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UniProtKB - Q6A085 (ZN629_MOUSE)
Protein
Zinc finger protein 629
Gene
Znf629
Organism
Mus musculus (Mouse)
Status
Functioni
May be involved in transcriptional regulation.
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 149 – 171 | C2H2-type 1PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 177 – 199 | C2H2-type 2PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 205 – 227 | C2H2-type 3PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 233 – 255 | C2H2-type 4PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 261 – 283 | C2H2-type 5PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 289 – 311 | C2H2-type 6PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 317 – 339 | C2H2-type 7PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 345 – 367 | C2H2-type 8PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 373 – 395 | C2H2-type 9PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 401 – 423 | C2H2-type 10PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 429 – 451 | C2H2-type 11PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 457 – 479 | C2H2-type 12PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 485 – 507 | C2H2-type 13PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 513 – 535 | C2H2-type 14PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 568 – 590 | C2H2-type 15PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 661 – 683 | C2H2-type 16PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 713 – 735 | C2H2-type 17PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 766 – 788 | C2H2-type 18PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 840 – 862 | C2H2-type 19PROSITE-ProRule annotationAdd BLAST | 23 |
GO - Molecular functioni
- DNA-binding transcription activator activity, RNA polymerase II-specific Source: GO_Central
- metal ion binding Source: UniProtKB-KW
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: GO_Central
GO - Biological processi
- regulation of transcription by RNA polymerase II Source: GO_Central
Keywordsi
Molecular function | DNA-binding |
Biological process | Transcription, Transcription regulation |
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Recommended name: Zinc finger protein 629 |
Gene namesi | Name:Znf629 Synonyms:Kiaa0326, Zfp629 |
Organismi | Mus musculus (Mouse) |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:2444524, Zfp629 |
VEuPathDBi | HostDB:ENSMUSG00000045639 |
Subcellular locationi
Nucleus
- Nucleus Curated
Nucleus
- nucleus Source: GO_Central
Keywords - Cellular componenti
NucleusPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000280427 | 1 – 867 | Zinc finger protein 629Add BLAST | 867 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 18 | PhosphoserineBy similarity | 1 | |
Cross-linki | 250 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity | ||
Cross-linki | 687 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity | ||
Cross-linki | 748 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity | ||
Cross-linki | 838 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity |
Keywords - PTMi
Isopeptide bond, Phosphoprotein, Ubl conjugationProteomic databases
EPDi | Q6A085 |
MaxQBi | Q6A085 |
PaxDbi | Q6A085 |
PeptideAtlasi | Q6A085 |
PRIDEi | Q6A085 |
ProteomicsDBi | 275021 |
PTM databases
iPTMneti | Q6A085 |
PhosphoSitePlusi | Q6A085 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000045639, Expressed in dorsal pancreas and 268 other tissues |
Genevisiblei | Q6A085, MM |
Interactioni
Protein-protein interaction databases
STRINGi | 10090.ENSMUSP00000053760 |
Miscellaneous databases
RNActi | Q6A085, protein |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 104 | DisorderedSequence analysisAdd BLAST | 104 | |
Regioni | 596 – 656 | DisorderedSequence analysisAdd BLAST | 61 | |
Regioni | 786 – 839 | DisorderedSequence analysisAdd BLAST | 54 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 61 – 89 | Polar residuesSequence analysisAdd BLAST | 29 | |
Compositional biasi | 798 – 824 | Polar residuesSequence analysisAdd BLAST | 27 |
Sequence similaritiesi
Belongs to the krueppel C2H2-type zinc-finger protein family.Curated
Zinc finger
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 149 – 171 | C2H2-type 1PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 177 – 199 | C2H2-type 2PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 205 – 227 | C2H2-type 3PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 233 – 255 | C2H2-type 4PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 261 – 283 | C2H2-type 5PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 289 – 311 | C2H2-type 6PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 317 – 339 | C2H2-type 7PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 345 – 367 | C2H2-type 8PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 373 – 395 | C2H2-type 9PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 401 – 423 | C2H2-type 10PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 429 – 451 | C2H2-type 11PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 457 – 479 | C2H2-type 12PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 485 – 507 | C2H2-type 13PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 513 – 535 | C2H2-type 14PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 568 – 590 | C2H2-type 15PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 661 – 683 | C2H2-type 16PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 713 – 735 | C2H2-type 17PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 766 – 788 | C2H2-type 18PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 840 – 862 | C2H2-type 19PROSITE-ProRule annotationAdd BLAST | 23 |
Keywords - Domaini
Repeat, Zinc-fingerPhylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000161909 |
HOGENOMi | CLU_014070_0_0_1 |
InParanoidi | Q6A085 |
OMAi | FKMPEGQ |
OrthoDBi | 1318335at2759 |
PhylomeDBi | Q6A085 |
TreeFami | TF350847 |
Family and domain databases
InterProi | View protein in InterPro IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF00096, zf-C2H2, 14 hits |
SMARTi | View protein in SMART SM00355, ZnF_C2H2, 19 hits |
SUPFAMi | SSF57667, SSF57667, 12 hits |
PROSITEi | View protein in PROSITE PS00028, ZINC_FINGER_C2H2_1, 19 hits PS50157, ZINC_FINGER_C2H2_2, 19 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All
Q6A085-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MEPETVLWGP DLQGPEESQN EAHRGAGSGN EEESPQQESS GEEIILGDPA
60 70 80 90 100
QSPESKDPSE MPLESPSQDA SAPQDSPTPL GSSPLDHQTP MDPSAPEVVP
110 120 130 140 150
SPSEWTKACE TNWQWGTLTP WNSTPVVTAS EPSLRELVQG RPSGAEKPYI
160 170 180 190 200
CNECGKSFSQ WSKLLRHQRI HTGERPNTCS ECGKSFTQSS HLVQHQRTHT
210 220 230 240 250
GEKPYKCPDC GKCFSWSSNL VQHQRTHTGE KPYKCTECEK AFTQSTNLIK
260 270 280 290 300
HQRSHTGEKP YKCGECRRAF YRSSDLIQHQ ATHTGEKPYK CPECGKRFGQ
310 320 330 340 350
NHNLLKHQKI HAGEKPYRCT ECGKSFIQSS ELTQHQRTHT GEKPYECLEC
360 370 380 390 400
GKSFGHSSTL IKHQRTHLRE DPFKCPVCGK TFTLSATLLR HQRTHTGERP
410 420 430 440 450
YKCPECGKSF SVSSNLINHQ RIHRGERPYI CADCGKSFIM SSTLIRHQRI
460 470 480 490 500
HTGEKPYKCS DCGKSFIRSS HLIQHRRTHT GEKPYKCPEC GKSFSQSSNL
510 520 530 540 550
ITHVRTHMDE NLFVCSDCGK AFLEAQELEQ HRVIHERGKT PARRAQGDSL
560 570 580 590 600
LGFGDPALMT PPPGAKPHKC LVCGKGFNDE GIFMQHQRIH IGENPYKNAD
610 620 630 640 650
GLITHPAPKP QQLRPSRLPF GGNSHPGASE SRADPPGQPS KVPESQEGSG
660 670 680 690 700
QRPGQPSPKC YVCSHCGESF LDRAVLLQHQ LTHGNEKPFL FPECRTGRGE
710 720 730 740 750
GAGPSPFLNA KPFKCPECKK SFGLSSELLQ HQKVHAGGKS QKSSELGKSS
760 770 780 790 800
SVLLEHLRSP LGARPYSCSD CGASFLDRLA LTRHQETHTH ERASTPEDTP
810 820 830 840 850
SESATLSTNQ EDEGEASTPP KSSSHGEEES PKTVSEKKPF LCPECGDGFT
860
EVATLLLHRS CHPGVSL
Computationally mapped potential isoform sequencesi
There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketD3Z5P9 | D3Z5P9_MOUSE | Zinc finger protein 629 | Zfp629 | 244 | Annotation score: | ||
D3YV15 | D3YV15_MOUSE | Zinc finger protein 629 | Zfp629 | 195 | Annotation score: | ||
A0A087WR77 | A0A087WR77_MOUSE | Zinc finger protein 629 | Zfp629 | 115 | Annotation score: | ||
A0A087WSE9 | A0A087WSE9_MOUSE | Zinc finger protein 629 | Zfp629 | 47 | Annotation score: |
Sequence cautioni
The sequence BAD32211 differs from that shown. Reason: Erroneous initiation.Curated
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 319 | C → Y in BAC27286 (PubMed:16141072).Curated | 1 | |
Sequence conflicti | 385 | S → R in BAC27286 (PubMed:16141072).Curated | 1 | |
Sequence conflicti | 545 | A → D in BAC27286 (PubMed:16141072).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK172933 mRNA Translation: BAD32211.1 Different initiation. AK031161 mRNA Translation: BAC27286.1 AK034484 mRNA Translation: BAC28725.1 BC035547 mRNA Translation: AAH35547.1 BC067053 mRNA Translation: AAH67053.1 |
CCDSi | CCDS21873.1 |
RefSeqi | NP_796200.1, NM_177226.5 XP_006508016.1, XM_006507953.3 XP_011240135.1, XM_011241833.2 |
Genome annotation databases
Ensembli | ENSMUST00000058038; ENSMUSP00000053760; ENSMUSG00000045639 ENSMUST00000084564; ENSMUSP00000081612; ENSMUSG00000045639 ENSMUST00000122066; ENSMUSP00000113903; ENSMUSG00000045639 |
GeneIDi | 320683 |
KEGGi | mmu:320683 |
UCSCi | uc009jwh.1, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK172933 mRNA Translation: BAD32211.1 Different initiation. AK031161 mRNA Translation: BAC27286.1 AK034484 mRNA Translation: BAC28725.1 BC035547 mRNA Translation: AAH35547.1 BC067053 mRNA Translation: AAH67053.1 |
CCDSi | CCDS21873.1 |
RefSeqi | NP_796200.1, NM_177226.5 XP_006508016.1, XM_006507953.3 XP_011240135.1, XM_011241833.2 |
3D structure databases
AlphaFoldDBi | Q6A085 |
SMRi | Q6A085 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 10090.ENSMUSP00000053760 |
PTM databases
iPTMneti | Q6A085 |
PhosphoSitePlusi | Q6A085 |
Proteomic databases
EPDi | Q6A085 |
MaxQBi | Q6A085 |
PaxDbi | Q6A085 |
PeptideAtlasi | Q6A085 |
PRIDEi | Q6A085 |
ProteomicsDBi | 275021 |
Protocols and materials databases
Antibodypediai | 7095, 12 antibodies from 7 providers |
DNASUi | 320683 |
Genome annotation databases
Ensembli | ENSMUST00000058038; ENSMUSP00000053760; ENSMUSG00000045639 ENSMUST00000084564; ENSMUSP00000081612; ENSMUSG00000045639 ENSMUST00000122066; ENSMUSP00000113903; ENSMUSG00000045639 |
GeneIDi | 320683 |
KEGGi | mmu:320683 |
UCSCi | uc009jwh.1, mouse |
Organism-specific databases
CTDi | 320683 |
MGIi | MGI:2444524, Zfp629 |
VEuPathDBi | HostDB:ENSMUSG00000045639 |
Rougei | Search... |
Phylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000161909 |
HOGENOMi | CLU_014070_0_0_1 |
InParanoidi | Q6A085 |
OMAi | FKMPEGQ |
OrthoDBi | 1318335at2759 |
PhylomeDBi | Q6A085 |
TreeFami | TF350847 |
Miscellaneous databases
BioGRID-ORCSi | 320683, 1 hit in 72 CRISPR screens |
ChiTaRSi | Zfp629, mouse |
PROi | PR:Q6A085 |
RNActi | Q6A085, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000045639, Expressed in dorsal pancreas and 268 other tissues |
Genevisiblei | Q6A085, MM |
Family and domain databases
InterProi | View protein in InterPro IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF00096, zf-C2H2, 14 hits |
SMARTi | View protein in SMART SM00355, ZnF_C2H2, 19 hits |
SUPFAMi | SSF57667, SSF57667, 12 hits |
PROSITEi | View protein in PROSITE PS00028, ZINC_FINGER_C2H2_1, 19 hits PS50157, ZINC_FINGER_C2H2_2, 19 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | ZN629_MOUSE | |
Accessioni | Q6A085Primary (citable) accession number: Q6A085 Secondary accession number(s): Q8BG88, Q8BIR0 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | March 20, 2007 |
Last sequence update: | March 20, 2007 | |
Last modified: | May 25, 2022 | |
This is version 137 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot - SIMILARITY comments
Index of protein domains and families