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Protein
Submitted name:

Hepatitis A virus cellular receptor 1

Gene

havcr1

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  • apoptotic cell clearance Source: ZFIN
  • cytoskeletal rearrangement involved in phagocytosis, engulfment Source: ZFIN
  • engulfment of apoptotic cell Source: ZFIN

Names & Taxonomyi

Protein namesi
Submitted name:
Hepatitis A virus cellular receptor 1Imported
Submitted name:
Kidney injury molecule 1Imported
Submitted name:
Zgc:92647Imported
Gene namesi
Name:havcr1Imported
Synonyms:kim1Imported, zgc:92647Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 21

Organism-specific databases

ZFINiZDB-GENE-040718-131 havcr1

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei190 – 210HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_501509821123 – 264Sequence analysisAdd BLAST242

Expressioni

Gene expression databases

BgeeiENSDARG00000040178 Expressed in 17 organ(s), highest expression level in spleen

Structurei

3D structure databases

SMRiQ6DH50
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini31 – 113Ig-likeInterPro annotationAdd BLAST83

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

GeneTreeiENSGT00440000039800
HOGENOMiHOG000206336
TreeFamiTF336163

Family and domain databases

Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003599 Ig_sub
IPR013106 Ig_V-set
PfamiView protein in Pfam
PF07686 V-set, 1 hit
SMARTiView protein in SMART
SM00409 IG, 1 hit
SUPFAMiSSF48726 SSF48726, 1 hit
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

Q6DH50-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTDLHSWFLS SWILCCLTIC RCSDIIVQSF EGDNVTLPCK YDSRYHGKCE
60 70 80 90 100
ICWMRGDIPS RGCGEEIIAS DGDKVSTRNS DRYDLAGPIQ HGDVSLTIFN
110 120 130 140 150
IDKTDSGKYG CRVHVPGWFN DEKYYVHLIV DDDNKTRKEI SSTISPSYAP
160 170 180 190 200
RSSTAGMWLS NTTSVEPSVS VVYHESSSAE SKDNVTVSAV LVPVLLLLLA
210 220 230 240 250
LIAIAAAFMW KQKKKTRASL EVRQNSEISV IYSNSGSSVG LYNREMAVEN
260
VYQIQAESEY EQWH
Length:264
Mass (Da):29,575
Last modified:August 16, 2004 - v1
Checksum:i5674E3CF069D1AB0
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9QEV2E9QEV2_DANRE
Hepatitis A virus cellular receptor...
havcr1
293Annotation score:
A0A2R8QGQ2A0A2R8QGQ2_DANRE
Hepatitis A virus cellular receptor...
havcr1
324Annotation score:
F1QLX9F1QLX9_DANRE
Hepatitis A virus cellular receptor...
havcr1
280Annotation score:
E9QGJ4E9QGJ4_DANRE
Hepatitis A virus cellular receptor...
havcr1
291Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU463029 Genomic DNA No translation available.
BC076132 mRNA Translation: AAH76132.1
EF437151 mRNA Translation: ABP97434.1
CU638767 mRNA Translation: CAP71916.1
RefSeqiNP_001002434.1, NM_001002434.1
UniGeneiDr.29795

Genome annotation databases

EnsembliENSDART00000058774; ENSDARP00000058773; ENSDARG00000040178
GeneIDi436707
KEGGidre:436707

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU463029 Genomic DNA No translation available.
BC076132 mRNA Translation: AAH76132.1
EF437151 mRNA Translation: ABP97434.1
CU638767 mRNA Translation: CAP71916.1
RefSeqiNP_001002434.1, NM_001002434.1
UniGeneiDr.29795

3D structure databases

SMRiQ6DH50
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000058774; ENSDARP00000058773; ENSDARG00000040178
GeneIDi436707
KEGGidre:436707

Organism-specific databases

CTDi26762
ZFINiZDB-GENE-040718-131 havcr1

Phylogenomic databases

GeneTreeiENSGT00440000039800
HOGENOMiHOG000206336
TreeFamiTF336163

Gene expression databases

BgeeiENSDARG00000040178 Expressed in 17 organ(s), highest expression level in spleen

Family and domain databases

Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003599 Ig_sub
IPR013106 Ig_V-set
PfamiView protein in Pfam
PF07686 V-set, 1 hit
SMARTiView protein in SMART
SM00409 IG, 1 hit
SUPFAMiSSF48726 SSF48726, 1 hit
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ6DH50_DANRE
AccessioniPrimary (citable) accession number: Q6DH50
Entry historyiIntegrated into UniProtKB/TrEMBL: August 16, 2004
Last sequence update: August 16, 2004
Last modified: November 7, 2018
This is version 122 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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