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Protein

Pre-mRNA-splicing factor syf2

Gene

syf2

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Involved in pre-mRNA splicing as component of the spliceosome.By similarity

GO - Biological processi

Keywordsi

Biological processmRNA processing, mRNA splicing

Enzyme and pathway databases

ReactomeiR-DRE-72163 mRNA Splicing - Major Pathway

Names & Taxonomyi

Protein namesi
Recommended name:
Pre-mRNA-splicing factor syf2
Gene namesi
Name:syf2
ORF Names:zgc:92835
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 13

Organism-specific databases

ZFINiZDB-GENE-040801-170 syf2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus, Spliceosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002503791 – 238Pre-mRNA-splicing factor syf2Add BLAST238

Proteomic databases

PaxDbiQ6DGP2

Expressioni

Gene expression databases

BgeeiENSDARG00000004706 Expressed in 33 organ(s), highest expression level in testis

Interactioni

Subunit structurei

Identified in the spliceosome C complex.By similarity

Protein-protein interaction databases

STRINGi7955.ENSDARP00000090723

Structurei

3D structure databases

SMRiQ6DGP2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili64 – 85Sequence analysisAdd BLAST22

Sequence similaritiesi

Belongs to the SYF2 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiKOG2609 Eukaryota
ENOG410XY86 LUCA
GeneTreeiENSGT00390000017845
HOGENOMiHOG000190170
HOVERGENiHBG080129
InParanoidiQ6DGP2
KOiK12868
OMAiRRRMHND
OrthoDBiEOG091G0MY0
PhylomeDBiQ6DGP2
TreeFamiTF313041

Family and domain databases

InterProiView protein in InterPro
IPR013260 mRNA_splic_SYF2
PANTHERiPTHR13264 PTHR13264, 1 hit
PfamiView protein in Pfam
PF08231 SYF2, 1 hit

Sequencei

Sequence statusi: Complete.

Q6DGP2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASSEEVVAP SNEEEVTETP AAQKREERLR KFRELHFKRN EARKLNHQEV
60 70 80 90 100
VEEDKRLKLP SNWEAKKARL EYELLVDQKK KECAERGEDY DRVKLLEISA
110 120 130 140 150
EDAERWERKK KKRNPDPGFS GYAEAQLRQY QRLTKQIKPD MENYEKQKEE
160 170 180 190 200
CGEDFHPTSN SLIYGTHVPS KDSINRMVDD VEKQIEKRAK YSRRRAYNDD
210 220 230
ADIDYINERN AKFNKKAERF YGKYTAEIKQ NLERGTAV
Length:238
Mass (Da):28,309
Last modified:August 16, 2004 - v1
Checksum:i620F2EC575361CBA
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti108R → G in AAH91556 (Ref. 1) Curated1
Sequence conflicti148K → R in AAH91556 (Ref. 1) Curated1
Sequence conflicti150E → D in AAH91556 (Ref. 1) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC076298 mRNA Translation: AAH76298.1
BC091556 mRNA Translation: AAH91556.1
RefSeqiNP_001003437.1, NM_001003437.2
UniGeneiDr.75653

Genome annotation databases

EnsembliENSDART00000099950; ENSDARP00000090723; ENSDARG00000004706
GeneIDi445043
KEGGidre:445043

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC076298 mRNA Translation: AAH76298.1
BC091556 mRNA Translation: AAH91556.1
RefSeqiNP_001003437.1, NM_001003437.2
UniGeneiDr.75653

3D structure databases

SMRiQ6DGP2
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000090723

Proteomic databases

PaxDbiQ6DGP2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000099950; ENSDARP00000090723; ENSDARG00000004706
GeneIDi445043
KEGGidre:445043

Organism-specific databases

CTDi25949
ZFINiZDB-GENE-040801-170 syf2

Phylogenomic databases

eggNOGiKOG2609 Eukaryota
ENOG410XY86 LUCA
GeneTreeiENSGT00390000017845
HOGENOMiHOG000190170
HOVERGENiHBG080129
InParanoidiQ6DGP2
KOiK12868
OMAiRRRMHND
OrthoDBiEOG091G0MY0
PhylomeDBiQ6DGP2
TreeFamiTF313041

Enzyme and pathway databases

ReactomeiR-DRE-72163 mRNA Splicing - Major Pathway

Miscellaneous databases

PROiPR:Q6DGP2

Gene expression databases

BgeeiENSDARG00000004706 Expressed in 33 organ(s), highest expression level in testis

Family and domain databases

InterProiView protein in InterPro
IPR013260 mRNA_splic_SYF2
PANTHERiPTHR13264 PTHR13264, 1 hit
PfamiView protein in Pfam
PF08231 SYF2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiSYF2_DANRE
AccessioniPrimary (citable) accession number: Q6DGP2
Secondary accession number(s): Q5BJA7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 19, 2006
Last sequence update: August 16, 2004
Last modified: September 12, 2018
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health

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