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UniProtKB - Q69572 (GQ1_HHV6U)
Protein
Glycoprotein Q1
Gene
U100
Organism
Human herpesvirus 6A (strain Uganda-1102) (HHV-6 variant A) (Human B lymphotropic virus)
Status
Functioni
Plays a role in virus entry by participating in host receptor binding at the cell surface.
3 PublicationsGO - Biological processi
- entry receptor-mediated virion attachment to host cell Source: UniProtKB-KW
- viral entry into host cell Source: UniProtKB-KW
Keywordsi
Biological process | Host-virus interaction, Viral attachment to host cell, Viral attachment to host entry receptor, Virus entry into host cell |
Names & Taxonomyi
Protein namesi | Recommended name: Glycoprotein Q1Short name: gQ1 Alternative name(s): Glycoprotein 105 Short name: gp105 Glycoprotein Q-80k Short name: gQ-80k HCLF1 protein |
Gene namesi | ORF Names:U100 |
Organismi | Human herpesvirus 6A (strain Uganda-1102) (HHV-6 variant A) (Human B lymphotropic virus) |
Taxonomic identifieri | 10370 [NCBI] |
Taxonomic lineagei | Viruses › Duplodnaviria › Heunggongvirae › Peploviricota › Herviviricetes › Herpesvirales › Herpesviridae › Betaherpesvirinae › Roseolovirus › |
Virus hosti | Homo sapiens (Human) [TaxID: 9606] |
Proteomesi |
|
Subcellular locationi
Other locations
- Virion
- Host endoplasmic reticulum lumen 1 Publication
Other locations
- host cell endoplasmic reticulum lumen Source: UniProtKB-SubCell
- viral envelope Source: UniProtKB-KW
Keywords - Cellular componenti
Host endoplasmic reticulum, Viral envelope protein, VirionPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 32 | Sequence analysisAdd BLAST | 32 | |
ChainiPRO_0000343642 | 33 – 524 | Glycoprotein Q11 PublicationAdd BLAST | 492 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Glycosylationi | 290 | N-linked (GlcNAc...) asparagine; by hostPROSITE-ProRule annotation | 1 | |
Glycosylationi | 332 | N-linked (GlcNAc...) asparagine; by hostPROSITE-ProRule annotation | 1 | |
Glycosylationi | 338 | N-linked (GlcNAc...) asparagine; by hostPROSITE-ProRule annotation | 1 | |
Glycosylationi | 359 | N-linked (GlcNAc...) asparagine; by hostPROSITE-ProRule annotation | 1 | |
Glycosylationi | 422 | N-linked (GlcNAc...) asparagine; by hostPROSITE-ProRule annotation | 1 |
Post-translational modificationi
Glycosylated by host.2 Publications
Keywords - PTMi
GlycoproteinProteomic databases
PRIDEi | Q69572 |
Interactioni
Subunit structurei
Structurei
s (3)i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
This entry describes 3 produced by isoformsialternative splicing. AlignAdd to basketIsoform Glycoprotein Q11 Publication (identifier: Q69572-1) [UniParc]FASTAAdd to basket
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MATARLSAMK PPRSCALIFL CAFSMATAPT NATAHRRAGT VKSTPPPEDK
60 70 80 90 100
HSYTAKYYDK DIYFNIYEGR NSTPRRRTLS EIISKFSTSE MLSLKRVKAF
110 120 130 140 150
VPVDENPTTT LEDIADILNY AVCDDNSCGC TIETQARIMF GDIIICVPLS
160 170 180 190 200
ADNKGVRNFK DRIMPKGLSQ ILSSSLGLHL SLLYGAFGSN YNSLAYMRRL
210 220 230 240 250
KPLTAMTAIR FCPMTTKLEL RQNYKVKETL CELIVSIEIL KIRNNGGQTM
260 270 280 290 300
KTLTSFAIVR KDNDGQDWET CTRFAPVNIE DILRYKRVAN DTCCRHRDVQ
310 320 330 340 350
HGRRTLESSN SWTQTQYFEP WQDIVDVYVP INDTHCPNDS YVVFETLQGF
360 370 380 390 400
EWCSRLNKNE TKNYLSSVLG FRNALFETEE LMETIAMRLA SQILSMVGQQ
410 420 430 440 450
GTTIRDIDPA IVSALWHSLP ENLTTTNIKY DIASPTHMRP ALCTIFVQTG
460 470 480 490 500
TSKQRFRNAG LLMVNNIFTV QGRYTTQNMF ERKEYVYKHL GQALCQGGHV
510 520
FYNPKEVKSE NIKMINIKPT VVRT
Note: Transcribed from a highly spliced mRNA.
Isoform Glycoprotein Q21 Publication (identifier: P0DOE0-1) [UniParc]FASTAAdd to basket
The sequence of this isoform can be found in the external entry P0DOE0.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Isoform Glycoprotein Q01 Publication (identifier: P0DOE0-2) [UniParc]FASTAAdd to basket
The sequence of this isoform can be found in the external entry P0DOE0.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Sequence cautioni
The sequence BAA01908 differs from that shown. Reason: Erroneous gene model prediction.1 Publication
The sequence CAA58346 differs from that shown. Reason: Erroneous gene model prediction.1 Publication
The sequence CAA58347 differs from that shown. Reason: Erroneous gene model prediction.1 Publication
The sequence CAA58348 differs from that shown. Reason: Erroneous gene model prediction.1 Publication
The sequence CAA58349 differs from that shown. Reason: Erroneous gene model prediction.1 Publication
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D11134 Genomic DNA Translation: BAA01908.1 Sequence problems. X83413 Genomic DNA Translation: CAA58346.1 Sequence problems. X83413 Genomic DNA Translation: CAA58347.1 Sequence problems. X83413 Genomic DNA Translation: CAA58348.1 Sequence problems. X83413 Genomic DNA Translation: CAA58349.1 Sequence problems. |
PIRi | JQ1632 |
RefSeqi | NP_042993.3, NC_001664.2 |
Genome annotation databases
GeneIDi | 1487972 |
KEGGi | vg:1487972 |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D11134 Genomic DNA Translation: BAA01908.1 Sequence problems. X83413 Genomic DNA Translation: CAA58346.1 Sequence problems. X83413 Genomic DNA Translation: CAA58347.1 Sequence problems. X83413 Genomic DNA Translation: CAA58348.1 Sequence problems. X83413 Genomic DNA Translation: CAA58349.1 Sequence problems. |
PIRi | JQ1632 |
RefSeqi | NP_042993.3, NC_001664.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PRIDEi | Q69572 |
Protocols and materials databases
DNASUi | 1487972 |
Genome annotation databases
GeneIDi | 1487972 |
KEGGi | vg:1487972 |
Family and domain databases
MobiDBi | Search... |
Entry informationi
Entry namei | GQ1_HHV6U | |
Accessioni | Q69572Primary (citable) accession number: Q69572 Secondary accession number(s): Q69573 Q76WN9 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 22, 2008 |
Last sequence update: | November 2, 2016 | |
Last modified: | June 2, 2021 | |
This is version 65 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Viral Protein Annotation Program |