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Entry version 102 (12 Aug 2020)
Sequence version 1 (13 Sep 2004)
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Protein

Zinc finger MYND domain-containing protein 10

Gene

Zmynd10

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Plays a role in axonemal structure organization and motility. Involved in axonemal pre-assembly of inner and outer dynein arms (IDA and ODA, respectively) for proper axoneme building for cilia motility (By similarity). May act by indirectly regulating transcription of dynein proteins (By similarity).By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri394 – 430MYND-typePROSITE-ProRule annotationAdd BLAST37

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger MYND domain-containing protein 10
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Zmynd10
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRattus norvegicus (Rat)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10116 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002494 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8
  • UP000234681 Componentsi: Chromosome 8, Unassembled WGS sequence

Organism-specific databases

Rat genome database

More...
RGDi
1303250, Zmynd10

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell membrane, Cytoplasm, Cytoskeleton, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004248151 – 440Zinc finger MYND domain-containing protein 10Add BLAST440

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q6AXZ5

PRoteomics IDEntifications database

More...
PRIDEi
Q6AXZ5

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q6AXZ5

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q6AXZ5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSRNOG00000021602, Expressed in testis and 21 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q6AXZ5, RN

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts (via C-terminus) with LRRC6 (via CS domain); this interaction stabilizes LRRC6 at the protein level.

Interacts (via C-terminus) with DNAL1; this interaction stabilizes DNAL1 at the protein level.

Interacts with DNAAF4, HSPA8, IQUB, RUVBL2 and TCTEX1D1.

By similarity

Protein-protein interaction databases

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q6AXZ5

STRING: functional protein association networks

More...
STRINGi
10116.ENSRNOP00000031055

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q6AXZ5

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the ZMYND10 family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri394 – 430MYND-typePROSITE-ProRule annotationAdd BLAST37

Keywords - Domaini

Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QS3F, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153820

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_034036_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q6AXZ5

KEGG Orthology (KO)

More...
KOi
K24030

Identification of Orthologs from Complete Genome Data

More...
OMAi
IYTVLYH

Database of Orthologous Groups

More...
OrthoDBi
685805at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q6AXZ5

TreeFam database of animal gene trees

More...
TreeFami
TF324215

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR017333, UCP037948_Znf-MYND
IPR002893, Znf_MYND

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01753, zf-MYND, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF037948, UCP037948_Znf_MYND10, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01360, ZF_MYND_1, 1 hit
PS50865, ZF_MYND_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q6AXZ5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGDLELLLPG EAEVLVQGLH SFQLREMGSE GWSKQHENLE KLNMQAILDA
60 70 80 90 100
TVSQAEPIQE LLVTHGKIPT LVEELIAVEM WKQKVFPVLC RLEDFKPQNT
110 120 130 140 150
FPIYMVVHHE ASIINLLETV FFHKEVCESA DDTVLDLVDY CHRKLILLVA
160 170 180 190 200
RKGGGDLSEE ERFQDSTPMQ ELQKQAEMME FEISLKALSV LRYITDCMDS
210 220 230 240 250
LSLSTLNRML TTHNLPCLLV ELLEHSPWSR REGGKLQHFE SGRWQTVAPS
260 270 280 290 300
EHQKLNKLDG QVWIALYNLL LSPEARTRYC LTNFAKGQLL KLQAFLTDTL
310 320 330 340 350
LDQLPNLADL KSFLAHLALV ETQPPKKDLV LEQIPEIWDR LERENKGKWQ
360 370 380 390 400
AIAKHQLQHV FSLSEKDLRQ QAQRWAETYR LDVLEAVAPE RPRCAYCSAE
410 420 430 440
ASKRCSRCQK VWYCCRECQV KHWEKHGKTC VLAAQGDRAK
Length:440
Mass (Da):50,675
Last modified:September 13, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i824114B160977B47
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AABR06057029 Genomic DNA No translation available.
CH473954 Genomic DNA Translation: EDL77250.1
BC079255 mRNA Translation: AAH79255.1

NCBI Reference Sequences

More...
RefSeqi
NP_001004284.1, NM_001004284.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSRNOT00000039258; ENSRNOP00000031055; ENSRNOG00000021602

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
363139

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
rno:363139

UCSC genome browser

More...
UCSCi
RGD:1303250, rat

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR06057029 Genomic DNA No translation available.
CH473954 Genomic DNA Translation: EDL77250.1
BC079255 mRNA Translation: AAH79255.1
RefSeqiNP_001004284.1, NM_001004284.1

3D structure databases

SMRiQ6AXZ5
ModBaseiSearch...

Protein-protein interaction databases

CORUMiQ6AXZ5
STRINGi10116.ENSRNOP00000031055

PTM databases

iPTMnetiQ6AXZ5
PhosphoSitePlusiQ6AXZ5

Proteomic databases

PaxDbiQ6AXZ5
PRIDEiQ6AXZ5

Genome annotation databases

EnsembliENSRNOT00000039258; ENSRNOP00000031055; ENSRNOG00000021602
GeneIDi363139
KEGGirno:363139
UCSCiRGD:1303250, rat

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
51364
RGDi1303250, Zmynd10

Phylogenomic databases

eggNOGiENOG502QS3F, Eukaryota
GeneTreeiENSGT00940000153820
HOGENOMiCLU_034036_1_0_1
InParanoidiQ6AXZ5
KOiK24030
OMAiIYTVLYH
OrthoDBi685805at2759
PhylomeDBiQ6AXZ5
TreeFamiTF324215

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q6AXZ5

Gene expression databases

BgeeiENSRNOG00000021602, Expressed in testis and 21 other tissues
GenevisibleiQ6AXZ5, RN

Family and domain databases

InterProiView protein in InterPro
IPR017333, UCP037948_Znf-MYND
IPR002893, Znf_MYND
PfamiView protein in Pfam
PF01753, zf-MYND, 1 hit
PIRSFiPIRSF037948, UCP037948_Znf_MYND10, 1 hit
PROSITEiView protein in PROSITE
PS01360, ZF_MYND_1, 1 hit
PS50865, ZF_MYND_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZMY10_RAT
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6AXZ5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 11, 2013
Last sequence update: September 13, 2004
Last modified: August 12, 2020
This is version 102 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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