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UniProtKB - Q6A060 (Q6A060_MOUSE)

Entry version 86 (07 Apr 2021)
Sequence version 1 (13 Sep 2004)
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Protein
Submitted name:

MKIAA0482 protein

Gene

Per1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processBiological rhythmsARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
MKIAA0482 proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Per1Imported
Synonyms:mKIAA0482Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...MGIi		MGI:1098283, Per1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

CytoplasmARBA annotation

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q6A060, MM

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini413 – 456PASInterPro annotationAdd BLAST44

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 174DisorderedSequence analysisAdd BLAST174
Regioni548 – 584DisorderedSequence analysisAdd BLAST37
Regioni687 – 738DisorderedSequence analysisAdd BLAST52
Regioni789 – 812DisorderedSequence analysisAdd BLAST24
Regioni849 – 913DisorderedSequence analysisAdd BLAST65
Regioni978 – 1077DisorderedSequence analysisAdd BLAST100
Regioni1091 – 1139DisorderedSequence analysisAdd BLAST49
Regioni1247 – 1331DisorderedSequence analysisAdd BLAST85

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi59 – 75Pro-richSequence analysisAdd BLAST17
Compositional biasi83 – 174PolarSequence analysisAdd BLAST92
Compositional biasi687 – 705PolarSequence analysisAdd BLAST19
Compositional biasi791 – 809Pro-richSequence analysisAdd BLAST19
Compositional biasi864 – 885BasicSequence analysisAdd BLAST22
Compositional biasi893 – 913Pro-richSequence analysisAdd BLAST21
Compositional biasi986 – 1008Pro-richSequence analysisAdd BLAST23
Compositional biasi1012 – 1029PolarSequence analysisAdd BLAST18
Compositional biasi1296 – 1314PolarSequence analysisAdd BLAST19

Family and domain databases

Conserved Domains Database

More...CDDi		cd00130, PAS, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR000014, PAS
IPR035965, PAS-like_dom_sf
IPR013655, PAS_fold_3
IPR022728, Period_circadian-like_C

Pfam protein domain database

More...Pfami		View protein in Pfam
PF08447, PAS_3, 1 hit
PF12114, Period_C, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00091, PAS, 2 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF55785, SSF55785, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50112, PAS, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

Q6A060-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
ISQPSETGVL PPLSRPQKPR CAPVVASSPS LFRPPLYGPD MSGPLEGADG 
        60         70         80         90        100
GGDPRPGEPF CPGGVPSPGA PQHRPCPGPS LADDTDANSN GSSGNESNGP 
       110        120        130        140        150
ESRGASQRSS HSSSSGNGKD SALLETTESS KSTNSQSPSP PSSSIAYSLL 
       160        170        180        190        200
SASSEQDNPS TSGCSSEQSA RARTQKELMT ALRELKLRLP PERRGKGRSG 
       210        220        230        240        250
TLATLQYALA CVKQVQANQE YYQQWSLEEG EPCAMDMSTY TLEELEHITS 
       260        270        280        290        300
EYTLRNQDTF SVAVSFLTGR IVYISEQAGV LLRCKRDVFR GARFSELLAP 
       310        320        330        340        350
QDVGVFYGST TPSRLPTWGT GTSAGSGLKD FTQEKSVFCR IRGGPDRDPG 
       360        370        380        390        400
PRYQPFRLTP YVTKIRVSDG APAQPCCLLI AERIHSGYEA PRIPPDKRIF 
       410        420        430        440        450
TTRHTPSCLF QDVDERAAPL LGYLPQDLLG APVLLFLHPE DRPLMLAIHK 
       460        470        480        490        500
KILQLAGQPF DHSPIRFCAR NGEYVTMDTS WAGFVHPWSR KVAFVLGRHK 
       510        520        530        540        550
VRTAPLNEDV STPPAPSPAP SLDSDIQELS EQIHRLLLQP VHSSSPTGLC 
       560        570        580        590        600
GVGPLMSPGP LHSPGSSSDS NGGDAEGPGP PAPVTFQQIC KDVHLVKHQG 
       610        620        630        640        650
QQLFIESRAK PPPRPRLLAT GTFKAKVLPC QSPNPELEVA PVPDQASLAL 
       660        670        680        690        700
APEEPERKET SGCSYQQINC LDSILRYLES CNIPSTTKRK CASSSSYTAS 
       710        720        730        740        750
SASDDDKQRA GPVPVGAKKD PSSAMLSGEG ATPRKEPVVG GTLSPLALAN 
       760        770        780        790        800
KAESVVSVTS QCSFSSTIVH VGDKKPPESD IIMMEDLPGL APGPAPSPAP 
       810        820        830        840        850
SPTVAPDPTP DAYRPVGLTK AVLSLHTQKE EQAFLNRFRD LGRLRGLDTS 
       860        870        880        890        900
SVAPSAPGCH HGPIPPGRRH HCRSKAKRSR HHHHQTPRPE TPCYVSHPSP 
       910        920        930        940        950
VPSSGPWPPP PATTPFPAMV QPYPLPVFSP RGGPQPLPPA PTSVSPATFP 
       960        970        980        990       1000
SPLVTPMVAL VLPNYLFPTP PSYPYGVSQA PVEGPPTPAS HSPSPSLPPP 
      1010       1020       1030       1040       1050
PLSPPHRPDS PLFNSRCSSP LQLNLLQLEE SPRTEGGAAA GGPGSSAGPL 
      1060       1070       1080       1090       1100
PPSEETAEPE ARLVEVTESS NQDALSGSSD LLELLLQEDS RSGTGSAASG 
      1110       1120       1130       1140       1150
SLGSGLGSGS GSGSHEGGST SASITRSSQS SHTSKYFGSI DSSEAEAGAA 
      1160       1170       1180       1190       1200
RARTEPGDQV IKCVLQDPIW LLMANADQRV MMTYQVPSRD AASVLKQDRE 
      1210       1220       1230       1240       1250
RLRAMQKQQP RFSEDQRREL GAVHSWVRKG QLPRALDVTA CVDCGSSVQD 
      1260       1270       1280       1290       1300
PGHSDDPLFS ELDGLGLEPM EEGGGEGGGC GVGGGGGDGG EEAQTQIGAK 
      1310       1320       1330 
GSSSQDSAME EEEQGGGSSS PALPAEENST S
Length:1,331
Mass (Da):140,538
Last modified:September 13, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i668F5EEB8EC33C86
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AK172958 mRNA Translation: BAD32236.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK172958 mRNA Translation: BAD32236.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Organism-specific databases

MGIiMGI:1098283, Per1

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		18626, 1 hit in 52 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		Per1, mouse

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

GenevisibleiQ6A060, MM

Family and domain databases

CDDicd00130, PAS, 1 hit
InterProiView protein in InterPro
IPR000014, PAS
IPR035965, PAS-like_dom_sf
IPR013655, PAS_fold_3
IPR022728, Period_circadian-like_C
PfamiView protein in Pfam
PF08447, PAS_3, 1 hit
PF12114, Period_C, 1 hit
SMARTiView protein in SMART
SM00091, PAS, 2 hits
SUPFAMiSSF55785, SSF55785, 1 hit
PROSITEiView protein in PROSITE
PS50112, PAS, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ6A060_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6A060
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: September 13, 2004
Last sequence update: September 13, 2004
Last modified: April 7, 2021
This is version 86 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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