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Protein

Nucleolar protein 58

Gene

NOP58

Organism
Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Required for pre-18S rRNA processing. May bind microtubules (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein
Biological processRibosome biogenesis, rRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Nucleolar protein 58
Gene namesi
Name:NOP58
Ordered Locus Names:YALI0B00946g
OrganismiYarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)
Taxonomic identifieri284591 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDipodascaceaeYarrowia
Proteomesi
  • UP000001300 Componenti: Chromosome B

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003509951 – 515Nucleolar protein 58Add BLAST515

Interactioni

Protein-protein interaction databases

STRINGi4952.XP_500366.1

Structurei

3D structure databases

ProteinModelPortaliQ6CG46
SMRiQ6CG46
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini283 – 403NopPROSITE-ProRule annotationAdd BLAST121

Sequence similaritiesi

Belongs to the NOP5/NOP56 family.Curated

Phylogenomic databases

HOGENOMiHOG000196310
InParanoidiQ6CG46
KOiK14565
OMAiDINQFAM
OrthoDBiEOG092C3GG0

Family and domain databases

Gene3Di1.10.287.660, 2 hits
InterProiView protein in InterPro
IPR029012 Helix_hairpin_bin_sf
IPR012974 NOP5_N
IPR002687 Nop_dom
IPR036070 Nop_dom_sf
IPR012976 NOSIC
PfamiView protein in Pfam
PF01798 Nop, 1 hit
PF08156 NOP5NT, 1 hit
SMARTiView protein in SMART
SM00931 NOSIC, 1 hit
SUPFAMiSSF89124 SSF89124, 1 hit
PROSITEiView protein in PROSITE
PS51358 NOP, 1 hit

Sequencei

Sequence statusi: Complete.

Q6CG46-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTFILTETSA GYAVLKAKDK KIYKSESILE ELSTPELVTS QFKVKGFSKF
60 70 80 90 100
DSAASALEEV NAIVDGRVSD KLAALLNEFK DEKKSALVVA DPKLGNAINK
110 120 130 140 150
LDLPFDVVAE SASLDLFRAI RENLPSLLPG LTEKDLATMS LGLAHSLGRH
160 170 180 190 200
KLKFSPDKVD TMIVQAIALL DDLDKELNTY AMRIKEWYGW HFPEMAKIVA
210 220 230 240 250
DNIAYARVIK TMGYRSNASE TDLSEVLPEE VEAALKVAAE VSMGTEITEF
260 270 280 290 300
DLENIQCLAD QVIDFAEYRE QLSNYLNARM AAIAPNLTAL VGELVGARLI
310 320 330 340 350
AHSGSLVNLA KAPASTVQIL GAEKALFRAL KTKHDTPKYG IIYHASLIGQ
360 370 380 390 400
ASGKNKGKIA RMLAAKASVS MRYDAFAEER EDVPILGIDN RIKVENRLRQ
410 420 430 440 450
LEGKEIVGTV RPDVNKIEHK KVDLSTGKQY NADADTVGNT TAGADSDDED
460 470 480 490 500
SDSEEEVKEK KAKKEKKEKK DKKEKKDKKD KKEKKDKKEK KEKKDKKRKR
510
EDDDDEPKKE KKSKK
Length:515
Mass (Da):57,234
Last modified:August 16, 2004 - v1
Checksum:iFC1426596D3F7326
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR382128 Genomic DNA Translation: CAG82580.1
RefSeqiXP_500366.1, XM_500366.1

Genome annotation databases

EnsemblFungiiCAG82580; CAG82580; YALI0_B00946g
GeneIDi2907148
KEGGiyli:YALI0B00946g

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR382128 Genomic DNA Translation: CAG82580.1
RefSeqiXP_500366.1, XM_500366.1

3D structure databases

ProteinModelPortaliQ6CG46
SMRiQ6CG46
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi4952.XP_500366.1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCAG82580; CAG82580; YALI0_B00946g
GeneIDi2907148
KEGGiyli:YALI0B00946g

Phylogenomic databases

HOGENOMiHOG000196310
InParanoidiQ6CG46
KOiK14565
OMAiDINQFAM
OrthoDBiEOG092C3GG0

Family and domain databases

Gene3Di1.10.287.660, 2 hits
InterProiView protein in InterPro
IPR029012 Helix_hairpin_bin_sf
IPR012974 NOP5_N
IPR002687 Nop_dom
IPR036070 Nop_dom_sf
IPR012976 NOSIC
PfamiView protein in Pfam
PF01798 Nop, 1 hit
PF08156 NOP5NT, 1 hit
SMARTiView protein in SMART
SM00931 NOSIC, 1 hit
SUPFAMiSSF89124 SSF89124, 1 hit
PROSITEiView protein in PROSITE
PS51358 NOP, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiNOP58_YARLI
AccessioniPrimary (citable) accession number: Q6CG46
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 23, 2008
Last sequence update: August 16, 2004
Last modified: March 28, 2018
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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