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Entry version 129 (05 Jun 2019)
Sequence version 1 (13 Sep 2004)
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Protein

Fc receptor-like B

Gene

FCRLB

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Fc receptor-like B
Alternative name(s):
Fc receptor homolog expressed in B-cells protein 2
Short name:
FREB-2
Fc receptor-like and mucin-like protein 2
Fc receptor-like protein 2
Fc receptor-related protein Y
Short name:
FcRY
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:FCRLB
Synonyms:FCRL2, FCRLM2, FCRY, FREB2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:26431 FCRLB

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
609251 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q6BAA4

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm, Endoplasmic reticulum

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
127943

Open Targets

More...
OpenTargetsi
ENSG00000162746

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162388195

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
FCRLB

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74757430

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 17Sequence analysisAdd BLAST17
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000033299218 – 426Fc receptor-like BAdd BLAST409

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi44 ↔ 85PROSITE-ProRule annotation
Disulfide bondi124 ↔ 168PROSITE-ProRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi152N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q6BAA4

PeptideAtlas

More...
PeptideAtlasi
Q6BAA4

PRoteomics IDEntifications database

More...
PRIDEi
Q6BAA4

ProteomicsDB human proteome resource

More...
ProteomicsDBi
66211
66212 [Q6BAA4-2]
66213 [Q6BAA4-3]
66214 [Q6BAA4-4]
66215 [Q6BAA4-5]

Consortium for Top Down Proteomics

More...
TopDownProteomicsi
Q6BAA4-5 [Q6BAA4-5]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q6BAA4

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q6BAA4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed at low levels. Expressed in B-lymphocytes. Detected in tonsil, lung, kidney, spleen and placenta. Expressed by a small subset of germinal center B-cells in tonsils and by melanocytes (at protein level).4 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000162746 Expressed in 111 organ(s), highest expression level in middle temporal gyrus

Genevisible search portal to normalized and curated expression data from Genevestigator

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Genevisiblei
Q6BAA4 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
CAB026139

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000356925

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini23 – 101Ig-like C2-type 1Add BLAST79
Domaini103 – 189Ig-like C2-type 2Add BLAST87

Keywords - Domaini

Immunoglobulin domain, Repeat, Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IDZ6 Eukaryota
ENOG410ZPGM LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00960000186594

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q6BAA4

Identification of Orthologs from Complete Genome Data

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OMAi
LESYWCE

Database of Orthologous Groups

More...
OrthoDBi
866496at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q6BAA4

TreeFam database of animal gene trees

More...
TreeFami
TF351107

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.10, 3 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003599 Ig_sub

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13895 Ig_2, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00409 IG, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48726 SSF48726, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50835 IG_LIKE, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (5)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 5 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Note: Additional isoforms seem to exist.
Isoform 1 (identifier: Q6BAA4-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MWPLTALLLL VPSSGQAATL EKPILSLHPP WTTIFKGERV TLKCDGYHPL
60 70 80 90 100
LLELQPISTL WYLGHLLLPS HKKSIEVQTP GVYRCQTRGA PVSDPIHLSV
110 120 130 140 150
SNDWLILQVP YAPVFEGEPL VLRCRGWYDK VVYKLHYYHD GQAVRYFHSS
160 170 180 190 200
ANYTVLQARA SDSGRYQCSG TMRIPVESAP MFSAKVAVTV QELFRAPVLR
210 220 230 240 250
VMGPREARGA ALGGVVLRCD TRLHPQKRDT PLQFAFYKYS RAVRRFDWGA
260 270 280 290 300
EYTVPEPEVE ELESYWCEAA TATRSVRKRS PWLQLPGPGS PLDPASTTAP
310 320 330 340 350
APWAAALAPG NRPLSFRKPP VSRSVPLVTS VRNTTSTGLQ FPASGAPTAG
360 370 380 390 400
PPACAPPTPL EQSAGALKPD VDLLLREMQL LKGLLSRVVL ELKEPQALRE
410 420
LRGTPETPTS HFAVSPGTPE TTPVES
Length:426
Mass (Da):46,904
Last modified:September 13, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD8AFD136B82D8962
GO
Isoform 2 (identifier: Q6BAA4-2) [UniParc]FASTAAdd to basket
Also known as: FCRL2c1

The sequence of this isoform differs from the canonical sequence as follows:
     193-275: LFRAPVLRVM...WCEAATATRS → ARHAAAVRVL...SSMGRSLGSW
     276-426: Missing.

Show »
Length:275
Mass (Da):30,301
Checksum:i3871C3F3481DF7B0
GO
Isoform 3 (identifier: Q6BAA4-3) [UniParc]FASTAAdd to basket
Also known as: FCRL2c2

The sequence of this isoform differs from the canonical sequence as follows:
     11-17: Missing.
     193-275: LFRAPVLRVM...WCEAATATRS → ARHAAAVRVL...SSMGRSLGSW
     276-426: Missing.

Show »
Length:268
Mass (Da):29,674
Checksum:i0297F0D641FAED60
GO
Isoform 4 (identifier: Q6BAA4-4) [UniParc]FASTAAdd to basket
Also known as: FCRL2b1

The sequence of this isoform differs from the canonical sequence as follows:
     192-318: ELFRAPVLRV...PGNRPLSFRK → AARCAASTGA...RRPWNNRLEP
     319-426: Missing.

Show »
Length:318
Mass (Da):35,250
Checksum:i115A94BA61CF9012
GO
Isoform 5 (identifier: Q6BAA4-5) [UniParc]FASTAAdd to basket
Also known as: FCRL2b2

The sequence of this isoform differs from the canonical sequence as follows:
     11-17: Missing.
     192-318: ELFRAPVLRV...PGNRPLSFRK → AARCAASTGA...RRPWNNRLEP
     319-426: Missing.

Show »
Length:311
Mass (Da):34,623
Checksum:iC6A64A847EBD9008
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti18 – 19AT → VP in AAT77989 (PubMed:15676285).Curated2
Sequence conflicti18 – 19AT → VP in AAT77990 (PubMed:15676285).Curated2

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_03341911 – 17Missing in isoform 3 and isoform 5. 1 Publication7
Alternative sequenceiVSP_033420192 – 318ELFRA…LSFRK → AARCAASTGAPSTQSRSPRS RSSNRTGARRLPPPAVSGNA VRGCSSRGRVLPWTRPPPPP QLHGPQPWLLVIGRFPSESP RCPDRSRWSPPSGTPPPPGC SSRRAAPRLRGHPPALRRRP WNNRLEP in isoform 4 and isoform 5. 1 PublicationAdd BLAST127
Alternative sequenceiVSP_033421193 – 275LFRAP…TATRS → ARHAAAVRVLQVQPRGAPLR LGRRVHSPGARGRGARIVLV RGGYRHPQCPETQSVAAAPG AGFSPGPGLHHRPSSMGRSL GSW in isoform 2 and isoform 3. 1 PublicationAdd BLAST83
Alternative sequenceiVSP_033422276 – 426Missing in isoform 2 and isoform 3. 1 PublicationAdd BLAST151
Alternative sequenceiVSP_033423319 – 426Missing in isoform 4 and isoform 5. 1 PublicationAdd BLAST108

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
DQ021957 mRNA Translation: AAY42534.1
AY786314 mRNA Translation: AAX11390.1
AY670683 mRNA Translation: AAT77987.1
AY670684 mRNA Translation: AAT77988.1
AY670685 mRNA Translation: AAT77989.1
AY670686 mRNA Translation: AAT77990.1
AY670687 mRNA Translation: AAT77991.1
EF064728 Genomic DNA Translation: ABK41911.1
AK290733 mRNA Translation: BAF83422.1
AL359541 Genomic DNA No translation available.
BC038564 mRNA Translation: AAH38564.2

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS30927.1 [Q6BAA4-1]
CCDS72962.1 [Q6BAA4-2]
CCDS72963.1 [Q6BAA4-4]
CCDS72964.1 [Q6BAA4-3]
CCDS72965.1 [Q6BAA4-5]

NCBI Reference Sequences

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RefSeqi
NP_001002901.1, NM_001002901.3 [Q6BAA4-1]
NP_001275758.1, NM_001288829.1 [Q6BAA4-4]
NP_001275759.1, NM_001288830.1 [Q6BAA4-5]
NP_001275760.1, NM_001288831.1 [Q6BAA4-2]
NP_001275761.1, NM_001288832.1 [Q6BAA4-3]
NP_001307170.1, NM_001320241.1 [Q6BAA4-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000336830; ENSP00000338598; ENSG00000162746 [Q6BAA4-2]
ENST00000367944; ENSP00000356921; ENSG00000162746 [Q6BAA4-3]
ENST00000367945; ENSP00000356922; ENSG00000162746 [Q6BAA4-5]
ENST00000367946; ENSP00000356923; ENSG00000162746 [Q6BAA4-4]
ENST00000367948; ENSP00000356925; ENSG00000162746 [Q6BAA4-1]

Database of genes from NCBI RefSeq genomes

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GeneIDi
127943

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:127943

UCSC genome browser

More...
UCSCi
uc001gbh.4 human [Q6BAA4-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ021957 mRNA Translation: AAY42534.1
AY786314 mRNA Translation: AAX11390.1
AY670683 mRNA Translation: AAT77987.1
AY670684 mRNA Translation: AAT77988.1
AY670685 mRNA Translation: AAT77989.1
AY670686 mRNA Translation: AAT77990.1
AY670687 mRNA Translation: AAT77991.1
EF064728 Genomic DNA Translation: ABK41911.1
AK290733 mRNA Translation: BAF83422.1
AL359541 Genomic DNA No translation available.
BC038564 mRNA Translation: AAH38564.2
CCDSiCCDS30927.1 [Q6BAA4-1]
CCDS72962.1 [Q6BAA4-2]
CCDS72963.1 [Q6BAA4-4]
CCDS72964.1 [Q6BAA4-3]
CCDS72965.1 [Q6BAA4-5]
RefSeqiNP_001002901.1, NM_001002901.3 [Q6BAA4-1]
NP_001275758.1, NM_001288829.1 [Q6BAA4-4]
NP_001275759.1, NM_001288830.1 [Q6BAA4-5]
NP_001275760.1, NM_001288831.1 [Q6BAA4-2]
NP_001275761.1, NM_001288832.1 [Q6BAA4-3]
NP_001307170.1, NM_001320241.1 [Q6BAA4-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi9606.ENSP00000356925

PTM databases

iPTMnetiQ6BAA4
PhosphoSitePlusiQ6BAA4

Polymorphism and mutation databases

BioMutaiFCRLB
DMDMi74757430

Proteomic databases

PaxDbiQ6BAA4
PeptideAtlasiQ6BAA4
PRIDEiQ6BAA4
ProteomicsDBi66211
66212 [Q6BAA4-2]
66213 [Q6BAA4-3]
66214 [Q6BAA4-4]
66215 [Q6BAA4-5]
TopDownProteomicsiQ6BAA4-5 [Q6BAA4-5]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000336830; ENSP00000338598; ENSG00000162746 [Q6BAA4-2]
ENST00000367944; ENSP00000356921; ENSG00000162746 [Q6BAA4-3]
ENST00000367945; ENSP00000356922; ENSG00000162746 [Q6BAA4-5]
ENST00000367946; ENSP00000356923; ENSG00000162746 [Q6BAA4-4]
ENST00000367948; ENSP00000356925; ENSG00000162746 [Q6BAA4-1]
GeneIDi127943
KEGGihsa:127943
UCSCiuc001gbh.4 human [Q6BAA4-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
127943
DisGeNETi127943

GeneCards: human genes, protein and diseases

More...
GeneCardsi
FCRLB
HGNCiHGNC:26431 FCRLB
HPAiCAB026139
MIMi609251 gene
neXtProtiNX_Q6BAA4
OpenTargetsiENSG00000162746
PharmGKBiPA162388195

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiENOG410IDZ6 Eukaryota
ENOG410ZPGM LUCA
GeneTreeiENSGT00960000186594
InParanoidiQ6BAA4
OMAiLESYWCE
OrthoDBi866496at2759
PhylomeDBiQ6BAA4
TreeFamiTF351107

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
FCRLB human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
127943

Protein Ontology

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PROi
PR:Q6BAA4

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000162746 Expressed in 111 organ(s), highest expression level in middle temporal gyrus
GenevisibleiQ6BAA4 HS

Family and domain databases

Gene3Di2.60.40.10, 3 hits
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003599 Ig_sub
PfamiView protein in Pfam
PF13895 Ig_2, 2 hits
SMARTiView protein in SMART
SM00409 IG, 2 hits
SUPFAMiSSF48726 SSF48726, 2 hits
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiFCRLB_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6BAA4
Secondary accession number(s): A2A3J5
, A2A3J7, Q5VXA6, Q6BAA0, Q6BAA1, Q6BAA2, Q6BAA3, Q8IXZ7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: September 13, 2004
Last modified: June 5, 2019
This is version 129 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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