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Protein

Protein FAM214A

Gene

Fam214a

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Protein FAM214A
Gene namesi
Name:Fam214a
Synonyms:Kiaa1370
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 9

Organism-specific databases

MGIiMGI:2387648 Fam214a

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003156141 – 1075Protein FAM214AAdd BLAST1075

Proteomic databases

PaxDbiQ69ZK7
PeptideAtlasiQ69ZK7
PRIDEiQ69ZK7

PTM databases

iPTMnetiQ69ZK7
PhosphoSitePlusiQ69ZK7

Expressioni

Gene expression databases

BgeeiENSMUSG00000034858
CleanExiMM_BC031353
ExpressionAtlasiQ69ZK7 baseline and differential
GenevisibleiQ69ZK7 MM

Family & Domainsi

Sequence similaritiesi

Belongs to the FAM214 family.Curated

Phylogenomic databases

eggNOGiKOG2306 Eukaryota
ENOG41115V6 LUCA
GeneTreeiENSGT00530000063568
HOGENOMiHOG000113164
HOVERGENiHBG108035
InParanoidiQ69ZK7
OMAiQSCYPVT
OrthoDBiEOG091G09N8
TreeFamiTF325496

Family and domain databases

InterProiView protein in InterPro
IPR025261 DUF4210
IPR033473 FAM214/SPAC3H8.04_C
PfamiView protein in Pfam
PF13889 Chromosome_seg, 1 hit
PF13915 DUF4210, 1 hit
SMARTiView protein in SMART
SM01177 DUF4210, 1 hit

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q69ZK7-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MKPDRDALDE YFEYDAEEFL VSLALLITEG RTPECSVKGR AESFHCPPAQ
60 70 80 90 100
SRFPGTARHE CSDKLAQCRQ ARRTRSEVTL LWKNNLPIMV EVMLLPDCCY
110 120 130 140 150
SDEGPSTEGA DLNDPAIKQD ALLLERWILE PVPRQNGDRF IEEKALLLAV
160 170 180 190 200
RSFVFFSQLS AWLSVSHGAI PRNILYRISA ADVDLQWSFS QTPTEHVFPV
210 220 230 240 250
PNVSHNVALK VSVQSLPRQA HYPVLTCSIH TNIGLYEKRI QEQELRACQH
260 270 280 290 300
HGPGEVEYRC PSSSQSLCSK HTWTMAPVSA LHVRSGMPPE YTAAIRNVRL
310 320 330 340 350
CPGTGSKSDQ GAPQASVLGF SGTGGEVRSQ EASVRTFKSL PVVDSSVSSC
360 370 380 390 400
QSSRQPVGEP NPLMDSLIQD RQEVIARIAQ HLIHCDPSSS RMSELPFNTQ
410 420 430 440 450
ESTSLSPKLH PVSQESGCVR RYKEAFSVSF GSPEFGSPGD SREGKVREKS
460 470 480 490 500
ETRPGETCTS HSLYPRQPAG EANPLIGSLL QERQDVIARI AQHLEHIDPA
510 520 530 540 550
AHIPRPAFSK HDSNSIPSKV FRSSFDDKTL LKKGRENVSV SVSHTEVSLL
560 570 580 590 600
GDRGDGESLK PSKCLRSFKY SPQEKPLKPE VRTQHQNHPD SITPTARQEL
610 620 630 640 650
LNKAAGLLTS SNTALCKESS LGLVSRLEST SCKLQLKEQE MSHETEKQCL
660 670 680 690 700
HCNSIDKQIC TNTCTEKIND EHSPGSLRHL QCDDSKGIDS KLKVTLLEMP
710 720 730 740 750
DSLNKNKTNC SSKDSKRSKT CEQSIRVGTE NDLSEENEGP GSTVSDRLKT
760 770 780 790 800
EQEAKRDSGA GKPHSVKHCL SAGERLHSAD MLRTTLKHSS VWRKHNFHSL
810 820 830 840 850
DGTSTRAFHP QTGLPLLSSP VPQRKTQSGC FDLDASLLHL RSLSSKSSRP
860 870 880 890 900
CLNIDEDPDV HEKPFLSSSA PPITSLSLLG NFEESVLNYR LDPLGIVDGF
910 920 930 940 950
TAEVGASGTF CPTHLTLPVE VSFYSVSDDN APSPYMGVIT LESLGKRGYR
960 970 980 990 1000
VPPSGTIQVT LFNPNKTVVK MFVVVYDLRG MPANHQTFLR QRTFSVPVKQ
1010 1020 1030 1040 1050
EMKRSINKEN VQHTAQLLRY LIHLRFQSSK SGKIYLHRDV RLLFSRKSME
1060 1070
VDSGAAYELK SYTESPTNPQ FSPRC
Length:1,075
Mass (Da):119,272
Last modified:July 27, 2011 - v3
Checksum:i273531DB7746D718
GO
Isoform 2 (identifier: Q69ZK7-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-5: MKPDR → MVFSGNKGLRRQ

Note: No experimental confirmation available.
Show »
Length:1,082
Mass (Da):120,018
Checksum:iEC38C680EF77D64E
GO

Sequence cautioni

The sequence AAH32966 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence BAD32439 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti100Y → F in AAH31353 (PubMed:15489334).Curated1
Sequence conflicti617K → N in BAD32439 (PubMed:15368895).Curated1
Sequence conflicti658Q → H in BAD32439 (PubMed:15368895).Curated1
Sequence conflicti710C → Y in AAH32966 (PubMed:15489334).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0305821 – 5MKPDR → MVFSGNKGLRRQ in isoform 2. 1 Publication5

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK173161 Transcribed RNA Translation: BAD32439.1 Different initiation.
CT025657 Genomic DNA No translation available.
CT033761 Genomic DNA No translation available.
BC031353 mRNA Translation: AAH31353.1
BC032966 mRNA Translation: AAH32966.1 Different initiation.
CCDSiCCDS52857.1 [Q69ZK7-1]
CCDS52858.1 [Q69ZK7-2]
RefSeqiNP_001106754.1, NM_001113283.1 [Q69ZK7-1]
NP_705812.2, NM_153584.2 [Q69ZK7-2]
XP_006511189.1, XM_006511126.3 [Q69ZK7-1]
XP_006511190.1, XM_006511127.3
UniGeneiMm.208955

Genome annotation databases

EnsembliENSMUST00000081746; ENSMUSP00000080442; ENSMUSG00000034858 [Q69ZK7-2]
ENSMUST00000170846; ENSMUSP00000129319; ENSMUSG00000034858 [Q69ZK7-1]
ENSMUST00000215370; ENSMUSP00000149021; ENSMUSG00000034858 [Q69ZK7-1]
GeneIDi235493
KEGGimmu:235493
UCSCiuc009qrl.2 mouse [Q69ZK7-2]
uc012gww.1 mouse [Q69ZK7-1]

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Entry informationi

Entry nameiF214A_MOUSE
AccessioniPrimary (citable) accession number: Q69ZK7
Secondary accession number(s): E9PX00, Q8K0I6, Q8K266
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 27, 2011
Last modified: June 20, 2018
This is version 75 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

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