UniProtKB - Q68FB1 (BOD1_XENTR)
Protein
Biorientation of chromosomes in cell division protein 1
Gene
bod1
Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Functioni
Required for proper chromosome biorientation through the detection or correction of syntelic attachments in mitotic spindles.By similarity
GO - Molecular functioni
- protein phosphatase 2A binding Source: GO_Central
- protein phosphatase inhibitor activity Source: GO_Central
GO - Biological processi
- cell cycle Source: UniProtKB-KW
- cell division Source: UniProtKB-KW
- negative regulation of phosphoprotein phosphatase activity Source: GO_Central
Keywordsi
Biological process | Cell cycle, Cell division, Mitosis |
Names & Taxonomyi
Protein namesi | Recommended name: Biorientation of chromosomes in cell division protein 1Alternative name(s): Biorientation defective protein 1 Protein FAM44B |
Gene namesi | Name:bod1 Synonyms:fam44b ORF Names:TEgg028l03.1 |
Organismi | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) |
Taxonomic identifieri | 8364 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Amphibia › Batrachia › Anura › Pipoidea › Pipidae › Xenopodinae › Xenopus › Silurana |
Proteomesi |
|
Organism-specific databases
Xenbasei | XB-GENE-5810100, bod1 |
Subcellular locationi
Cytoskeleton
- centrosome By similarity
Other locations
- kinetochore By similarity
Note: Localizes at the centrosomes throughout the cell cycle, only dissociating during cytokinesis. Localizes at the kinetochore from prometaphase until anaphase.By similarity
Cytoskeleton
- centrosome Source: GO_Central
- spindle microtubule Source: GO_Central
- spindle pole Source: GO_Central
Other locations
- condensed chromosome outer kinetochore Source: GO_Central
- cytoplasm Source: UniProtKB-KW
Keywords - Cellular componenti
Centromere, Chromosome, Cytoplasm, Cytoskeleton, KinetochorePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000187032 | 1 – 169 | Biorientation of chromosomes in cell division protein 1Add BLAST | 169 |
Proteomic databases
PaxDbi | Q68FB1 |
Expressioni
Gene expression databases
Bgeei | ENSXETG00000022543, Expressed in embryo and 12 other tissues |
Interactioni
GO - Molecular functioni
- protein phosphatase 2A binding Source: GO_Central
Protein-protein interaction databases
STRINGi | 8364.ENSXETP00000048799 |
Family & Domainsi
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 145 – 164 | Pro-richAdd BLAST | 20 |
Sequence similaritiesi
Belongs to the BOD1 family.Curated
Phylogenomic databases
eggNOGi | ENOG502S57W, Eukaryota |
GeneTreei | ENSGT00940000154979 |
HOGENOMi | CLU_139504_0_0_1 |
InParanoidi | Q68FB1 |
OMAi | LSTQEWN |
OrthoDBi | 1333373at2759 |
TreeFami | TF325311 |
Family and domain databases
InterProi | View protein in InterPro IPR026955, Bod1-like |
PANTHERi | PTHR31532, PTHR31532, 1 hit |
i Sequence
Sequence statusi: Complete.
Q68FB1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAESGSGAGS GSSSVGGVSN PTSLAPGDSQ LIALIVEQLK SRGQFDGFRR
60 70 80 90 100
DCLADVDTKP AYQNLRQKVD NFVSTHLDKQ EWNADMNKNQ LRNGLRQSVI
110 120 130 140 150
QSGMLEAGVD RIISQVVDPK LNHIFRPQIE KAIQEYLAAQ TKEEPAPPLP
160
PGPPEPQEQE PPGPSQSVS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CR761021 mRNA Translation: CAJ81950.1 BC079931 mRNA Translation: AAH79931.1 |
RefSeqi | NP_001007495.1, NM_001007494.1 XP_012810034.1, XM_012954580.2 XP_012810035.1, XM_012954581.2 XP_012810036.1, XM_012954582.2 XP_012810037.1, XM_012954583.2 XP_017945730.1, XM_018090241.1 |
Genome annotation databases
Ensembli | ENSXETT00000048799; ENSXETP00000048799; ENSXETG00000022543 |
GeneIDi | 493221 |
KEGGi | xtr:493221 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CR761021 mRNA Translation: CAJ81950.1 BC079931 mRNA Translation: AAH79931.1 |
RefSeqi | NP_001007495.1, NM_001007494.1 XP_012810034.1, XM_012954580.2 XP_012810035.1, XM_012954581.2 XP_012810036.1, XM_012954582.2 XP_012810037.1, XM_012954583.2 XP_017945730.1, XM_018090241.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 8364.ENSXETP00000048799 |
Proteomic databases
PaxDbi | Q68FB1 |
Genome annotation databases
Ensembli | ENSXETT00000048799; ENSXETP00000048799; ENSXETG00000022543 |
GeneIDi | 493221 |
KEGGi | xtr:493221 |
Organism-specific databases
CTDi | 91272 |
Xenbasei | XB-GENE-5810100, bod1 |
Phylogenomic databases
eggNOGi | ENOG502S57W, Eukaryota |
GeneTreei | ENSGT00940000154979 |
HOGENOMi | CLU_139504_0_0_1 |
InParanoidi | Q68FB1 |
OMAi | LSTQEWN |
OrthoDBi | 1333373at2759 |
TreeFami | TF325311 |
Gene expression databases
Bgeei | ENSXETG00000022543, Expressed in embryo and 12 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR026955, Bod1-like |
PANTHERi | PTHR31532, PTHR31532, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | BOD1_XENTR | |
Accessioni | Q68FB1Primary (citable) accession number: Q68FB1 Secondary accession number(s): Q28H68 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 22, 2005 |
Last sequence update: | October 11, 2004 | |
Last modified: | October 7, 2020 | |
This is version 89 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families