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Protein
Submitted name:

MGC83523 protein

Gene

pla2g6

Organism
Xenopus laevis (African clawed frog)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei469NucleophilePROSITE-ProRule annotation1
Active sitei602Proton acceptorPROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolasePROSITE-ProRule annotation
Biological processLipid degradationPROSITE-ProRule annotation, Lipid metabolism

Names & Taxonomyi

Protein namesi
Submitted name:
MGC83523 proteinImported
Gene namesi
Name:pla2g6Imported
Synonyms:MGC83523Imported
OrganismiXenopus laevis (African clawed frog)Imported
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Organism-specific databases

XenbaseiXB-GENE-920454 pla2g6

Structurei

3D structure databases

ProteinModelPortaliQ6DDK0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini151 – 392ANK_REP_REGIONInterPro annotationAdd BLAST242
Repeati151 – 184ANKPROSITE-ProRule annotationAdd BLAST34
Repeati219 – 251ANKPROSITE-ProRule annotationAdd BLAST33
Repeati349 – 381ANKPROSITE-ProRule annotationAdd BLAST33
Domaini431 – 615PNPLAInterPro annotationAdd BLAST185

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili165 – 185Sequence analysisAdd BLAST21

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi435 – 440GXGXXGPROSITE-ProRule annotation6
Motifi467 – 471GXSXGPROSITE-ProRule annotation5
Motifi602 – 604DGA/GPROSITE-ProRule annotation3

Keywords - Domaini

ANK repeatPROSITE-ProRule annotation, Coiled coilSequence analysis

Phylogenomic databases

HOVERGENiHBG053482
KOiK16343

Family and domain databases

CDDicd00204 ANK, 2 hits
Gene3Di1.25.40.20, 2 hits
InterProiView protein in InterPro
IPR016035 Acyl_Trfase/lysoPLipase
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR002641 PNPLA_dom
PfamiView protein in Pfam
PF12796 Ank_2, 2 hits
PF01734 Patatin, 1 hit
PRINTSiPR01415 ANKYRIN
SMARTiView protein in SMART
SM00248 ANK, 7 hits
SUPFAMiSSF48403 SSF48403, 1 hit
SSF52151 SSF52151, 1 hit
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 3 hits
PS51635 PNPLA, 1 hit

Sequencei

Sequence statusi: Complete.

Q6DDK0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDLFGRIFNT VSAVTNLFSN PYKVREVPLS EYGSSSCLQE DGRMLLYRNR
60 70 80 90 100
TAKSLDCVLV NPSSPQNAYR LFQLESEPEA LCRFQEYAVK LRPFYESSRK
110 120 130 140 150
GLCLETLQQL TDCIRSHPNW SLAHVAVEIG LRESFKHNGI LRSLNSTECD
160 170 180 190 200
GGSTPLHLAC KKGDINCLQE LVEECQARLD IADQNGETVY HHAAQQNNPR
210 220 230 240 250
VIEILCSVPS VGVNHKSNNN ETPLHVACRL GKTELVLALL RCHARCDIIG
260 270 280 290 300
KDGYPIHTAM KYSQKECVEA ILDVSASQLH AEDPRYQATP IHWAKNAEMA
310 320 330 340 350
RLLIERGCNV NTCSKTLDTP LHIMVKRDRF EAAMVLLTNV ADPNVKGEHG
360 370 380 390 400
NTPLHLAMKK DQLELIKALM VFGADVEQHN DFGETPGLIA ARSSKGFRDF
410 420 430 440 450
VYVSTALSGM LVPQDTVDFR EDGLRVKDRL LCLDGGGIRG LVLMQLLIAI
460 470 480 490 500
EKAAGRPIRE LFDWVSGTST GGILALAIVH GMPMESVRCL YFRMKNEVFH
510 520 530 540 550
GSRPYESGPL EEFLKKEFGE NTKMSDVRNP KVIVTGTLSD RHPAELHLFR
560 570 580 590 600
NYDPPETDHE PPYKSVASFR PVTTPAEQLV WHAARSSGAA PTYLRPMGRF
610 620 630 640 650
LDGGLLSNNP TLDAMTEIHE YNTCLKKKGM AGQVKKLGIV VSLGTGKPPQ
660 670 680 690 700
ISVGSVDVFR PSNPWEVMKT VVGARELGKM VVDCCTDSDG PAVSRARAWC
710 720 730 740 750
EMIDVPYFRL SPQLQTDVML DEVSDAVLVN MLWDTQIYIY QQREVLQRLA

KTLLEP
Length:756
Mass (Da):84,304
Last modified:August 16, 2004 - v1
Checksum:iC0278741CCA52A71
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC077558 mRNA Translation: AAH77558.1
RefSeqiNP_001086854.1, NM_001093385.1
UniGeneiXl.48378

Genome annotation databases

GeneIDi446689
KEGGixla:446689

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC077558 mRNA Translation: AAH77558.1
RefSeqiNP_001086854.1, NM_001093385.1
UniGeneiXl.48378

3D structure databases

ProteinModelPortaliQ6DDK0
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi446689
KEGGixla:446689

Organism-specific databases

CTDi446689
XenbaseiXB-GENE-920454 pla2g6

Phylogenomic databases

HOVERGENiHBG053482
KOiK16343

Family and domain databases

CDDicd00204 ANK, 2 hits
Gene3Di1.25.40.20, 2 hits
InterProiView protein in InterPro
IPR016035 Acyl_Trfase/lysoPLipase
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR002641 PNPLA_dom
PfamiView protein in Pfam
PF12796 Ank_2, 2 hits
PF01734 Patatin, 1 hit
PRINTSiPR01415 ANKYRIN
SMARTiView protein in SMART
SM00248 ANK, 7 hits
SUPFAMiSSF48403 SSF48403, 1 hit
SSF52151 SSF52151, 1 hit
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 3 hits
PS51635 PNPLA, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ6DDK0_XENLA
AccessioniPrimary (citable) accession number: Q6DDK0
Entry historyiIntegrated into UniProtKB/TrEMBL: August 16, 2004
Last sequence update: August 16, 2004
Last modified: May 23, 2018
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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