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Protein

Mitochondrial import inner membrane translocase subunit TIM44

Gene

DEHA2C05962g

Organism
Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processProtein transport, TranslocationUniRule annotation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Mitochondrial import inner membrane translocase subunit TIM44UniRule annotation
Gene namesi
Ordered Locus Names:DEHA2C05962gImported
OrganismiDebaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii)Imported
Taxonomic identifieri284592 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeDebaryomyces
Proteomesi
  • UP000000599 Componenti: Chromosome C

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membraneUniRule annotation

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliQ6BV22
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini267 – 421Tim44InterPro annotationAdd BLAST155

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili51 – 71Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the Tim44 family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

HOGENOMiHOG000208172
InParanoidiQ6BV22
KOiK17804
OMAiRFLKQCE
OrthoDBiEOG092C2GAN

Family and domain databases

InterProiView protein in InterPro
IPR032710 NTF2-like_dom_sf
IPR017303 Tim44
IPR039544 Tim44-like
IPR007379 Tim44-like_dom
PANTHERiPTHR10721 PTHR10721, 1 hit
PfamiView protein in Pfam
PF04280 Tim44, 1 hit
PIRSFiPIRSF037871 TIM44, 1 hit
SMARTiView protein in SMART
SM00978 Tim44, 1 hit
SUPFAMiSSF54427 SSF54427, 1 hit

Sequencei

Sequence statusi: Complete.

Q6BV22-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLRSNIIKNA TNYQTQILKS STTSQIRLFH NSQIHYNERP QSPLKVFFDT
60 70 80 90 100
FKAEVKKSNE LKENIKALQD ESGRVADSEA FRKAKEAFDK AQKGSSAAGK
110 120 130 140 150
VAKKTAHVVG GAAYKAWESP VGKGVRTSVR TSAEAADKAF DPVRNTTVYK
160 170 180 190 200
NVSDVIDDGS SNSYGGFLTK EQRQKLREKE LAEKLRSGKV WKPVKEDESA
210 220 230 240 250
GGALIATEHK ASGPTMSDKW ENFKVKSPIG RAIVILREKW DDSENGLISL
260 270 280 290 300
VRTIIEKVTG FFAETEQAKV IKQFKQMDPA FRVTDFTKTL TNYIVPELLD
310 320 330 340 350
SYIKNDEKVL KHWFSEAPFN VWQANNKQFI QQGLFSDGKI LDIRGVDIVT
360 370 380 390 400
CKSLQPNDIP VIVVSCRAQE IHLYRKAKTG EIAAGTEDHI QLSTYAMVFT
410 420
RIPEEFDNTV TEGWKVIEFA RGGSRPFH
Length:428
Mass (Da):48,090
Last modified:August 16, 2004 - v1
Checksum:i787F3EFC42773136
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR382135 Genomic DNA Translation: CAG86003.1
RefSeqiXP_457947.1, XM_457947.1

Genome annotation databases

EnsemblFungiiCAG86003; CAG86003; DEHA2C05962g
GeneIDi2900820
KEGGidha:DEHA2C05962g

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR382135 Genomic DNA Translation: CAG86003.1
RefSeqiXP_457947.1, XM_457947.1

3D structure databases

ProteinModelPortaliQ6BV22
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCAG86003; CAG86003; DEHA2C05962g
GeneIDi2900820
KEGGidha:DEHA2C05962g

Phylogenomic databases

HOGENOMiHOG000208172
InParanoidiQ6BV22
KOiK17804
OMAiRFLKQCE
OrthoDBiEOG092C2GAN

Family and domain databases

InterProiView protein in InterPro
IPR032710 NTF2-like_dom_sf
IPR017303 Tim44
IPR039544 Tim44-like
IPR007379 Tim44-like_dom
PANTHERiPTHR10721 PTHR10721, 1 hit
PfamiView protein in Pfam
PF04280 Tim44, 1 hit
PIRSFiPIRSF037871 TIM44, 1 hit
SMARTiView protein in SMART
SM00978 Tim44, 1 hit
SUPFAMiSSF54427 SSF54427, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ6BV22_DEBHA
AccessioniPrimary (citable) accession number: Q6BV22
Entry historyiIntegrated into UniProtKB/TrEMBL: August 16, 2004
Last sequence update: August 16, 2004
Last modified: November 7, 2018
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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