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Entry version 120 (02 Jun 2021)
Sequence version 2 (26 Feb 2008)
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Protein

Kazrin

Gene

Kazn

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Component of the cornified envelope of keratinocytes. May be involved in the interplay between adherens junctions and desmosomes. The function in the nucleus is not known.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processKeratinization

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-6809371, Formation of the cornified envelope

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Kazrin
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Kazn
Synonyms:Kaz, Kiaa1026
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1918779, Kazn

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cell junction, Cytoplasm, Cytoskeleton, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003224541 – 779KazrinAdd BLAST779

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei356PhosphoserineCombined sources1
Modified residuei371PhosphoserineCombined sources1
Modified residuei391PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q69ZS8

PRoteomics IDEntifications database

More...
PRIDEi
Q69ZS8

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
301746 [Q69ZS8-1]
301747 [Q69ZS8-2]
301748 [Q69ZS8-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q69ZS8

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q69ZS8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in skin interfollicular epidermis and hair follicles. Expressed in tongue epithelium basal suprabasal layers.1 Publication

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed in eggs and early embryos. Detected in unfertilized eggs associated with the spindle apparatus and cytoskeletal sheets. As quickly as 5 min after egg activation, relocates to a diffuse peri-spindle position, followed 20-30 min later by localization to the presumptive cytokinetic ring. Before the blastocyst stage of development, associates with the nuclear matrix in a cell cycle-dependent manner, and also associates with the cytoplasmic actin cytoskeleton. After blastocyst formation, is found associating with cell-cell junctions, the cytoskeleton and nucleus.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000040606, Expressed in striatum and 259 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q69ZS8, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q69ZS8, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
214763, 3 interactors

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000038835

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q69ZS8, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q69ZS8

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini450 – 515SAM 1PROSITE-ProRule annotationAdd BLAST66
Domaini528 – 592SAM 2PROSITE-ProRule annotationAdd BLAST65
Domaini616 – 683SAM 3PROSITE-ProRule annotationAdd BLAST68

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni295 – 366DisorderedSequence analysisAdd BLAST72
Regioni403 – 429DisorderedSequence analysisAdd BLAST27
Regioni685 – 779DisorderedSequence analysisAdd BLAST95

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili79 – 261Sequence analysisAdd BLAST183

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi315 – 366Polar residuesSequence analysisAdd BLAST52
Compositional biasi411 – 426Polar residuesSequence analysisAdd BLAST16
Compositional biasi736 – 764Basic and acidic residuesSequence analysisAdd BLAST29

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the kazrin family.Curated

Keywords - Domaini

Coiled coil, Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0249, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000154570

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q69ZS8

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q69ZS8

TreeFam database of animal gene trees

More...
TreeFami
TF331216

Family and domain databases

Conserved Domains Database

More...
CDDi
cd09564, SAM_kazrin_repeat1, 1 hit
cd09567, SAM_kazrin_repeat2, 1 hit
cd09570, SAM_kazrin_repeat3, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.150.50, 3 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR037614, Kazrin
IPR037613, Kazrin_SAM_rpt_1
IPR037615, Kazrin_SAM_rpt_2
IPR037616, Kazrin_SAM_rpt_3
IPR001660, SAM
IPR013761, SAM/pointed_sf

The PANTHER Classification System

More...
PANTHERi
PTHR12776, PTHR12776, 1 hit

Pfam protein domain database

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Pfami
View protein in Pfam
PF00536, SAM_1, 2 hits
PF07647, SAM_2, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00454, SAM, 3 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47769, SSF47769, 3 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50105, SAM_DOMAIN, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Note: Additional isoforms seem to exist.

This entry has 3 described isoforms and 5 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q69ZS8-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MMEDNKQLAL RIDGAVQSAS QEVTNLRAEL TATNRRLAEL SGGGGGPGSG
60 70 80 90 100
PGAATSASAA AVTVADSAVA TMENHQHGAQ VLLREEVVQL QEEVHLLRQM
110 120 130 140 150
KEMLAKDLEE SQGGKCSEVL SATELRVQLV QKEQELARAK EALQAMKADR
160 170 180 190 200
KRLKGEKTDL VSQMQQLYAT LESREEQLRD FIRNYEQHRK ESEDAVKALA
210 220 230 240 250
KEKDLLEREK WELRRQAKEA TDHAAALRSQ LDLKDNRMKE LEAELAMAKQ
260 270 280 290 300
SLATLTKDVP KRHSLAMPGE TVLNGNQEWV VQADLPLTAA IRQSQQTLYH
310 320 330 340 350
SHPPHPADRQ VRVSPCHSRQ PSVISDASAA EGDRSSTPSD INSPRHRTHS
360 370 380 390 400
LCNGDSPGPV QKSLHNPIVQ SLEDLEDQKR KKKKEKMGFG SISRVFARGK
410 420 430 440 450
QRKSLDPGLF DDSDSQCSPT RHSLSLSEGE EQMDRLQHVE LVRTTPMSHW
460 470 480 490 500
KAGTVQAWLE VVMAMPMYVK ACAENVKSGK VLLSLSDEDL ELGLGVCSSL
510 520 530 540 550
HRRKLRLAIE DYRDAEAGRS LSKAADLDHH WVAKAWLNDI GLSQYSQAFQ
560 570 580 590 600
NHLVDGRMLN SLMKRDLEKH LNVSKKFHQV SILLGIELLY QVNFSREALQ
610 620 630 640 650
ERRARCETQN TDPVVWTNQR VLKWVRDIDL KEYADNLTNS GVHGAVLVLE
660 670 680 690 700
PTFNAEAMAT ALGIPSGKHI LRRHLAEEMS TIFHPSNSTG IRESERFGTP
710 720 730 740 750
PGRASSITRA GREDSGGNSK HRAGRLPLGK IGRGFSSKEP DFHDDYGSLE
760 770
NEDCGDEDLQ GRPEQCRLEG YGSLEVTNV
Length:779
Mass (Da):86,717
Last modified:February 26, 2008 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7A8FBD9D840E4126
GO
Isoform 2 (identifier: Q69ZS8-2) [UniParc]FASTAAdd to basket
Also known as: B

The sequence of this isoform differs from the canonical sequence as follows:
     1-80: MMEDNKQLAL...TMENHQHGAQ → MRAADSGSWE...DAADGFGIQP
     412-425: DSDSQCSPTRHSLS → GTAPDYYIEEDADW
     426-779: Missing.

Show »
Length:414
Mass (Da):46,306
Checksum:i6FCF43B9B12611EE
GO
Isoform 3 (identifier: Q69ZS8-3) [UniParc]FASTAAdd to basket
Also known as: C

The sequence of this isoform differs from the canonical sequence as follows:
     1-99: Missing.
     412-425: DSDSQCSPTRHSLS → GTAPDYYIEEDADW
     426-779: Missing.

Show »
Length:326
Mass (Da):36,950
Checksum:i372515846CED177C
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F6RLJ7F6RLJ7_MOUSE
Kazrin
Kazn
699Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B7ZCA7B7ZCA7_MOUSE
Kazrin
Kazn
261Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
G3UZH4G3UZH4_MOUSE
Kazrin
Kazn
242Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
G3UY74G3UY74_MOUSE
Kazrin
Kazn
425Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
G3UZT9G3UZT9_MOUSE
Kazrin
Kazn
426Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAD32368 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti84R → Q in BAC35155 (PubMed:15368895).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0319041 – 99Missing in isoform 3. 1 PublicationAdd BLAST99
Alternative sequenceiVSP_0319051 – 80MMEDN…QHGAQ → MRAADSGSWERVRQLAAYGQ PTPSCGRDTGSARVPEPGAC KLCADTTGLREQQGAGAVPD AADGFGIQP in isoform 2. 1 PublicationAdd BLAST80
Alternative sequenceiVSP_031906412 – 425DSDSQ…RHSLS → GTAPDYYIEEDADW in isoform 2 and isoform 3. 2 PublicationsAdd BLAST14
Alternative sequenceiVSP_031907426 – 779Missing in isoform 2 and isoform 3. 2 PublicationsAdd BLAST354

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK173090 mRNA Translation: BAD32368.1 Different initiation.
AK052809 mRNA Translation: BAC35155.1
AL663037 Genomic DNA No translation available.
BX537122 Genomic DNA No translation available.
BC022941 mRNA Translation: AAH22941.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS51350.1 [Q69ZS8-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001103154.1, NM_001109684.1
NP_001103155.1, NM_001109685.1 [Q69ZS8-2]
NP_653114.3, NM_144531.3 [Q69ZS8-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000036476; ENSMUSP00000038835; ENSMUSG00000040606 [Q69ZS8-2]
ENSMUST00000155023; ENSMUSP00000116071; ENSMUSG00000040606 [Q69ZS8-1]

Database of genes from NCBI RefSeq genomes

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GeneIDi
71529

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
mmu:71529

UCSC genome browser

More...
UCSCi
uc008vpv.2, mouse [Q69ZS8-1]
uc008vpx.2, mouse [Q69ZS8-2]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK173090 mRNA Translation: BAD32368.1 Different initiation.
AK052809 mRNA Translation: BAC35155.1
AL663037 Genomic DNA No translation available.
BX537122 Genomic DNA No translation available.
BC022941 mRNA Translation: AAH22941.1
CCDSiCCDS51350.1 [Q69ZS8-2]
RefSeqiNP_001103154.1, NM_001109684.1
NP_001103155.1, NM_001109685.1 [Q69ZS8-2]
NP_653114.3, NM_144531.3 [Q69ZS8-1]

3D structure databases

SMRiQ69ZS8
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi214763, 3 interactors
STRINGi10090.ENSMUSP00000038835

PTM databases

iPTMnetiQ69ZS8
PhosphoSitePlusiQ69ZS8

Proteomic databases

PaxDbiQ69ZS8
PRIDEiQ69ZS8
ProteomicsDBi301746 [Q69ZS8-1]
301747 [Q69ZS8-2]
301748 [Q69ZS8-3]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

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Antibodypediai
28740, 106 antibodies

The DNASU plasmid repository

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DNASUi
71529

Genome annotation databases

EnsembliENSMUST00000036476; ENSMUSP00000038835; ENSMUSG00000040606 [Q69ZS8-2]
ENSMUST00000155023; ENSMUSP00000116071; ENSMUSG00000040606 [Q69ZS8-1]
GeneIDi71529
KEGGimmu:71529
UCSCiuc008vpv.2, mouse [Q69ZS8-1]
uc008vpx.2, mouse [Q69ZS8-2]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
23254
MGIiMGI:1918779, Kazn

Rodent Unidentified Gene-Encoded large proteins database

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Rougei
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Phylogenomic databases

eggNOGiKOG0249, Eukaryota
GeneTreeiENSGT00940000154570
InParanoidiQ69ZS8
PhylomeDBiQ69ZS8
TreeFamiTF331216

Enzyme and pathway databases

ReactomeiR-MMU-6809371, Formation of the cornified envelope

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
71529, 0 hits in 18 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
Kazn, mouse

Protein Ontology

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PROi
PR:Q69ZS8
RNActiQ69ZS8, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSMUSG00000040606, Expressed in striatum and 259 other tissues
ExpressionAtlasiQ69ZS8, baseline and differential
GenevisibleiQ69ZS8, MM

Family and domain databases

CDDicd09564, SAM_kazrin_repeat1, 1 hit
cd09567, SAM_kazrin_repeat2, 1 hit
cd09570, SAM_kazrin_repeat3, 1 hit
Gene3Di1.10.150.50, 3 hits
InterProiView protein in InterPro
IPR037614, Kazrin
IPR037613, Kazrin_SAM_rpt_1
IPR037615, Kazrin_SAM_rpt_2
IPR037616, Kazrin_SAM_rpt_3
IPR001660, SAM
IPR013761, SAM/pointed_sf
PANTHERiPTHR12776, PTHR12776, 1 hit
PfamiView protein in Pfam
PF00536, SAM_1, 2 hits
PF07647, SAM_2, 1 hit
SMARTiView protein in SMART
SM00454, SAM, 3 hits
SUPFAMiSSF47769, SSF47769, 3 hits
PROSITEiView protein in PROSITE
PS50105, SAM_DOMAIN, 3 hits

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiKAZRN_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q69ZS8
Secondary accession number(s): A2AC34
, B1B0N1, Q8BIY2, Q8R1X4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: February 26, 2008
Last modified: June 2, 2021
This is version 120 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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