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Protein

Guanylate kinase

Gene

gmk

Organism
Leifsonia xyli subsp. xyli (strain CTCB07)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential for recycling GMP and indirectly, cGMP.UniRule annotation

Catalytic activityi

ATP + GMP = ADP + GDP.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi71 – 78ATPUniRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Transferase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Guanylate kinaseUniRule annotation (EC:2.7.4.8UniRule annotation)
Alternative name(s):
GMP kinaseUniRule annotation
Gene namesi
Name:gmkUniRule annotation
Ordered Locus Names:Lxx11120
OrganismiLeifsonia xyli subsp. xyli (strain CTCB07)
Taxonomic identifieri281090 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaMicrococcalesMicrobacteriaceaeLeifsonia
Proteomesi
  • UP000001306 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002663431 – 254Guanylate kinaseAdd BLAST254

Interactioni

Protein-protein interaction databases

STRINGi281090.Lxx11120

Structurei

3D structure databases

ProteinModelPortaliQ6AF82
SMRiQ6AF82
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini64 – 243Guanylate kinase-likeUniRule annotationAdd BLAST180

Sequence similaritiesi

Belongs to the guanylate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108UHA Bacteria
COG0194 LUCA
HOGENOMiHOG000037640
KOiK00942
OMAiWATVHNA
OrthoDBiPOG091H01Q4

Family and domain databases

HAMAPiMF_00328 Guanylate_kinase, 1 hit
InterProiView protein in InterPro
IPR008145 GK/Ca_channel_bsu
IPR008144 Guanylate_kin-like_dom
IPR017665 Guanylate_kinase
IPR020590 Guanylate_kinase_CS
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00625 Guanylate_kin, 1 hit
SMARTiView protein in SMART
SM00072 GuKc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR03263 guanyl_kin, 1 hit
PROSITEiView protein in PROSITE
PS00856 GUANYLATE_KINASE_1, 1 hit
PS50052 GUANYLATE_KINASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q6AF82-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEGRIRVTEF LLSVPAIGTT KTQDALRRLG IAPSKRLGGL GRHQRLRLRV
60 70 80 90 100
FLIEREERPV RRRKHLVVLA GPTAVGKGTV SAYIRENYPE VLLSVSATTR
110 120 130 140 150
SPRPGEVDGV NYYFVDDAAF DRMIAAGDLL EHATVHNAYR YGTPRAPIEK
160 170 180 190 200
ALDDGRSVLL EIDLQGARQV RASMPEARLI FLLPPTWEEL VRRLTGRGTE
210 220 230 240 250
DAAEQQRRLE TAKVELAAQN EFDHRVVNHT VADAAREVVD LMMVRPAPVR

PSTA
Length:254
Mass (Da):28,385
Last modified:September 13, 2004 - v1
Checksum:iDA832AE93BF3F6C1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016822 Genomic DNA Translation: AAT88963.1

Genome annotation databases

EnsemblBacteriaiAAT88963; AAT88963; Lxx11120
KEGGilxx:Lxx11120

Similar proteinsi

Entry informationi

Entry nameiKGUA_LEIXX
AccessioniPrimary (citable) accession number: Q6AF82
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: September 13, 2004
Last modified: June 7, 2017
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome