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Entry version 134 (07 Oct 2020)
Sequence version 1 (13 Sep 2004)
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Protein

Scavenger receptor class A member 3

Gene

SCARA3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Seems to protect cells by scavenging oxidative molecules or harmful products of oxidation.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • scavenger receptor activity Source: ProtInc

GO - Biological processi

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q6AZY7

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Scavenger receptor class A member 3
Alternative name(s):
Cellular stress response gene protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SCARA3
Synonyms:CSR
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000168077.13

Human Gene Nomenclature Database

More...
HGNCi
HGNC:19000, SCARA3

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
602728, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q6AZY7

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 56CytoplasmicSequence analysisAdd BLAST56
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei57 – 77Helical; Signal-anchor for type II membrane proteinSequence analysisAdd BLAST21
Topological domaini78 – 606ExtracellularSequence analysisAdd BLAST529

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Endoplasmic reticulum, Golgi apparatus, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
51435

Open Targets

More...
OpenTargetsi
ENSG00000168077

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA38775

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q6AZY7, Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
SCARA3

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74736352

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001816331 – 606Scavenger receptor class A member 3Add BLAST606

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi115N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi182N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi224N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi257N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi313N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi337N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi365N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi400N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi430N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi451N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q6AZY7

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q6AZY7

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q6AZY7

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q6AZY7

PeptideAtlas

More...
PeptideAtlasi
Q6AZY7

PRoteomics IDEntifications database

More...
PRIDEi
Q6AZY7

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
66202 [Q6AZY7-1]
66203 [Q6AZY7-2]

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...
GlyGeni
Q6AZY7, 10 sites

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q6AZY7

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q6AZY7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed ubiquitously.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000168077, Expressed in tendon of biceps brachii and 200 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q6AZY7, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000168077, Tissue enhanced (fallopian)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
119539, 52 interactors

Protein interaction database and analysis system

More...
IntActi
Q6AZY7, 29 interactors

Molecular INTeraction database

More...
MINTi
Q6AZY7

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000301904

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q6AZY7, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q6AZY7

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini455 – 513Collagen-like 1Add BLAST59
Domaini544 – 603Collagen-like 2Add BLAST60

Keywords - Domaini

Collagen, Repeat, Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QV37, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000158238

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_027961_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q6AZY7

Identification of Orthologs from Complete Genome Data

More...
OMAi
DQTSQTH

Database of Orthologous Groups

More...
OrthoDBi
508661at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q6AZY7

TreeFam database of animal gene trees

More...
TreeFami
TF332426

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR008160, Collagen

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01391, Collagen, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q6AZY7-1) [UniParc]FASTAAdd to basket
Also known as: CSR1

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MKVRSAGGDG DALCVTEEDL AGDDEDMPTF PCTQKGRPGP RCSRCQKNLS
60 70 80 90 100
LHTSVRILYL FLALLLVAVA VLASLVFRKV DSLSEDISLT QSIYDKKLVL
110 120 130 140 150
MQKNLQGLDP KALNNCSFCH EAGQLGPEIR KLQEELEGIQ KLLLAQEVQL
160 170 180 190 200
DQTLQAQEVL STTSRQISQE MGSCSFSIHQ VNQSLGLFLA QVRGWQATTA
210 220 230 240 250
GLDLSLKDLT QECYDVKAAV HQINFTVGQT SEWIHGIQRK TDEETLTLQK
260 270 280 290 300
IVTDWQNYTR LFSGLRTTST KTGEAVKNIQ ATLGASSQRI SQNSESMHDL
310 320 330 340 350
VLQVMGLQLQ LDNISSFLDD HEENMHDLQY HTHYAQNRTV ERFESLEGRM
360 370 380 390 400
ASHEIEIGTI FTNINATDNH VHSMLKYLDD VRLSCTLGFH THAEELYYLN
410 420 430 440 450
KSVSIMLGTT DLLRERFSLL SARLDLNVRN LSMIVEEMKA VDTQHGEILR
460 470 480 490 500
NVTILRGAPG PPGPRGFKGD MGVKGPVGGR GPKGDPGSLG PLGPQGPQGQ
510 520 530 540 550
PGEAGPVGER GPVGPRGFPG LKGSKGSFGT GGPRGQPGPK GDIGPPGPEG
560 570 580 590 600
PPGSPGPSGP QGKPGIAGKT GSPGQRGAMG PKGEPGIQGP PGLPGPPGPP

GSQSFY
Length:606
Mass (Da):65,137
Last modified:September 13, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i15EEC028AAF7762E
GO
Isoform 2 (identifier: Q6AZY7-2) [UniParc]FASTAAdd to basket
Also known as: CSR2

The sequence of this isoform differs from the canonical sequence as follows:
     458-466: APGPPGPRG → HTLFSHNRI
     467-606: Missing.

Show »
Length:466
Mass (Da):52,434
Checksum:iCE3F14DCBF5CDF31
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti488S → I in BAA86201 (PubMed:9580669).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_025228130R → Q1 PublicationCorresponds to variant dbSNP:rs34791518Ensembl.1
Natural variantiVAR_025229325M → T1 PublicationCorresponds to variant dbSNP:rs33930667Ensembl.1
Natural variantiVAR_025230423R → Q1 PublicationCorresponds to variant dbSNP:rs3735754Ensembl.1
Natural variantiVAR_025231428V → I1 PublicationCorresponds to variant dbSNP:rs34086286Ensembl.1
Natural variantiVAR_025232467F → L1 PublicationCorresponds to variant dbSNP:rs17057523Ensembl.1
Natural variantiVAR_025233551P → S1 PublicationCorresponds to variant dbSNP:rs35928641Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_017135458 – 466APGPPGPRG → HTLFSHNRI in isoform 2. 2 Publications9
Alternative sequenceiVSP_017136467 – 606Missing in isoform 2. 2 PublicationsAdd BLAST140

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB007829 mRNA Translation: BAA86201.1
AB007830 mRNA Translation: BAA86202.1
DQ205185 Genomic DNA Translation: ABA27098.1
BC060811 mRNA Translation: AAH60811.1
BC075067 mRNA Translation: AAH75067.1
BC075068 mRNA Translation: AAH75068.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS34870.1 [Q6AZY7-2]
CCDS34871.1 [Q6AZY7-1]

NCBI Reference Sequences

More...
RefSeqi
NP_057324.2, NM_016240.2 [Q6AZY7-1]
NP_878185.1, NM_182826.1 [Q6AZY7-2]
XP_016869024.1, XM_017013535.1 [Q6AZY7-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000301904; ENSP00000301904; ENSG00000168077 [Q6AZY7-1]
ENST00000337221; ENSP00000337985; ENSG00000168077 [Q6AZY7-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
51435

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:51435

UCSC genome browser

More...
UCSCi
uc003xga.2, human [Q6AZY7-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross%5Freferences%5Fsection">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

NIEHS-SNPs

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB007829 mRNA Translation: BAA86201.1
AB007830 mRNA Translation: BAA86202.1
DQ205185 Genomic DNA Translation: ABA27098.1
BC060811 mRNA Translation: AAH60811.1
BC075067 mRNA Translation: AAH75067.1
BC075068 mRNA Translation: AAH75068.1
CCDSiCCDS34870.1 [Q6AZY7-2]
CCDS34871.1 [Q6AZY7-1]
RefSeqiNP_057324.2, NM_016240.2 [Q6AZY7-1]
NP_878185.1, NM_182826.1 [Q6AZY7-2]
XP_016869024.1, XM_017013535.1 [Q6AZY7-1]

3D structure databases

SMRiQ6AZY7
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi119539, 52 interactors
IntActiQ6AZY7, 29 interactors
MINTiQ6AZY7
STRINGi9606.ENSP00000301904

PTM databases

GlyGeniQ6AZY7, 10 sites
iPTMnetiQ6AZY7
PhosphoSitePlusiQ6AZY7

Polymorphism and mutation databases

BioMutaiSCARA3
DMDMi74736352

Proteomic databases

jPOSTiQ6AZY7
MassIVEiQ6AZY7
MaxQBiQ6AZY7
PaxDbiQ6AZY7
PeptideAtlasiQ6AZY7
PRIDEiQ6AZY7
ProteomicsDBi66202 [Q6AZY7-1]
66203 [Q6AZY7-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
23041, 114 antibodies

The DNASU plasmid repository

More...
DNASUi
51435

Genome annotation databases

EnsembliENST00000301904; ENSP00000301904; ENSG00000168077 [Q6AZY7-1]
ENST00000337221; ENSP00000337985; ENSG00000168077 [Q6AZY7-2]
GeneIDi51435
KEGGihsa:51435
UCSCiuc003xga.2, human [Q6AZY7-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
51435
DisGeNETi51435
EuPathDBiHostDB:ENSG00000168077.13

GeneCards: human genes, protein and diseases

More...
GeneCardsi
SCARA3
HGNCiHGNC:19000, SCARA3
HPAiENSG00000168077, Tissue enhanced (fallopian)
MIMi602728, gene
neXtProtiNX_Q6AZY7
OpenTargetsiENSG00000168077
PharmGKBiPA38775

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG502QV37, Eukaryota
GeneTreeiENSGT00940000158238
HOGENOMiCLU_027961_0_0_1
InParanoidiQ6AZY7
OMAiDQTSQTH
OrthoDBi508661at2759
PhylomeDBiQ6AZY7
TreeFamiTF332426

Enzyme and pathway databases

PathwayCommonsiQ6AZY7

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
51435, 2 hits in 870 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
SCARA3, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
51435
PharosiQ6AZY7, Tbio

Protein Ontology

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PROi
PR:Q6AZY7
RNActiQ6AZY7, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000168077, Expressed in tendon of biceps brachii and 200 other tissues
GenevisibleiQ6AZY7, HS

Family and domain databases

InterProiView protein in InterPro
IPR008160, Collagen
PfamiView protein in Pfam
PF01391, Collagen, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSCAR3_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6AZY7
Secondary accession number(s): Q9UM15, Q9UM16
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 7, 2006
Last sequence update: September 13, 2004
Last modified: October 7, 2020
This is version 134 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. Human chromosome 8
    Human chromosome 8: entries, gene names and cross-references to MIM
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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