁱ	KOG4423 Eukaryota ENOG410YITC LUCA
HOVERGENⁱ	HBG009351
KOⁱ	K07916
OMAⁱ	QERFISM
OrthoDBⁱ	EOG091G0K53

Miscellaneous databases

ChiTaRSⁱ	RAB29 human
GenomeRNAiⁱ	8934

Gene expression databases

Bgeeⁱ	ENSG00000117280 Expressed in 223 organ(s), highest expression level in nephron tubule

Bgeeⁱ

ENSG00000117280 Expressed in 223 organ(s), highest expression level in nephron tubule

Family and domain databases

CDDⁱ	cd04107 Rab32_Rab38, 1 hit
InterProⁱ	View protein in InterPro IPR027417 P-loop_NTPase IPR030697 Rab29/Rab38/Rab32 IPR005225 Small_GTP-bd_dom IPR001806 Small_GTPase
Pfamⁱ	View protein in Pfam PF00071 Ras, 1 hit
SUPFAMⁱ	SSF52540 SSF52540, 1 hit
TIGRFAMsⁱ	TIGR00231 small_GTP, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q6FGU7_HUMAN
Accessionⁱ	Q6FGU7Primary (citable) accession number: Q6FGU7
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	May 10, 2005
	Last sequence update:	May 10, 2005
	Last modified:	November 7, 2018
	This is version 131 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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UniProtKB - Q6FGU7 (Q6FGU7_HUMAN)

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RAB7, member RAS oncogene family-like 1

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Golgi apparatus

Other locations

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

Family and domain databases

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Pathology & Biotechⁱ

Expressionⁱ

Interactionⁱ

Family & Domainsⁱ

Cross-referencesⁱ

Entry informationⁱ