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Entry version 129 (13 Nov 2019)
Sequence version 1 (11 Oct 2004)
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Protein

Methionine--tRNA ligase, cytoplasmic

Gene

Mars

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. Plays a role in the synthesis of ribosomal RNA in the nucleolus.By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei598ATPBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase, RNA-binding, tRNA-binding
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Methionine--tRNA ligase, cytoplasmic (EC:6.1.1.10By similarity)
Alternative name(s):
Methionyl-tRNA synthetase
Short name:
MetRS
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Mars
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1345633 Mars

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001392631 – 902Methionine--tRNA ligase, cytoplasmicAdd BLAST902

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei827PhosphoserineCombined sources1
Modified residuei837PhosphothreonineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q68FL6

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q68FL6

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q68FL6

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q68FL6

PeptideAtlas

More...
PeptideAtlasi
Q68FL6

PRoteomics IDEntifications database

More...
PRIDEi
Q68FL6

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q68FL6

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q68FL6

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q68FL6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000040354 Expressed in 281 organ(s), highest expression level in midbrain

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q68FL6 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q68FL6 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Monomer.

Part of a multisubunit complex that groups tRNA ligases for Arg (RARS), Asp (DARS), Gln (QARS), Ile (IARS), Leu (LARS), Lys (KARS1), Met (MARS) the bifunctional ligase for Glu and Pro (EPRS) and the auxiliary subunits AIMP1/p43, AIMP2/p38 and EEF1E1/p18.

Forms a linear complex that contains MARS, EEF1E1, EPRS and AIMP2 that is at the core of the multisubunit complex.

1 Publication

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
229747, 3 interactors

Protein interaction database and analysis system

More...
IntActi
Q68FL6, 1 interactor

Molecular INTeraction database

More...
MINTi
Q68FL6

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000037446

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q68FL6

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini74 – 212GST C-terminalAdd BLAST139
Domaini843 – 899WHEP-TRSAdd BLAST57

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi275 – 285'HIGH' regionAdd BLAST11
Motifi595 – 599'KMSKS' region5

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0867 Eukaryota
KOG1247 Eukaryota
COG0143 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00550000075017

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000200402

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q68FL6

KEGG Orthology (KO)

More...
KOi
K01874

Identification of Orthologs from Complete Genome Data

More...
OMAi
CANIACL

Database of Orthologous Groups

More...
OrthoDBi
333013at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q68FL6

TreeFam database of animal gene trees

More...
TreeFami
TF300526

Family and domain databases

Conserved Domains Database

More...
CDDi
cd07957 Anticodon_Ia_Met, 1 hit
cd00814 MetRS_core, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.20.28.20, 1 hit
3.40.30.10, 1 hit
3.40.50.620, 1 hit

HAMAP database of protein families

More...
HAMAPi
MF_00098 Met_tRNA_synth_type1, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR041872 Anticodon_Met
IPR010987 Glutathione-S-Trfase_C-like
IPR036282 Glutathione-S-Trfase_C_sf
IPR004046 GST_C
IPR041598 MARS_N
IPR023458 Met-tRNA_ligase_1
IPR014758 Met-tRNA_synth
IPR015413 Methionyl/Leucyl_tRNA_Synth
IPR033911 MetRS_core
IPR029038 MetRS_Zn
IPR014729 Rossmann-like_a/b/a_fold
IPR009068 S15_NS1_RNA-bd
IPR036249 Thioredoxin-like_sf
IPR009080 tRNAsynth_Ia_anticodon-bd
IPR000738 WHEP-TRS_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00043 GST_C, 1 hit
PF18485 GST_N_5, 1 hit
PF09334 tRNA-synt_1g, 1 hit
PF00458 WHEP-TRS, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01041 TRNASYNTHMET

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00991 WHEP-TRS, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47060 SSF47060, 1 hit
SSF47323 SSF47323, 1 hit
SSF47616 SSF47616, 1 hit
SSF57770 SSF57770, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00398 metG, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit
PS50405 GST_CTER, 1 hit
PS00762 WHEP_TRS_1, 1 hit
PS51185 WHEP_TRS_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q68FL6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRLFVSEGSP GSLPVLAAAA RARGRAELLI STVGPEECVV PFLTRPKVPV
60 70 80 90 100
LQLDSGNYLF SASAICRYFF LLCGWEQDDL TNQWLEWEAT ELQPVLSAAL
110 120 130 140 150
HCLVVQGKKG EDILGPLRRV LTHIDHSLSR QNCPFLAGDT ESLADIVLWG
160 170 180 190 200
ALYPLLQDPA YLPEELGALQ SWFQTLSTQE PCQRAAETVL KQQGVLALRL
210 220 230 240 250
YLQKQPQPQP PPPEGRTVSN ELEEEELATL SEEDIVTAVA AWEKGLESLP
260 270 280 290 300
PLKLQQHPVL PVPGERNVLI TSALPYVNNV PHLGNIIGCV LSADVFARYC
310 320 330 340 350
RLRQWNTLYL CGTDEYGTAT ETKAMEEGLT PREICDKYHA IHADIYRWFG
360 370 380 390 400
ISFDTFGRTT TPQQTKITQD IFQRLLTRGF VLRDTVEQLR CERCARFLAD
410 420 430 440 450
RFVEGVCPFC GYEEARGDQC DRCGKLINAI ELKKPQCKIC RSCPVVRSSQ
460 470 480 490 500
HLFLDLPKLE KRLEDWLGKT VPGSDWTPNA RFIIRSWLRD GLKPRCITRD
510 520 530 540 550
LKWGTPVPLE GFEDKVFYVW FDATIGYVSI TANYTDQWEK WWKNPEQVDL
560 570 580 590 600
YQFMAKDNVP FHGLVFPCSV LGAEDNYTLV KHIIATEYLN YEDGKFSKSR
610 620 630 640 650
GIGVFGDMAK DTGIPADIWR FYLLYIRPEG QDSAFSWTDL LIKNNSELLN
660 670 680 690 700
NLGNFINRAG MFVSKFFGGC VPEMALTPDD RRLVAHVSWE LQHYHQLLEK
710 720 730 740 750
VRIRDALRSI LTISRHGNQY IQVNEPWKRI KGGEMDRQRA GTVTGMAVNM
760 770 780 790 800
AALLSVMLQP YMPTVSSTIQ TQLQLPPAAC RILATSFICT LPAGHRIGTV
810 820 830 840 850
SPLFQKLEND QIENLRQRFG GGQAKGSPKP AAVEAVTAAG SQHIQTLTDE
860 870 880 890 900
VTKQGNVVRE LKAQKADKNQ VAAEVAKLLD LKKQLALAEG KPIETPKGKK

KK
Length:902
Mass (Da):101,431
Last modified:October 11, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iACCE81F1D8049027
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9QB02E9QB02_MOUSE
Methionine--tRNA ligase, cytoplasmi...
Mars
910Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6W0G8F6W0G8_MOUSE
Methionine--tRNA ligase, cytoplasmi...
Mars
184Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BC079643 mRNA Translation: AAH79643.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS24237.1

NCBI Reference Sequences

More...
RefSeqi
NP_001003913.1, NM_001003913.2
NP_001165053.1, NM_001171582.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000037290; ENSMUSP00000037446; ENSMUSG00000040354

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
216443

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:216443

UCSC genome browser

More...
UCSCi
uc007hiz.2 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC079643 mRNA Translation: AAH79643.1
CCDSiCCDS24237.1
RefSeqiNP_001003913.1, NM_001003913.2
NP_001165053.1, NM_001171582.1

3D structure databases

SMRiQ68FL6
ModBaseiSearch...

Protein-protein interaction databases

BioGridi229747, 3 interactors
IntActiQ68FL6, 1 interactor
MINTiQ68FL6
STRINGi10090.ENSMUSP00000037446

PTM databases

iPTMnetiQ68FL6
PhosphoSitePlusiQ68FL6
SwissPalmiQ68FL6

Proteomic databases

EPDiQ68FL6
jPOSTiQ68FL6
MaxQBiQ68FL6
PaxDbiQ68FL6
PeptideAtlasiQ68FL6
PRIDEiQ68FL6

Genome annotation databases

EnsembliENSMUST00000037290; ENSMUSP00000037446; ENSMUSG00000040354
GeneIDi216443
KEGGimmu:216443
UCSCiuc007hiz.2 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
216443
MGIiMGI:1345633 Mars

Phylogenomic databases

eggNOGiKOG0867 Eukaryota
KOG1247 Eukaryota
COG0143 LUCA
GeneTreeiENSGT00550000075017
HOGENOMiHOG000200402
InParanoidiQ68FL6
KOiK01874
OMAiCANIACL
OrthoDBi333013at2759
PhylomeDBiQ68FL6
TreeFamiTF300526

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Mars mouse

Protein Ontology

More...
PROi
PR:Q68FL6

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000040354 Expressed in 281 organ(s), highest expression level in midbrain
ExpressionAtlasiQ68FL6 baseline and differential
GenevisibleiQ68FL6 MM

Family and domain databases

CDDicd07957 Anticodon_Ia_Met, 1 hit
cd00814 MetRS_core, 1 hit
Gene3Di2.20.28.20, 1 hit
3.40.30.10, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00098 Met_tRNA_synth_type1, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR041872 Anticodon_Met
IPR010987 Glutathione-S-Trfase_C-like
IPR036282 Glutathione-S-Trfase_C_sf
IPR004046 GST_C
IPR041598 MARS_N
IPR023458 Met-tRNA_ligase_1
IPR014758 Met-tRNA_synth
IPR015413 Methionyl/Leucyl_tRNA_Synth
IPR033911 MetRS_core
IPR029038 MetRS_Zn
IPR014729 Rossmann-like_a/b/a_fold
IPR009068 S15_NS1_RNA-bd
IPR036249 Thioredoxin-like_sf
IPR009080 tRNAsynth_Ia_anticodon-bd
IPR000738 WHEP-TRS_dom
PfamiView protein in Pfam
PF00043 GST_C, 1 hit
PF18485 GST_N_5, 1 hit
PF09334 tRNA-synt_1g, 1 hit
PF00458 WHEP-TRS, 1 hit
PRINTSiPR01041 TRNASYNTHMET
SMARTiView protein in SMART
SM00991 WHEP-TRS, 1 hit
SUPFAMiSSF47060 SSF47060, 1 hit
SSF47323 SSF47323, 1 hit
SSF47616 SSF47616, 1 hit
SSF57770 SSF57770, 1 hit
TIGRFAMsiTIGR00398 metG, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit
PS50405 GST_CTER, 1 hit
PS00762 WHEP_TRS_1, 1 hit
PS51185 WHEP_TRS_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSYMC_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q68FL6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 13, 2005
Last sequence update: October 11, 2004
Last modified: November 13, 2019
This is version 129 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families
  3. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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