Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 40 (10 Feb 2021)
Sequence version 1 (16 Aug 2004)
Previous versions | rss
Add a publicationFeedback
Protein

Benzyl alcohol O-benzoyltransferase

Gene

BEBT1

Organism
Petunia hybrida (Petunia)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in the production of volatile organic compounds (VOCs), including floral volatile benzenoids and phenylpropanoids (FVBP), in flowers of fragrant cultivars (e.g. cv. Mitchell and cv. V26), scent attracting pollinators (e.g. the night-active hawkmoth pollinator Manduca sexta) (PubMed:15286288, PubMed:20070567).

Acyltransferase that catalyzes the transfer of benzoyl and acetyl moieties to a large variety of potential substrate alcohols, and involved in the formation of volatile esters benzyl benzoate and phenylethyl benzoate from benzoyl-CoA (PubMed:15286288, PubMed:17194766, PubMed:20070567).

With acetyl-CoA, mainly active on benzyl alcohol, and, to a lower extent, on 3-hydroxybenzyl alcohol, geraniol, and 2-phenylethanol, but barely active on butanol, 1-octanol, 4-hydroxy-benzyl alcohol, 2-hexanol, cis-3-hexen-1-ol and linalool (PubMed:15286288).

With benzoyl-CoA, mainly active on benzyl alcohol, but also efficient on several substrates, including 3-hydroxybenzyl alcohol, 2-phenylethanol, geraniol, butanol, cis-3-hexen-1-ol and 1-octanol (PubMed:15286288).

3 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Function' section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

kcat is 4.4 sec(-1) with acetyl-CoA as substrate (PubMed:15286288). kcat is 57.1 sec(-1) with benzoyl-CoA as substrate (in the presence of benzyl alcohol) (PubMed:15286288). kcat is 81.3 sec(-1) with benzoyl-CoA as substrate (in the presence of phenyl alcohol) (PubMed:15286288). kcat is 1.61 sec(-1) with benzyl alcohol as substrate (in the presence of acetyl-CoA) (PubMed:15286288). kcat is 36.9 sec(-1) with benzyl alcohol as substrate (in the presence of benzoyl-CoA) (PubMed:15286288). kcat is 35.8 sec(-1) with phenyl ethanol as substrate (in the presence of benzoyl-CoA) (PubMed:15286288).1 Publication
  1. KM=682 µM for acetyl-CoA1 Publication
  2. KM=1555 µM for benzoyl-CoA (in the presence of benzyl alcohol)1 Publication
  3. KM=875 µM for benzoyl-CoA (in the presence of phenyl alcohol)1 Publication
  4. KM=28.6 µM for benzyl alcohol (in the presence of acetyl-CoA)1 Publication
  5. KM=444 µM for benzyl alcohol (in the presence of benzoyl-CoA)1 Publication
  6. KM=686 µM for phenyl ethanol (in the presence of benzoyl-CoA)1 Publication
  1. Vmax=15 nmol/sec/mg enzyme with acetyl-CoA as substrate1 Publication
  2. Vmax=194 nmol/sec/mg enzyme with benzoyl-CoA as substrate (in the presence of benzyl alcohol)1 Publication
  3. Vmax=279 nmol/sec/mg enzyme with benzoyl-CoA as substrate (in the presence of phenyl alcohol)1 Publication
  4. Vmax=5.52 nmol/sec/mg enzyme with benzyl alcohol as substrate (in the presence of acetyl-CoA)1 Publication
  5. Vmax=125.5 nmol/sec/mg enzyme with benzyl alcohol as substrate (in the presence of benzoyl-CoA)1 Publication
  6. Vmax=122.9 nmol/sec/mg enzyme with phenyl ethanol as substrate (in the presence of benzoyl-CoA)1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: benzoyl-CoA degradation

This protein is involved in the pathway benzoyl-CoA degradation, which is part of Aromatic compound metabolism.1 Publication
View all proteins of this organism that are known to be involved in the pathway benzoyl-CoA degradation and in Aromatic compound metabolism.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei167Proton acceptorSequence analysis1
Active sitei382Proton acceptorSequence analysis1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionAcyltransferase, Transferase

Enzyme and pathway databases

BRENDA Comprehensive Enzyme Information System

More...
BRENDAi
2.3.1.196, 4700

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00739

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Benzyl alcohol O-benzoyltransferase1 Publication (EC:2.3.1.1961 Publication)
Short name:
PhBEBT11 Publication
Alternative name(s):
Acetyl CoA:3-hydroxybenzyl alcohol acetyltransferaseCurated (EC:2.3.1.-1 Publication)
Acetyl CoA:benzyl alcohol acetyltransferaseCurated (EC:2.3.1.2241 Publication)
Acetyl CoA:geraniol acetyltransferaseCurated (EC:2.3.1.-1 Publication)
Benzoyl coenzyme A:benzyl alcohol benzoyl transferase1 Publication
Short name:
Benzyl CoA:benzyl alcohol/phenylethanol benzoyltransferase1 Publication
Short name:
PhBPBT1 Publication
Benzyl CoA:(3Z)-hex-3-en-1-ol benzoyltransferaseCurated (EC:2.3.1.-1 Publication)
Benzyl CoA:2-phenylethanol benzoyltransferaseCurated (EC:2.3.1.-1 Publication)
Benzyl CoA:3-hydroxybenzyl alcohol benzoyltransferaseCurated (EC:2.3.1.-1 Publication)
Benzyl CoA:butanol benzoyltransferaseCurated (EC:2.3.1.-1 Publication)
Benzyl CoA:geraniol benzoyltransferaseCurated (EC:2.3.1.-1 Publication)
Benzyl CoA:octan-1-ol benzoyltransferaseCurated (EC:2.3.1.-1 Publication)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:BEBT11 Publication
Synonyms:BPBT1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPetunia hybrida (Petunia)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri4102 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaePetunioideaePetunia

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Decreased endogenous pool of benzoic acid (BA)/benzylbenzoate and lower methylbenzoate emission, but increased emission of benzyl alcohol and benzylaldehyde (PubMed:17194766, PubMed:20070567). Increase in the flux from cinnamic acid (CA) to coumaric acid and to flavonoids (PubMed:17194766). Delayed flowering time, large flowers and anthers, delayed anthesis, as well as large and dark seeds accumulating abnormal high levels of flavonoids and anthocyanins (PubMed:17194766). Greater internode length and stem diameter associated with an increased lignin accumulation (PubMed:17194766). Fewer first-order lateral branches but longer primary roots (PubMed:17194766). Seedlings exhibit epinastic cotyledons with fused or supernumerary cotyledons (PubMed:17194766). Increased auxin flux in roots (PubMed:17194766).2 Publications

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004515081 – 460Benzyl alcohol O-benzoyltransferaseAdd BLAST460

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Specifically expressed in flowers, mainly in the limb of flowers corollas, and, at low levels, in roots, stems, sepals and leaves.3 Publications

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

In corollas, accumulates progressively during flower development, from buds to anthesis, but fades out in senescing flowers.2 Publications

<p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Circadian-regulation with peak levels occurring during the night period (11 pm) in flowers.1 Publication

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q6E593

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the plant acyltransferase family.Curated

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.559.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR023213, CAT-like_dom_sf
IPR003480, Transferase

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02458, Transferase, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q6E593-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDSKQSSELV FTVRRQEPEL IAPAKPTPRE TKFLSDIDDQ EGLRFQIPVI
60 70 80 90 100
NFYRKDSSMG GKDPVEVIKK AIAETLVFYY PFAGRLREGN DRKLMVDCTG
110 120 130 140 150
EGVMFVEANA DVTLEEFGDE LQPPFPCLEE LLYDVPGSAG VLHCPLLLIQ
160 170 180 190 200
VTRLRCGGFI FALRLNHTMS DAPGLVQFMT AVGEMARGAT APSTLPVWCR
210 220 230 240 250
ELLNARNPPQ VTCTHHEYEE VPDTKGTLIP LDDMVHRSFF FGPTEVSALR
260 270 280 290 300
RFVPPHLHNC STFEVLTAAL WRCRTISIKP DPEEEVRVLC IVNARSRFNP
310 320 330 340 350
QLPSGYYGNA FAFPVAVTTA EKLCKNPLGY ALELVKKTKS DVTEEYMKSV
360 370 380 390 400
ADLMVIKGRP HFTVVRTYLV SDVTRAGFGE VDFGWGKAVY GGPAKGGVGA
410 420 430 440 450
IPGVASFYIP FRNKKGENGI VVPICLPGFA MEKFVKELDS MLKGDAQLDN
460
KKYAFITPAL
Length:460
Mass (Da):51,042
Last modified:August 16, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i04DF83A363A29D8B
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY563157 mRNA Translation: AAT68601.1
AY611496 mRNA Translation: AAU06226.1

Genome annotation databases

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ag:AAU06226

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY563157 mRNA Translation: AAT68601.1
AY611496 mRNA Translation: AAU06226.1

3D structure databases

SMRiQ6E593
ModBaseiSearch...

Genome annotation databases

KEGGiag:AAU06226

Enzyme and pathway databases

UniPathwayiUPA00739
BRENDAi2.3.1.196, 4700

Family and domain databases

Gene3Di3.30.559.10, 2 hits
InterProiView protein in InterPro
IPR023213, CAT-like_dom_sf
IPR003480, Transferase
PfamiView protein in Pfam
PF02458, Transferase, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiBEBT1_PETHY
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6E593
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 2, 2020
Last sequence update: August 16, 2004
Last modified: February 10, 2021
This is version 40 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again