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Entry version 105 (08 May 2019)
Sequence version 3 (10 May 2017)
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Protein

Protein CC2D2B

Gene

CC2D2B

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein CC2D2BCurated
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CC2D2BImported
Synonyms:C10orf130Imported, C10orf131Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:31666 CC2D2B

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q6DHV5

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000188649

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134931868
PA162381273

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
CC2D2B

Domain mapping of disease mutations (DMDM)

More...
DMDMi
109821270

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002440891 – 1058Protein CC2D2BAdd BLAST1058

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q6DHV5

PeptideAtlas

More...
PeptideAtlasi
Q6DHV5

PRoteomics IDEntifications database

More...
PRIDEi
Q6DHV5

ProteomicsDB human proteome resource

More...
ProteomicsDBi
66224
825

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q6DHV5

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q6DHV5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000188649 Expressed in 81 organ(s), highest expression level in testis

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q6DHV5 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q6DHV5 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA044091
HPA072122

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
136037, 2 interactors

Protein interaction database and analysis system

More...
IntActi
Q6DHV5, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000386988

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q6DHV5

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
KOG3639 Eukaryota
ENOG410XQVY LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000156590

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000111716

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q6DHV5

Identification of Orthologs from Complete Genome Data

More...
OMAi
SGSHPCW

Database of Orthologous Groups

More...
OrthoDBi
246535at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q6DHV5

TreeFam database of animal gene trees

More...
TreeFami
TF333815

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR041510 DUF5523

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF17661 DUF5523, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 6 potential isoforms that are computationally mapped.Show allAlign All

Isoform 3 (identifier: Q6DHV5-3) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MKKSQREDIF KKMSEEMDNI TAEEIIDKHL QKEENQNVAK TLRGKVREKL
60 70 80 90 100
KISKINKGEK SSTEQLIDSE IHQRSKTEVS LDESLSFFIL SGEEGSALGK
110 120 130 140 150
SSEQRPVNRS YPKCFSLGVN LQNVAESEEE EFMKEFILTD ILKVKAADYE
160 170 180 190 200
DDQEQIKKQK ANIFVPSSSP VVNQRKLPKD MMPRILEDEG FYIQRKPEIY
210 220 230 240 250
KKTCNKMENR LLKLEEGKCW FGESGEIMSL PTPIKQSWNF RLNVRKEPLN
260 270 280 290 300
PLLKTIYRKA VKYDLGSSFM NKMEGSREIY QLDLNIVGLQ FSHHHLFNQE
310 320 330 340 350
QVLCARLLQL YECFQDRQQQ NVSQLLYEKL KALTDATKLS NENSEINQLT
360 370 380 390 400
RKSLQDYYWQ ISNTKQMYDL ERGKDLSLLH SILRTWKQIK SLRHGQGFTS
410 420 430 440 450
TPIKLQVQRI KMNKCDEQEQ ISEMSETEKK NEGKELKNGK KLESLSYLAS
460 470 480 490 500
DETEIERIKP ITLRPQLSFT AELTSLSKCS FMLRNVDARS VPGIPWLMNE
510 520 530 540 550
QKLFEWANEV RIDPNNPEYS DLMESVTYMR LKGQDIPKYF RLEQLQDEFN
560 570 580 590 600
FVSEEEMAKS KRFQLLQLRN AGQLDNFLLQ QMPLHDTEIP DLVFQVRRLI
610 620 630 640 650
MKRIVKISKC NLSDIVNDYE EIVSTSQLTD AVCKFVEPRR KLKPQRKERK
660 670 680 690 700
KVTAQAISDG DIKILVRIVR AYNIPTRKTT INGSPGHDYS FSSLSKIKDN
710 720 730 740 750
IYINIFDEMM TEKHEISGTF QVTIPPVLLG YTWSNTYVFP KEDSNEQNLK
760 770 780 790 800
ECTFLNIFAT IEPQISYVTC NPTLDKFLDQ TEVLQRAQIF KKNCKAMFPN
810 820 830 840 850
RRIVTTVFND EGIQFLVTRY IKALNPPQQL LDIFLHNSNA TFDLIARFVS
860 870 880 890 900
LIPFVPNTPD ENDGSDIWMT SEHCISLAIG NKEEHAILLC NFFLYFGKKA
910 920 930 940 950
LVLLGTSVLE GHVAYVVTQE TNEYLLWNPS TGQCYKQFDP FCPLKSVDCL
960 970 980 990 1000
FDDRNVWFNI QQNNTPMAVF FDYSKESFWK QLLPKNVQGT KIQSIQVTGF
1010 1020 1030 1040 1050
PIQMPYIDVQ SIIDAVYQTG IHSAEFPQTE FALAVYIHPY PNNILSVWVY

LASLVQHQ
Length:1,058
Mass (Da):122,955
Last modified:May 10, 2017 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i97DEEFD9EFFC21C8
GO
Isoform 1 (identifier: Q6DHV5-1) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-736: Missing.
     737-776: YVFPKEDSNE...YVTCNPTLDK → MMTEKHEDHC...PFSALLQQSE

Show »
Length:322
Mass (Da):37,073
Checksum:iB375F2BA8D964585
GO
Isoform 2 (identifier: Q6DHV5-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-736: Missing.
     737-776: YVFPKEDSNE...YVTCNPTLDK → MMTEKHEDHC...PFSALLQQSE
     996-996: Q → QPEEIIYFET...EFERILQFYW

Note: No experimental confirmation available.
Show »
Length:401
Mass (Da):46,746
Checksum:iC8BB4456E6A63191
GO
Isoform 4 (identifier: Q6DHV5-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-12: MKKSQREDIFKK → MGVQ
     32-32: K → KDLDA
     76-76: K → KLSPQ
     171-176: VVNQRK → GNILSQ
     177-1058: Missing.

Show »
Length:176
Mass (Da):19,808
Checksum:i9765C52C1E321CD2
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A087WWB2A0A087WWB2_HUMAN
Protein CC2D2B
CC2D2B
176Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2R8Y8B5A0A2R8Y8B5_HUMAN
Protein CC2D2B
CC2D2B
1,429Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
R4GN90R4GN90_HUMAN
Protein CC2D2B
CC2D2B
61Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B7ZBX6B7ZBX6_HUMAN
Protein CC2D2B
CC2D2B
195Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1B0GUL2A0A1B0GUL2_HUMAN
Protein CC2D2B
CC2D2B
172Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1W2PQR2A0A1W2PQR2_HUMAN
Protein CC2D2B
CC2D2B
47Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Isoform 2 (identifier: Q6DHV5-2)
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti33S → P in BAG57652 (PubMed:14702039).1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_050697800N → D. Corresponds to variant dbSNP:rs17383738Ensembl.1
Natural variantiVAR_050698973Y → H. Corresponds to variant dbSNP:rs9943393Ensembl.1
Natural variantiVAR_0506991058Q → L. Corresponds to variant dbSNP:rs1336459Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0589341 – 736Missing in isoform 1 and isoform 2. Add BLAST736
Alternative sequenceiVSP_0589291 – 12MKKSQ…DIFKK → MGVQ in isoform 4. Add BLAST12
Alternative sequenceiVSP_05893032K → KDLDA in isoform 4. 1
Alternative sequenceiVSP_05893176K → KLSPQ in isoform 4. 1
Alternative sequenceiVSP_058932171 – 176VVNQRK → GNILSQ in isoform 4. 6
Alternative sequenceiVSP_058933177 – 1058Missing in isoform 4. Add BLAST882
Alternative sequenceiVSP_058935737 – 776YVFPK…PTLDK → MMTEKHEDHCLKSCSGHSYI RKNWLGCIVFPFSALLQQSE in isoform 1 and isoform 2. Add BLAST40
Alternative sequenceiVSP_044457996Q → QPEEIIYFETDKSMVEDLRN RIERTLKSKVMEWRPKHPTH WNRQCTFILRQILPKLEFGI GSFVSSEGDNEFERILQFYW in isoform 2. 1 Publication1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK294399 mRNA Translation: BAG57652.1
AK302377 mRNA Translation: BAG63696.1
AL356155 Genomic DNA No translation available.
AL365273 Genomic DNA No translation available.
AL513355 Genomic DNA No translation available.
BC075861 mRNA Translation: AAH75861.2

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS41555.1 [Q6DHV5-1]
CCDS53560.1 [Q6DHV5-2]
CCDS58090.1 [Q6DHV5-4]

NCBI Reference Sequences

More...
RefSeqi
NP_001001732.2, NM_001001732.3 [Q6DHV5-1]
NP_001123918.2, NM_001130446.2 [Q6DHV5-4]
NP_001153219.1, NM_001159747.1 [Q6DHV5-2]
XP_011538097.1, XM_011539795.2 [Q6DHV5-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000344386; ENSP00000343747; ENSG00000188649 [Q6DHV5-1]
ENST00000410012; ENSP00000386988; ENSG00000188649 [Q6DHV5-2]
ENST00000423344; ENSP00000411850; ENSG00000188649 [Q6DHV5-4]
ENST00000636965; ENSP00000490447; ENSG00000188649 [Q6DHV5-3]

Database of genes from NCBI RefSeq genomes

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GeneIDi
387707

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
hsa:387707

UCSC genome browser

More...
UCSCi
uc001kll.4 human [Q6DHV5-3]

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK294399 mRNA Translation: BAG57652.1
AK302377 mRNA Translation: BAG63696.1
AL356155 Genomic DNA No translation available.
AL365273 Genomic DNA No translation available.
AL513355 Genomic DNA No translation available.
BC075861 mRNA Translation: AAH75861.2
CCDSiCCDS41555.1 [Q6DHV5-1]
CCDS53560.1 [Q6DHV5-2]
CCDS58090.1 [Q6DHV5-4]
RefSeqiNP_001001732.2, NM_001001732.3 [Q6DHV5-1]
NP_001123918.2, NM_001130446.2 [Q6DHV5-4]
NP_001153219.1, NM_001159747.1 [Q6DHV5-2]
XP_011538097.1, XM_011539795.2 [Q6DHV5-2]

3D structure databases

SMRiQ6DHV5
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi136037, 2 interactors
IntActiQ6DHV5, 1 interactor
STRINGi9606.ENSP00000386988

PTM databases

iPTMnetiQ6DHV5
PhosphoSitePlusiQ6DHV5

Polymorphism and mutation databases

BioMutaiCC2D2B
DMDMi109821270

Proteomic databases

PaxDbiQ6DHV5
PeptideAtlasiQ6DHV5
PRIDEiQ6DHV5
ProteomicsDBi66224
825

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
387707
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000344386; ENSP00000343747; ENSG00000188649 [Q6DHV5-1]
ENST00000410012; ENSP00000386988; ENSG00000188649 [Q6DHV5-2]
ENST00000423344; ENSP00000411850; ENSG00000188649 [Q6DHV5-4]
ENST00000636965; ENSP00000490447; ENSG00000188649 [Q6DHV5-3]
GeneIDi387707
KEGGihsa:387707
UCSCiuc001kll.4 human [Q6DHV5-3]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
387707

GeneCards: human genes, protein and diseases

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GeneCardsi
CC2D2B
HGNCiHGNC:31666 CC2D2B
HPAiHPA044091
HPA072122
neXtProtiNX_Q6DHV5
OpenTargetsiENSG00000188649
PharmGKBiPA134931868
PA162381273

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3639 Eukaryota
ENOG410XQVY LUCA
GeneTreeiENSGT00940000156590
HOGENOMiHOG000111716
InParanoidiQ6DHV5
OMAiSGSHPCW
OrthoDBi246535at2759
PhylomeDBiQ6DHV5
TreeFamiTF333815

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
387707

Protein Ontology

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PROi
PR:Q6DHV5

Gene expression databases

BgeeiENSG00000188649 Expressed in 81 organ(s), highest expression level in testis
ExpressionAtlasiQ6DHV5 baseline and differential
GenevisibleiQ6DHV5 HS

Family and domain databases

InterProiView protein in InterPro
IPR041510 DUF5523
PfamiView protein in Pfam
PF17661 DUF5523, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiC2D2B_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6DHV5
Secondary accession number(s): A0A1B0GVB6
, A2A3E9, A6NCD4, B1AMZ2, B4DG41, B4DYD4, E9PCC3, Q5VUS0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: May 10, 2017
Last modified: May 8, 2019
This is version 105 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
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