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Protein

DnaJ homolog subfamily C member 15

Gene

dnajc15

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Negative regulator of the mitochondrial respiratory chain (By similarity). Plays a role in the translocation of proteins across the mitochondrial inner membrane (By similarity). Involved in pronephric kidney development at the early tadpole stage.By similarity1 Publication

GO - Biological processi

  • pronephros development Source: UniProtKB
  • protein transport Source: UniProtKB-KW

Keywordsi

Molecular functionDevelopmental protein
Biological processProtein transport, Translocation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
DnaJ homolog subfamily C member 15By similarity
Gene namesi
Name:dnajc15Imported
OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Taxonomic identifieri8364 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana
Proteomesi
  • UP000008143 Componenti: Unassembled WGS sequence

Organism-specific databases

XenbaseiXB-GENE-5716026 dnajc15

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 34Mitochondrial intermembraneSequence analysisAdd BLAST34
Transmembranei35 – 57HelicalSequence analysisAdd BLAST23
Topological domaini58 – 149Mitochondrial matrixSequence analysisAdd BLAST92

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003916881 – 149DnaJ homolog subfamily C member 15Add BLAST149

Proteomic databases

PaxDbiQ6DDA1

Expressioni

Tissue specificityi

Expressed in the developing pronephros.1 Publication

Gene expression databases

BgeeiENSXETG00000014585

Interactioni

Protein-protein interaction databases

STRINGi8364.ENSXETP00000031900

Structurei

3D structure databases

ProteinModelPortaliQ6DDA1
SMRiQ6DDA1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini95 – 149JPROSITE-ProRule annotationAdd BLAST55

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0723 Eukaryota
COG2214 LUCA
GeneTreeiENSGT00390000017303
HOGENOMiHOG000115841
HOVERGENiHBG057483
InParanoidiQ6DDA1
KOiK09535
OMAiRYAFHLW
OrthoDBiEOG091G116P
TreeFamiTF320584

Family and domain databases

CDDicd06257 DnaJ, 1 hit
Gene3Di1.10.287.110, 1 hit
InterProiView protein in InterPro
IPR001623 DnaJ_domain
IPR036869 J_dom_sf
PfamiView protein in Pfam
PF00226 DnaJ, 1 hit
SMARTiView protein in SMART
SM00271 DnaJ, 1 hit
SUPFAMiSSF46565 SSF46565, 1 hit
PROSITEiView protein in PROSITE
PS50076 DNAJ_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q6DDA1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATSSTGMGT SEALRYSEYM PGPNAGSSTD IDRRLGGTLI AVGLGVAAAA
60 70 80 90 100
FAGRFAFQLW KPLGQVIAES AKKIPTPSLS YYYKGGFEQK MNRREASLIL
110 120 130 140
GVSPSASKSK IRAAHRKIMI LNHPDKGGSP YMAMKINEAK DLLESTTKP
Length:149
Mass (Da):15,941
Last modified:August 16, 2004 - v1
Checksum:iD89D77FEE78288D5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC077694 mRNA Translation: AAH77694.1
RefSeqiNP_001005145.1, NM_001005145.2
UniGeneiStr.3623

Genome annotation databases

EnsembliENSXETT00000031900; ENSXETP00000031900; ENSXETG00000014585
GeneIDi448735
KEGGixtr:448735

Similar proteinsi

Entry informationi

Entry nameiDJC15_XENTR
AccessioniPrimary (citable) accession number: Q6DDA1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 2, 2010
Last sequence update: August 16, 2004
Last modified: February 28, 2018
This is version 87 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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