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Entry version 100 (12 Aug 2020)
Sequence version 2 (05 Apr 2011)
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Protein

Protein ACCUMULATION AND REPLICATION OF CHLOROPLASTS 3

Gene

ARC3

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Z-ring accessory protein involved in the initiation of plastid division and division site placement (might functionally replace bacterial MinC). May control the rate of chloroplast expansion. Seems to influence stromule (stroma-filled tubular extensions of the plastid envelope membrane) length and frequency.4 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

  • chloroplast fission Source: UniProtKB

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein ACCUMULATION AND REPLICATION OF CHLOROPLASTS 3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ARC3
Ordered Locus Names:At1g75010
ORF Names:F25A4.3, F9E10.14
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT1G75010

The Arabidopsis Information Resource

More...
TAIRi
locus:2027242, AT1G75010

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Chloroplast, Membrane, Plastid, Plastid outer membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Small number of abnormally large and heterogeneous chloroplasts sometimes exhibiting alteration in stromule length and frequency in non-green tissues (e.g. slightly increased stromule frequency in hypocotyl epidermal cells).4 Publications

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a transit peptide.<p><a href='/help/transit' target='_top'>More...</a></p>Transit peptidei1 – 41ChloroplastSequence analysisAdd BLAST41
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000040623042 – 741Protein ACCUMULATION AND REPLICATION OF CHLOROPLASTS 3Add BLAST700

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q6F6B5

PRoteomics IDEntifications database

More...
PRIDEi
Q6F6B5

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
244457

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q6F6B5, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q6F6B5, AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Self-interacts.

Interacts with FTSZ, CDP1 (via N-terminus), MIND1 and MINE1.

Part of a complex made of ARC3, ARC6, FTSZ1 and FTSZ2.

4 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
29058, 3 interactors

Protein interaction database and analysis system

More...
IntActi
Q6F6B5, 5 interactors

Molecular INTeraction database

More...
MINTi
Q6F6B5

STRING: functional protein association networks

More...
STRINGi
3702.AT1G75010.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q6F6B5

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati612 – 628MORN 1Add BLAST17
Repeati630 – 652MORN 2Add BLAST23
Repeati653 – 675MORN 3Add BLAST23

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili214 – 237Sequence analysisAdd BLAST24
Coiled coili421 – 441Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coil, Repeat, Transit peptide

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0231, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_382379_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q6F6B5

Identification of Orthologs from Complete Genome Data

More...
OMAi
IYRGRCQ

Database of Orthologous Groups

More...
OrthoDBi
376216at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q6F6B5

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.50.1440, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003409, MORN
IPR036525, Tubulin/FtsZ_GTPase_sf
IPR003008, Tubulin_FtsZ_GTPase

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02493, MORN, 3 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00423, CELLDVISFTSZ

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00698, MORN, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52490, SSF52490, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q6F6B5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPISMELPVF STLRVPLFSR LALLPTFGVP FSSLGATTRL NCTSRKARRI
60 70 80 90 100
CVMCLVRDSA PIETCERAGE DGSDEFIEVL VIGSRKESIM DSCLDSPFPS
110 120 130 140 150
LPLRFWSISK DSSGGLVLQQ RLNHQDNALK TMNPIELLQS RPRAFILVAS
160 170 180 190 200
AGYGSDQVEA INILSAVRSG GNLAVAVLLK PFSFEGRKRL EEVNELARKL
210 220 230 240 250
QQHTNFCIDI DIEVLLQKDL VTLDEALRNA NNAVSMAINA ASALISGMHG
260 270 280 290 300
NFIDVMHKDL KELEGSEVKT ILESYKEAKV GFGVGHNLKT SILRAIYDCP
310 320 330 340 350
FFRPGLKDLN AIICIVASSV PLQKKDVKTI LRTFRQTMEY TGDIIVSTVH
360 370 380 390 400
EPDLEPKVRV TTFFILSSSE VETSNKGNIF SGLVPFVLNI FTRYRSQLQK
410 420 430 440 450
ETNIGLGETP VSIKDSADST DVKTSNQNIE EFEIDSEDLL EVSENGDDSE
460 470 480 490 500
YPLKEGEPSR NSRLDLKDEN VEDFGAIQRE PIANWSMDQG YQIEQKWQAD
510 520 530 540 550
SGDTAVLSLG IVNLPVGVRP SKKLNSNLSV ASQLSRKADS REESFFNPNG
560 570 580 590 600
STKDSSDTAS TLLSEKYADF TKQRNLSARA SSMLEAERDS SKRWSPILEM
610 620 630 640 650
QYRGGLFKGR CQGGLPEGKG RLVLGDGSIY DGMWHNGKRS GLGTFYFKNG
660 670 680 690 700
DVFQGTWRED LIHGKGWFYF HKGDRWFANF WKGKASGEGR FYSKSGEIFF
710 720 730 740
GHFKDGWRHG QFLCIDLDGT RYSETWDDGV LIDRKQVDAG D
Length:741
Mass (Da):82,583
Last modified:April 5, 2011 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3CA934BB03EB9DEF
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAD55276 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence AAG51935 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence BAE99720 differs from that shown. Intron retention.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti129L → S in BAD26731 (PubMed:15356321).Curated1
Sequence conflicti371V → E in BAD26731 (PubMed:15356321).Curated1
Sequence conflicti422V → I in BAD26731 (PubMed:15356321).Curated1
Sequence conflicti429I → V in BAD26731 (PubMed:15356321).Curated1
Sequence conflicti670F → L in BAD26731 (PubMed:15356321).Curated1
Sequence conflicti730V → A in BAE99720 (Ref. 4) Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB094044 mRNA Translation: BAD26731.1
AC008263 Genomic DNA Translation: AAD55276.1 Sequence problems.
AC013258 Genomic DNA Translation: AAG51935.1 Sequence problems.
CP002684 Genomic DNA Translation: AEE35661.1
AK227735 mRNA Translation: BAE99720.1 Sequence problems.

Protein sequence database of the Protein Information Resource

More...
PIRi
A96780

NCBI Reference Sequences

More...
RefSeqi
NP_177638.2, NM_106158.5

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT1G75010.1; AT1G75010.1; AT1G75010

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
843839

Gramene; a comparative resource for plants

More...
Gramenei
AT1G75010.1; AT1G75010.1; AT1G75010

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT1G75010

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB094044 mRNA Translation: BAD26731.1
AC008263 Genomic DNA Translation: AAD55276.1 Sequence problems.
AC013258 Genomic DNA Translation: AAG51935.1 Sequence problems.
CP002684 Genomic DNA Translation: AEE35661.1
AK227735 mRNA Translation: BAE99720.1 Sequence problems.
PIRiA96780
RefSeqiNP_177638.2, NM_106158.5

3D structure databases

SMRiQ6F6B5
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi29058, 3 interactors
IntActiQ6F6B5, 5 interactors
MINTiQ6F6B5
STRINGi3702.AT1G75010.1

Proteomic databases

PaxDbiQ6F6B5
PRIDEiQ6F6B5
ProteomicsDBi244457

Genome annotation databases

EnsemblPlantsiAT1G75010.1; AT1G75010.1; AT1G75010
GeneIDi843839
GrameneiAT1G75010.1; AT1G75010.1; AT1G75010
KEGGiath:AT1G75010

Organism-specific databases

AraportiAT1G75010
TAIRilocus:2027242, AT1G75010

Phylogenomic databases

eggNOGiKOG0231, Eukaryota
HOGENOMiCLU_382379_0_0_1
InParanoidiQ6F6B5
OMAiIYRGRCQ
OrthoDBi376216at2759
PhylomeDBiQ6F6B5

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q6F6B5

Gene expression databases

ExpressionAtlasiQ6F6B5, baseline and differential
GenevisibleiQ6F6B5, AT

Family and domain databases

Gene3Di3.40.50.1440, 1 hit
InterProiView protein in InterPro
IPR003409, MORN
IPR036525, Tubulin/FtsZ_GTPase_sf
IPR003008, Tubulin_FtsZ_GTPase
PfamiView protein in Pfam
PF02493, MORN, 3 hits
PRINTSiPR00423, CELLDVISFTSZ
SMARTiView protein in SMART
SM00698, MORN, 2 hits
SUPFAMiSSF52490, SSF52490, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiARC3_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6F6B5
Secondary accession number(s): Q0WT28, Q9C9P7, Q9SSG9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 5, 2011
Last sequence update: April 5, 2011
Last modified: August 12, 2020
This is version 100 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
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