UniProtKB - Q6DBS2 (Q6DBS2_DANRE)
Protein
Submitted name:
Distal-less homeobox gene 3b
Gene
dlx3b
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Functioni
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
DNA bindingi | 125 – 184 | HomeoboxPROSITE-ProRule annotationAdd BLAST | 60 |
GO - Molecular functioni
- DNA binding Source: UniProtKB-UniRule
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: InterPro
Keywordsi
Molecular function | DNA-bindingPROSITE-ProRule annotationImportedARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Distal-less homeobox gene 3bImportedSubmitted name: Dlx3b proteinImportedSubmitted name: Homeobox protein Dlx3bImported |
Gene namesi | Name:dlx3bImported |
Organismi | Danio rerio (Zebrafish) (Brachydanio rerio)Imported |
Taxonomic identifieri | 7955 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Danionidae › Danioninae › Danio |
Proteomesi |
|
Organism-specific databases
ZFINi | ZDB-GENE-980526-280, dlx3b |
Subcellular locationi
Keywords - Cellular componenti
NucleusPROSITE-ProRule annotationARBA annotationExpressioni
Gene expression databases
Bgeei | ENSDARG00000014626, Expressed in zone of skin and 80 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 123 – 183 | HomeoboxInterPro annotationAdd BLAST | 61 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 41 | DisorderedSequence analysisAdd BLAST | 41 | |
Regioni | 191 – 242 | DisorderedSequence analysisAdd BLAST | 52 | |
Regioni | 250 – 269 | DisorderedSequence analysisAdd BLAST | 20 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 15 – 41 | PolarSequence analysisAdd BLAST | 27 | |
Compositional biasi | 197 – 228 | PolarSequence analysisAdd BLAST | 32 |
Sequence similaritiesi
Belongs to the distal-less homeobox family.ARBA annotation
Keywords - Domaini
HomeoboxPROSITE-ProRule annotationImportedARBA annotationPhylogenomic databases
GeneTreei | ENSGT00940000158951 |
HOGENOMi | CLU_074733_1_0_1 |
OMAi | EDYNNHW |
OrthoDBi | 1416398at2759 |
TreeFami | TF350606 |
Family and domain databases
CDDi | cd00086, homeodomain, 1 hit |
InterProi | View protein in InterPro IPR022135, Distal-less_N IPR009057, Homeobox-like_sf IPR017970, Homeobox_CS IPR001356, Homeobox_dom IPR020479, Homeobox_metazoa IPR000047, HTH_motif |
Pfami | View protein in Pfam PF12413, DLL_N, 1 hit PF00046, Homeodomain, 1 hit |
PRINTSi | PR00024, HOMEOBOX PR00031, HTHREPRESSR |
SMARTi | View protein in SMART SM00389, HOX, 1 hit |
SUPFAMi | SSF46689, SSF46689, 1 hit |
PROSITEi | View protein in PROSITE PS00027, HOMEOBOX_1, 1 hit PS50071, HOMEOBOX_2, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
Q6DBS2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSGPTYDRKI PGISTDLSGS MSCHPTSKDS PTLPESSATD MGYYSSHHEY
60 70 80 90 100
YQSPPYPQQM NSYHQFNLSG MGATPGAYPT KTEYPYNTYR QYGHYNRDLQ
110 120 130 140 150
TPPQSAVKEE PETEVRMVNG KPKKIRKPRT IYSSYQLAAL QRRFQKAQYL
160 170 180 190 200
ALPERAELAA QLGLTQTQVK IWFQNRRSKF KKLYKNGEVP LEHSPNASDS
210 220 230 240 250
MACNSPPSPA VWDNNAHSSQ VNRGQIPQPP LSSTPPYMED YSNHWYQQGS
260
HLQHPVHHPG PPQSVGAVY
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketQ01702 | DLX3B_DANRE | Homeobox protein Dlx3b | dlx3b dlx3 | 269 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU468219 Genomic DNA No translation available. BC078386 mRNA Translation: AAH78386.1 BC163992 mRNA Translation: AAI63992.1 |
RefSeqi | NP_571397.2, NM_131322.2 |
Genome annotation databases
Ensembli | ENSDART00000017191; ENSDARP00000022291; ENSDARG00000014626 |
GeneIDi | 30585 |
KEGGi | dre:30585 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU468219 Genomic DNA No translation available. BC078386 mRNA Translation: AAH78386.1 BC163992 mRNA Translation: AAI63992.1 |
RefSeqi | NP_571397.2, NM_131322.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protocols and materials databases
DNASUi | 30585 |
Genome annotation databases
Ensembli | ENSDART00000017191; ENSDARP00000022291; ENSDARG00000014626 |
GeneIDi | 30585 |
KEGGi | dre:30585 |
Organism-specific databases
CTDi | 30585 |
ZFINi | ZDB-GENE-980526-280, dlx3b |
Phylogenomic databases
GeneTreei | ENSGT00940000158951 |
HOGENOMi | CLU_074733_1_0_1 |
OMAi | EDYNNHW |
OrthoDBi | 1416398at2759 |
TreeFami | TF350606 |
Gene expression databases
Bgeei | ENSDARG00000014626, Expressed in zone of skin and 80 other tissues |
Family and domain databases
CDDi | cd00086, homeodomain, 1 hit |
InterProi | View protein in InterPro IPR022135, Distal-less_N IPR009057, Homeobox-like_sf IPR017970, Homeobox_CS IPR001356, Homeobox_dom IPR020479, Homeobox_metazoa IPR000047, HTH_motif |
Pfami | View protein in Pfam PF12413, DLL_N, 1 hit PF00046, Homeodomain, 1 hit |
PRINTSi | PR00024, HOMEOBOX PR00031, HTHREPRESSR |
SMARTi | View protein in SMART SM00389, HOX, 1 hit |
SUPFAMi | SSF46689, SSF46689, 1 hit |
PROSITEi | View protein in PROSITE PS00027, HOMEOBOX_1, 1 hit PS50071, HOMEOBOX_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q6DBS2_DANRE | |
Accessioni | Q6DBS2Primary (citable) accession number: Q6DBS2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | August 16, 2004 |
Last sequence update: | August 16, 2004 | |
Last modified: | December 2, 2020 | |
This is version 144 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |