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UniProtKB - Q6CXR8 (PAM17_KLULA)
Protein
Presequence translocated-associated motor subunit PAM17, mitochondrial
Gene
PAM17
Organism
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)
Status
Functioni
Component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
By similarityGO - Biological processi
- protein import into mitochondrial matrix Source: EnsemblFungi
Keywordsi
Biological process | Protein transport, Translocation, Transport |
Names & Taxonomyi
Protein namesi | Recommended name: Presequence translocated-associated motor subunit PAM17, mitochondrial |
Gene namesi | Name:PAM17 Ordered Locus Names:KLLA0A06083g |
Organismi | Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica) |
Taxonomic identifieri | 284590 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Kluyveromyces › |
Proteomesi |
|
Subcellular locationi
Mitochondrion
- Mitochondrion inner membrane By similarity; Multi-pass membrane protein By similarity
Mitochondrion
- PAM complex, Tim23 associated import motor Source: EnsemblFungi
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 68 – 88 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 106 – 126 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
Membrane, Mitochondrion, Mitochondrion inner membranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transit peptidei | 1 – 33 | MitochondrionSequence analysisAdd BLAST | 33 | |
ChainiPRO_0000043157 | 34 – 196 | Presequence translocated-associated motor subunit PAM17, mitochondrialAdd BLAST | 163 |
Interactioni
Subunit structurei
Component of the PAM complex, at least composed of mtHsp70 (SSC1), MGE1, TIM44, PAM16, PAM17 and PAM18.
By similarityProtein-protein interaction databases
STRINGi | 28985.XP_451271.1 |
Structurei
3D structure databases
AlphaFoldDBi | Q6CXR8 |
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Family & Domainsi
Sequence similaritiesi
Belongs to the PAM17 family.Curated
Keywords - Domaini
Transit peptide, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | ENOG502S1B1, Eukaryota |
HOGENOMi | CLU_068297_2_0_1 |
InParanoidi | Q6CXR8 |
OMAi | YKPSVNT |
Family and domain databases
InterProi | View protein in InterPro IPR013875, Pam17 |
PANTHERi | PTHR28021, PTHR28021, 1 hit |
Pfami | View protein in Pfam PF08566, Pam17, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
Q6CXR8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLRLGINLQN RLLVGLNGQS LLKRAVTRNA VAIRMNSTNA GKTASHEMTW
60 70 80 90 100
PEFFKLRKKE RVFNTASSVA TAIVFVNGSW FYFSTLEIDP TQTIFGFDPL
110 120 130 140 150
MAITAGMITC AAVGWLLGPI VGTALFKATS GPKLLQFQEK QLSFLAKIQK
160 170 180 190
NRVNPQSQSF SNPVPDYYGE KINSIPQYRQ WLRDCHSYKR KASEFL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CR382121 Genomic DNA Translation: CAH02859.1 |
RefSeqi | XP_451271.1, XM_451271.1 |
Genome annotation databases
EnsemblFungii | CAH02859; CAH02859; KLLA0_A06083g |
GeneIDi | 2896450 |
KEGGi | kla:KLLA0_A06083g |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CR382121 Genomic DNA Translation: CAH02859.1 |
RefSeqi | XP_451271.1, XM_451271.1 |
3D structure databases
AlphaFoldDBi | Q6CXR8 |
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 28985.XP_451271.1 |
Genome annotation databases
EnsemblFungii | CAH02859; CAH02859; KLLA0_A06083g |
GeneIDi | 2896450 |
KEGGi | kla:KLLA0_A06083g |
Phylogenomic databases
eggNOGi | ENOG502S1B1, Eukaryota |
HOGENOMi | CLU_068297_2_0_1 |
InParanoidi | Q6CXR8 |
OMAi | YKPSVNT |
Family and domain databases
InterProi | View protein in InterPro IPR013875, Pam17 |
PANTHERi | PTHR28021, PTHR28021, 1 hit |
Pfami | View protein in Pfam PF08566, Pam17, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | PAM17_KLULA | |
Accessioni | Q6CXR8Primary (citable) accession number: Q6CXR8 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | December 6, 2005 |
Last sequence update: | August 16, 2004 | |
Last modified: | May 25, 2022 | |
This is version 84 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families