Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Meiosis-specific nuclear structural protein 1

Gene

Mns1

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May play a role in the control of meiotic division and germ cell differentiation through regulation of pairing and recombination during meiosis.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processMeiosis

Names & Taxonomyi

Protein namesi
Recommended name:
Meiosis-specific nuclear structural protein 1
Gene namesi
Name:Mns1
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 8

Organism-specific databases

RGDi1549718 Mns1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002989241 – 498Meiosis-specific nuclear structural protein 1Add BLAST498

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei188PhosphotyrosineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ6AXQ8
PRIDEiQ6AXQ8

PTM databases

PhosphoSitePlusiQ6AXQ8

Expressioni

Gene expression databases

BgeeiENSRNOG00000057867 Expressed in 9 organ(s), highest expression level in testis
GenevisibleiQ6AXQ8 RN

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

BioGridi263961, 1 interactor
STRINGi10116.ENSRNOP00000007941

Structurei

3D structure databases

ProteinModelPortaliQ6AXQ8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili29 – 253Sequence analysisAdd BLAST225
Coiled coili287 – 360Sequence analysisAdd BLAST74
Coiled coili390 – 437Sequence analysisAdd BLAST48

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi46 – 447Glu-richAdd BLAST402

Sequence similaritiesi

Belongs to the MNS1 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410IFU7 Eukaryota
ENOG410YXPQ LUCA
GeneTreeiENSGT00730000111210
HOGENOMiHOG000006500
HOVERGENiHBG108140
InParanoidiQ6AXQ8
OMAiNAQKQRM
OrthoDBiEOG091G0CNW
PhylomeDBiQ6AXQ8
TreeFamiTF329219

Family and domain databases

InterProiView protein in InterPro
IPR026504 MNS1
PANTHERiPTHR19265 PTHR19265, 1 hit

Sequencei

Sequence statusi: Complete.

Q6AXQ8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MANKKRAMSF SEKHQQLVDE NFRKSLHVQV LNKLERQAKN QVVQNENDER
60 70 80 90 100
VERQRFLRVL QNEQFELDME EAVQKAEENK RMRDRQLEQE ERLANELARL
110 120 130 140 150
KHESLKDEKM RQQVRENSIE LRELEQKLKA AYMNKERAAQ IVEKDVIKYE
160 170 180 190 200
QMKRDAEIER IMMEEHKRLL KEENVKQEKR DKERAQYYVD LEKQLEDQER
210 220 230 240 250
RKQEAYEQLL KEKLMIDEIV RKIYEEDQLE RQQKLEKRNA IQKYIKEFQR
260 270 280 290 300
AQDLWRQKKR EEMEEENRKI LEFAKIQEQR EGERMARVQE SEEKRVQRQN
310 320 330 340 350
LLIQKLEETL RQRDDLERVR QELYLEEYAE FIKLKMKEEV EQRLRKQRDR
360 370 380 390 400
KQDFKDQMAL REVLLQAAKE EEEAFKKAML AKFAEDDRIE LMNAQKQRMK
410 420 430 440 450
QLEHKRAVEK LIEERRNQFL ADKQRELEEL QLQQRRQGCI NEIIEEERLR
460 470 480 490
LLKEHASKLL GYLPKGVFKK EDDVDMLGEE FRKAYQKKSE VCEEKGSS
Length:498
Mass (Da):61,240
Last modified:September 13, 2004 - v1
Checksum:i5E6611EF664B51B1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC079390 mRNA Translation: AAH79390.1
RefSeqiNP_001007753.1, NM_001007752.1
UniGeneiRn.19338

Genome annotation databases

EnsembliENSRNOT00000077613; ENSRNOP00000069371; ENSRNOG00000057867
GeneIDi363093
KEGGirno:363093
UCSCiRGD:1549718 rat

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC079390 mRNA Translation: AAH79390.1
RefSeqiNP_001007753.1, NM_001007752.1
UniGeneiRn.19338

3D structure databases

ProteinModelPortaliQ6AXQ8
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi263961, 1 interactor
STRINGi10116.ENSRNOP00000007941

PTM databases

PhosphoSitePlusiQ6AXQ8

Proteomic databases

PaxDbiQ6AXQ8
PRIDEiQ6AXQ8

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000077613; ENSRNOP00000069371; ENSRNOG00000057867
GeneIDi363093
KEGGirno:363093
UCSCiRGD:1549718 rat

Organism-specific databases

CTDi55329
RGDi1549718 Mns1

Phylogenomic databases

eggNOGiENOG410IFU7 Eukaryota
ENOG410YXPQ LUCA
GeneTreeiENSGT00730000111210
HOGENOMiHOG000006500
HOVERGENiHBG108140
InParanoidiQ6AXQ8
OMAiNAQKQRM
OrthoDBiEOG091G0CNW
PhylomeDBiQ6AXQ8
TreeFamiTF329219

Miscellaneous databases

PROiPR:Q6AXQ8

Gene expression databases

BgeeiENSRNOG00000057867 Expressed in 9 organ(s), highest expression level in testis
GenevisibleiQ6AXQ8 RN

Family and domain databases

InterProiView protein in InterPro
IPR026504 MNS1
PANTHERiPTHR19265 PTHR19265, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiMNS1_RAT
AccessioniPrimary (citable) accession number: Q6AXQ8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 21, 2007
Last sequence update: September 13, 2004
Last modified: November 7, 2018
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again