UniProtKB - Q68F70 (INT4_XENLA)
Protein
Integrator complex subunit 4
Gene
ints4
Organism
Xenopus laevis (African clawed frog)
Status
Functioni
Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.By similarity
Names & Taxonomyi
Protein namesi | Recommended name: Integrator complex subunit 4Short name: Int4 |
Gene namesi | Name:ints4 |
Organismi | Xenopus laevis (African clawed frog) |
Taxonomic identifieri | 8355 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Amphibia › Batrachia › Anura › Pipoidea › Pipidae › Xenopodinae › Xenopus › Xenopus |
Organism-specific databases
Xenbasei | XB-GENE-5841134, ints4.L |
Subcellular locationi
Keywords - Cellular componenti
NucleusPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000259540 | 1 – 969 | Integrator complex subunit 4Add BLAST | 969 |
Proteomic databases
MaxQBi | Q68F70 |
Interactioni
Subunit structurei
Belongs to the multiprotein complex Integrator.
By similarityFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 68 – 107 | HEAT 1Add BLAST | 40 | |
Repeati | 147 – 185 | HEAT 2Add BLAST | 39 | |
Repeati | 192 – 230 | HEAT 3Add BLAST | 39 | |
Repeati | 231 – 265 | HEAT 4Add BLAST | 35 | |
Repeati | 279 – 315 | HEAT 5Add BLAST | 37 | |
Repeati | 371 – 407 | HEAT 6Add BLAST | 37 | |
Repeati | 408 – 446 | HEAT 7Add BLAST | 39 | |
Repeati | 448 – 486 | HEAT 8Add BLAST | 39 |
Sequence similaritiesi
Belongs to the Integrator subunit 4 family.Curated
Keywords - Domaini
RepeatPhylogenomic databases
OrthoDBi | 256550at2759 |
Family and domain databases
Gene3Di | 1.25.10.10, 2 hits |
InterProi | View protein in InterPro IPR011989, ARM-like IPR016024, ARM-type_fold |
SUPFAMi | SSF48371, SSF48371, 1 hit |
i Sequence
Sequence statusi: Complete.
Q68F70-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAAHLKKRVY EEFTRVVQQQ PLEEPSAKKL RLTKPSKSAA LHIDLCKATS
60 70 80 90 100
PADALQYLLQ FARKPVEAES VEGVVRILLE HYYKENDTSV RLKIASLLGL
110 120 130 140 150
LSKTAGFCPD SIVDDVINTL QNEKSHQVLA QLLDTLLEIG LKLLDIVSHR
160 170 180 190 200
MRLVDVACKH LSDTSHGVRN KCLQLLGCLG SVEASPAKEV ENAVAKDVQK
210 220 230 240 250
IIGDYFIDQD PRVRTAAIKA MLQLHERGLK LQQAMYNQAC KLLTDDYEQV
260 270 280 290 300
RSAAVELSWV LSQLYSESIV PIPSSNEEIR LVDDAFGKVC HMVSDGSWVV
310 320 330 340 350
RVQACKLLGS MLQVSPHFLE QTLDKKLMSD LRRKRTAHER AKELYSSGEF
360 370 380 390 400
SSGRKWGDDA PKEELDTGAV NLIDSGACGA FVHGLEDEMY EVRIAAVESL
410 420 430 440 450
CLLARSSAPF AEKCLDFLVD MFNDEIEEVR LQSIHTMRKI SDNITLREDQ
460 470 480 490 500
LDTVLAVLED KSRDIREALH ELLCCTNVST KECIQLALVE LLKNLSKYPT
510 520 530 540 550
DRESIWKCLK FLGSRHPTLV LSLVPELLST HPFFDTPEPD MDDPAYIAVL
560 570 580 590 600
VLIFNAAKCC PTMPALFSDH TFRHYTYLRD SLSHLVPALN LPSVRWSWIP
610 620 630 640 650
DVITEAPPED PSQQFLQLSL ERVHNLQHLG SQGTQELLEF TIRDLQRIGE
660 670 680 690 700
LQSDLAGMAD FSATYLRCHL LLTKALNEKL WNLAAPLFLK NSLTTNAVKQ
710 720 730 740 750
ILEETYKMEF MYSGLETRQV AIIHHMRLQA KALQLLVTAR TTKGAEPLFG
760 770 780 790 800
MCEEFLQEVD FFQRCFISEL PHMQDSFVDK LLDLVPRLVN SKPLEMVKIL
810 820 830 840 850
QTTLRQCTFL RLTLPEQIHR ASSHIIEPAE ESDNPIRFTS GLVVALDVDA
860 870 880 890 900
TLEHVQEPQS TVKVQVVYPD GQVQIIHPKP ADFRNPGPGR HRLITQVYLS
910 920 930 940 950
HTAWTEPCQI EVRLLLAYSS SRSKVMSRAS NSTWGESTET VPSTESSTEG
960
TIPFSKPVKV FLMPKPARR
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC079973 mRNA Translation: AAH79973.1 |
RefSeqi | NP_001087469.1, NM_001094000.1 |
Genome annotation databases
GeneIDi | 447293 |
KEGGi | xla:447293 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC079973 mRNA Translation: AAH79973.1 |
RefSeqi | NP_001087469.1, NM_001094000.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
MaxQBi | Q68F70 |
Genome annotation databases
GeneIDi | 447293 |
KEGGi | xla:447293 |
Organism-specific databases
CTDi | 447293 |
Xenbasei | XB-GENE-5841134, ints4.L |
Phylogenomic databases
OrthoDBi | 256550at2759 |
Family and domain databases
Gene3Di | 1.25.10.10, 2 hits |
InterProi | View protein in InterPro IPR011989, ARM-like IPR016024, ARM-type_fold |
SUPFAMi | SSF48371, SSF48371, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | INT4_XENLA | |
Accessioni | Q68F70Primary (citable) accession number: Q68F70 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 31, 2006 |
Last sequence update: | October 11, 2004 | |
Last modified: | December 2, 2020 | |
This is version 65 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |