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Entry version 135 (12 Aug 2020)
Sequence version 1 (11 Oct 2004)
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Protein

Teashirt homolog 2

Gene

Tshz2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Probable transcriptional regulator involved in developmental processes. May act as a transcriptional repressor (Potential).Curated

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri216 – 240C2H2-type 1PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri276 – 300C2H2-type 2PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri381 – 405C2H2-type 3; atypicalPROSITE-ProRule annotationAdd BLAST25
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position and type of each DNA-binding domain present within the protein.<p><a href='/help/dna_bind' target='_top'>More...</a></p>DNA bindingi837 – 907HomeoboxAdd BLAST71
Zinc fingeri922 – 944C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri990 – 1013C2H2-type 5PROSITE-ProRule annotationAdd BLAST24

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDevelopmental protein, DNA-binding, Repressor
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Teashirt homolog 2
Alternative name(s):
SDCCAG33-like protein
Zinc finger protein 218
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Tshz2
Synonyms:Kiaa4248, Sdccag33l, Tsh2, Zfp218, Znf218
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2153084, Tshz2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000470651 – 1030Teashirt homolog 2Add BLAST1030

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki189Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki307Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki316Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki418Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki462Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki480Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki497Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki601Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki652Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki796Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki816Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki962Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei976PhosphoserineCombined sources1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Sumoylated.By similarity

Keywords - PTMi

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q68FE9

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q68FE9

PRoteomics IDEntifications database

More...
PRIDEi
Q68FE9

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q68FE9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q68FE9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed in mesenchymal cells in proximal ureters at 14 dpc, preceding the smooth muscle precursor cells differentiation and the expression of contractile proteins from 15 dpc.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000047907, Expressed in olfactory epithelium and 251 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q68FE9, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q68FE9, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts (via homeobox domain) with APBB1 (via PID domain 1).

1 Publication

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
230794, 1 interactor

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000104785

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q68FE9, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q68FE9

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili11 – 42Sequence analysisAdd BLAST32

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri216 – 240C2H2-type 1PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri276 – 300C2H2-type 2PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri381 – 405C2H2-type 3; atypicalPROSITE-ProRule annotationAdd BLAST25
Zinc fingeri922 – 944C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri990 – 1013C2H2-type 5PROSITE-ProRule annotationAdd BLAST24

Keywords - Domaini

Coiled coil, Homeobox, Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QV71, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000183051

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_010469_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q68FE9

KEGG Orthology (KO)

More...
KOi
K09236

Identification of Orthologs from Complete Genome Data

More...
OMAi
MKYQYLR

Database of Orthologous Groups

More...
OrthoDBi
106971at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q68FE9

TreeFam database of animal gene trees

More...
TreeFami
TF328447

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00086, homeodomain, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001356, Homeobox_dom
IPR027008, Teashirt_fam
IPR027010, Tshz2
IPR013087, Znf_C2H2_type

The PANTHER Classification System

More...
PANTHERi
PTHR12487, PTHR12487, 1 hit
PTHR12487:SF3, PTHR12487:SF3, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00389, HOX, 1 hit
SM00355, ZnF_C2H2, 5 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 4 hits
PS50157, ZINC_FINGER_C2H2_2, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

Q68FE9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPRRKQQAPK RAAGYAQEEV LKEEEEIKEE EEEEEDSGSV AQHQSSNDTG
60 70 80 90 100
TDEELETGPE QKGYFSCQNS PGSHLSNQDA ENESLLSDAS DQVSDVKSVC
110 120 130 140 150
GRDVSDKKAN THPKLPSEPH NCMDKMTAVY ANILSDSYWS GLGLGFKLSN
160 170 180 190 200
SERRNCDTRN SSGKNDFDWH QDALSKSLQQ NLPSRSVSKP SLFSSVQLYR
210 220 230 240 250
QSSKLCGSVF TGASRFRCRQ CSAAYDTLVE LTVHMNETGH YQDDNRKKDK
260 270 280 290 300
LRPTSYSKPR KRAFQDMDKE DAQKVLKCMF CGDSFDSLQD LSVHMIKTKH
310 320 330 340 350
YQKVPLKEPV PTISSKMVTP AKKRVFDVNR PCSPDSTTGS LADSFSSQKS
360 370 380 390 400
ANLQLPSNSR YGYQNGASYT WQFEACKSQI LKCMECGSSH DTLQQLTTHM
410 420 430 440 450
MVTGHFLKVT SSASKKGKQL VLDPLAVEKM QSLSETPNSE SLAPKPSSNS
460 470 480 490 500
PSECTASTTE LKKESKKEKG EGIEDEQGVK SEDYEDSLQK PLDPTIKYQY
510 520 530 540 550
LREEDLEDGS KGGGDILKSL ENTVTTAINK AQNGAPSWSA YPSIHAAYQL
560 570 580 590 600
SEGTKPPMAM GSQILQIRPN LANKLRPIAP KWKGMPLGPV PTSLALYTQV
610 620 630 640 650
KKETEDKDEV VKQCGKESPH EEATSFSQPE GESFSKIEPP SESRKAEPCP
660 670 680 690 700
LKEEEKPQKE KPEPLEPVSS LTNGCAPANH TPALPSINPL SALQSVLNNH
710 720 730 740 750
LGKATEPLRS PSCSSPNSST SPVFHKSSLH VVDKPVISPT STRPAASVAR
760 770 780 790 800
HYLFENTDQP IDLTKSKSKR AESSQAQSCT SPPQKHALCD IADMVKVLPK
810 820 830 840 850
ATTPKPAASS RVPPMKLEID VRRFEDVSSE VSTLHKRKGR QSNWNPQHLL
860 870 880 890 900
ILQAQFASSL FQTSEGKYLL SDLGPQERMQ ISKFTGLSMT TISHWLANVK
910 920 930 940 950
YQLRKTGGTK FLKNMDKGHP IFYCSDCASQ FRTPSTYISH LESHLGFQMK
960 970 980 990 1000
DMTRMAADQQ SKVEQEISRV SSAQRSPETI AGEEDTDSKF KCKLCRRTFV
1010 1020 1030
SKHAVKLHLS KTHSKSPEHH SQFVADVDEE
Length:1,030
Mass (Da):114,223
Last modified:October 11, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1F8075095AE4D60E
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q8K350Q8K350_MOUSE
Teashirt homolog 2
Tshz2 Sdccag33l, Zfp218
208Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WS38A0A087WS38_MOUSE
Teashirt homolog 2
Tshz2
522Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0A0MQI3A0A0A0MQI3_MOUSE
Teashirt homolog 2
Tshz2
561Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAF64095 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated
The sequence BAD90333 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti159 – 227Missing in AAH79550 (PubMed:15489334).CuratedAdd BLAST69
Sequence conflicti607K → R in AAF64095 (PubMed:10704881).Curated1
Sequence conflicti1012T → A in AAF64095 (PubMed:10704881).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BC079877 mRNA Translation: AAH79877.1
BC079550 mRNA Translation: AAH79550.1
AK220569 mRNA Translation: BAD90333.1 Different initiation.
AF207880 Genomic DNA Translation: AAF64095.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS50805.1

NCBI Reference Sequences

More...
RefSeqi
NP_536703.2, NM_080455.2
XP_011237817.1, XM_011239515.2
XP_017173455.1, XM_017317966.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000109157; ENSMUSP00000104785; ENSMUSG00000047907
ENSMUST00000109159; ENSMUSP00000104787; ENSMUSG00000047907

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
228911

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:228911

UCSC genome browser

More...
UCSCi
uc008obo.2, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC079877 mRNA Translation: AAH79877.1
BC079550 mRNA Translation: AAH79550.1
AK220569 mRNA Translation: BAD90333.1 Different initiation.
AF207880 Genomic DNA Translation: AAF64095.1 Different initiation.
CCDSiCCDS50805.1
RefSeqiNP_536703.2, NM_080455.2
XP_011237817.1, XM_011239515.2
XP_017173455.1, XM_017317966.1

3D structure databases

SMRiQ68FE9
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi230794, 1 interactor
STRINGi10090.ENSMUSP00000104785

PTM databases

iPTMnetiQ68FE9
PhosphoSitePlusiQ68FE9

Proteomic databases

MaxQBiQ68FE9
PaxDbiQ68FE9
PRIDEiQ68FE9

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
52541, 112 antibodies

Genome annotation databases

EnsembliENSMUST00000109157; ENSMUSP00000104785; ENSMUSG00000047907
ENSMUST00000109159; ENSMUSP00000104787; ENSMUSG00000047907
GeneIDi228911
KEGGimmu:228911
UCSCiuc008obo.2, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
128553
MGIiMGI:2153084, Tshz2

Rodent Unidentified Gene-Encoded large proteins database

More...
Rougei
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Phylogenomic databases

eggNOGiENOG502QV71, Eukaryota
GeneTreeiENSGT00950000183051
HOGENOMiCLU_010469_0_0_1
InParanoidiQ68FE9
KOiK09236
OMAiMKYQYLR
OrthoDBi106971at2759
PhylomeDBiQ68FE9
TreeFamiTF328447

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
228911, 0 hits in 18 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
Tshz2, mouse

Protein Ontology

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PROi
PR:Q68FE9
RNActiQ68FE9, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSMUSG00000047907, Expressed in olfactory epithelium and 251 other tissues
ExpressionAtlasiQ68FE9, baseline and differential
GenevisibleiQ68FE9, MM

Family and domain databases

CDDicd00086, homeodomain, 1 hit
InterProiView protein in InterPro
IPR001356, Homeobox_dom
IPR027008, Teashirt_fam
IPR027010, Tshz2
IPR013087, Znf_C2H2_type
PANTHERiPTHR12487, PTHR12487, 1 hit
PTHR12487:SF3, PTHR12487:SF3, 1 hit
SMARTiView protein in SMART
SM00389, HOX, 1 hit
SM00355, ZnF_C2H2, 5 hits
PROSITEiView protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 4 hits
PS50157, ZINC_FINGER_C2H2_2, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTSH2_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q68FE9
Secondary accession number(s): Q5DTF1, Q6AXH5, Q9JL71
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 10, 2006
Last sequence update: October 11, 2004
Last modified: August 12, 2020
This is version 135 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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