Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Uncharacterized protein KIAA0895-like

Gene

KIAA0895L

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein KIAA0895-like
Gene namesi
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 16

Organism-specific databases

EuPathDBiHostDB:ENSG00000196123.12
HGNCiHGNC:34408 KIAA0895L
neXtProtiNX_Q68EN5

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000196123
PharmGKBiPA164721818

Polymorphism and mutation databases

BioMutaiKIAA0895L
DMDMi74736337

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003206191 – 471Uncharacterized protein KIAA0895-likeAdd BLAST471

Proteomic databases

PaxDbiQ68EN5
PeptideAtlasiQ68EN5
PRIDEiQ68EN5
ProteomicsDBi66136
66137 [Q68EN5-2]
66138 [Q68EN5-3]

PTM databases

iPTMnetiQ68EN5
PhosphoSitePlusiQ68EN5

Expressioni

Gene expression databases

BgeeiENSG00000196123 Expressed in 139 organ(s), highest expression level in right hemisphere of cerebellum
ExpressionAtlasiQ68EN5 baseline and differential
GenevisibleiQ68EN5 HS

Organism-specific databases

HPAiHPA065996

Interactioni

Protein-protein interaction databases

BioGridi575692, 1 interactor
IntActiQ68EN5, 1 interactor

Structurei

3D structure databases

ProteinModelPortaliQ68EN5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi14 – 65Pro-richAdd BLAST52

Phylogenomic databases

eggNOGiENOG410IGSS Eukaryota
ENOG410YKC2 LUCA
GeneTreeiENSGT00390000004417
HOGENOMiHOG000069902
HOVERGENiHBG067127
InParanoidiQ68EN5
OMAiHQAVGII
OrthoDBiEOG091G0669
PhylomeDBiQ68EN5
TreeFamiTF329621

Family and domain databases

InterProiView protein in InterPro
IPR012548 DUF1704
PANTHERiPTHR31817 PTHR31817, 1 hit
PfamiView protein in Pfam
PF08014 DUF1704, 1 hit
SMARTiView protein in SMART
SM01154 DUF1704, 1 hit

Sequences (3+)i

Sequence statusi: Complete.

This entry describes 3 isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q68EN5-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MVLDSGAQAY DQAPPSPPTS PPSLRHRLKP SDRDGPPLYP WSQSLALPLA
60 70 80 90 100
LAVPPALQPQ PEQQPFSQML LGHRGHMRRS ESTYSVNSTG RRGRGTLGRP
110 120 130 140 150
PPGRGRNPGG GTLRPAASLP HIAKTQRDAG HIASKSPCML VALRPTNMDR
160 170 180 190 200
ERDKFFQSHY TYNPQFEYQE PMPTAVLEKY CEASGQFIHQ AVGIIEAVLE
210 220 230 240 250
KFGTYEHFEA ATGGQLLTKC QIWSIVRKYM QKEGCAGEVV VQLSEDLLSQ
260 270 280 290 300
AVMMVENSRP TLAINLTGAR QYWLEGMLRH EIGTHYLRGV NNARQPWHNA
310 320 330 340 350
EGRLRYGLRP ANPTEEGLAS LHSVLFRKQP FLWRAALLYY TIHRAARMSF
360 370 380 390 400
RQLFQDLERY VQDADVRWEY CVRAKRGQTD TSLPGCFSKD QVYLDGIVRI
410 420 430 440 450
LRHRQTIDFP LLTSLGKVSY EDVDHLRPHG VLDNTRVPHF MQDLARYRQQ
460 470
LEHIMATNRL DEAELGRLLP D
Length:471
Mass (Da):53,446
Last modified:October 11, 2004 - v1
Checksum:iC60BC58B867DB156
GO
Isoform 2 (identifier: Q68EN5-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     385-408: GCFSKDQVYLDGIVRILRHRQTID → ARTRCTWTASCAFCDIARPSISRC
     409-471: Missing.

Show »
Length:408
Mass (Da):45,967
Checksum:i8DFC1AEFE101E564
GO
Isoform 3 (identifier: Q68EN5-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-282: MVLDSGAQAY...WLEGMLRHEI → MTVQDDMGTQ...PAPPPLAFPA

Show »
Length:316
Mass (Da):35,387
Checksum:i08D8C5F25039BE45
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
I3L230I3L230_HUMAN
Uncharacterized protein KIAA0895-li...
KIAA0895L
205Annotation score:

Sequence cautioni

The sequence AAI28540 differs from that shown. Reason: Erroneous initiation.Curated
The sequence CAD38862 differs from that shown. Reason: Erroneous translation. Erroneous translation incorporating non-existent frameshift.Curated

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0316891 – 282MVLDS…LRHEI → MTVQDDMGTQDVGQGGICIL VPRRAGGNVSLGEFVHVCGC VGVGWGADGWERIHVCEPLW ILGCESTGGGASRCLGLGEP VCEPEFRSMRMEVSRPEPRP DGTGPGLGSQAGPRTPRPAP PPLAFPA in isoform 3. 1 PublicationAdd BLAST282
Alternative sequenceiVSP_031690385 – 408GCFSK…RQTID → ARTRCTWTASCAFCDIARPS ISRC in isoform 2. 1 PublicationAdd BLAST24
Alternative sequenceiVSP_031691409 – 471Missing in isoform 2. 1 PublicationAdd BLAST63

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK092303 mRNA Translation: BAC03856.1
AL834156 mRNA Translation: CAD38862.1 Sequence problems.
CH471092 Genomic DNA Translation: EAW83091.1
BC007594 mRNA Translation: AAH07594.1
BC080183 mRNA Translation: AAH80183.1
BC128539 mRNA Translation: AAI28540.1 Different initiation.
CCDSiCCDS42177.1 [Q68EN5-1]
RefSeqiNP_001035805.1, NM_001040715.1 [Q68EN5-1]
UniGeneiHs.651201

Genome annotation databases

EnsembliENST00000290881; ENSP00000290881; ENSG00000196123 [Q68EN5-1]
ENST00000561621; ENSP00000457099; ENSG00000196123 [Q68EN5-2]
ENST00000563902; ENSP00000456838; ENSG00000196123 [Q68EN5-1]
GeneIDi653319
KEGGihsa:653319
UCSCiuc002ert.4 human [Q68EN5-1]

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK092303 mRNA Translation: BAC03856.1
AL834156 mRNA Translation: CAD38862.1 Sequence problems.
CH471092 Genomic DNA Translation: EAW83091.1
BC007594 mRNA Translation: AAH07594.1
BC080183 mRNA Translation: AAH80183.1
BC128539 mRNA Translation: AAI28540.1 Different initiation.
CCDSiCCDS42177.1 [Q68EN5-1]
RefSeqiNP_001035805.1, NM_001040715.1 [Q68EN5-1]
UniGeneiHs.651201

3D structure databases

ProteinModelPortaliQ68EN5
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi575692, 1 interactor
IntActiQ68EN5, 1 interactor

PTM databases

iPTMnetiQ68EN5
PhosphoSitePlusiQ68EN5

Polymorphism and mutation databases

BioMutaiKIAA0895L
DMDMi74736337

Proteomic databases

PaxDbiQ68EN5
PeptideAtlasiQ68EN5
PRIDEiQ68EN5
ProteomicsDBi66136
66137 [Q68EN5-2]
66138 [Q68EN5-3]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000290881; ENSP00000290881; ENSG00000196123 [Q68EN5-1]
ENST00000561621; ENSP00000457099; ENSG00000196123 [Q68EN5-2]
ENST00000563902; ENSP00000456838; ENSG00000196123 [Q68EN5-1]
GeneIDi653319
KEGGihsa:653319
UCSCiuc002ert.4 human [Q68EN5-1]

Organism-specific databases

CTDi653319
EuPathDBiHostDB:ENSG00000196123.12
GeneCardsiKIAA0895L
HGNCiHGNC:34408 KIAA0895L
HPAiHPA065996
neXtProtiNX_Q68EN5
OpenTargetsiENSG00000196123
PharmGKBiPA164721818
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IGSS Eukaryota
ENOG410YKC2 LUCA
GeneTreeiENSGT00390000004417
HOGENOMiHOG000069902
HOVERGENiHBG067127
InParanoidiQ68EN5
OMAiHQAVGII
OrthoDBiEOG091G0669
PhylomeDBiQ68EN5
TreeFamiTF329621

Miscellaneous databases

ChiTaRSiKIAA0895L human
GeneWikiiKIAA0895L
GenomeRNAii653319
PROiPR:Q68EN5

Gene expression databases

BgeeiENSG00000196123 Expressed in 139 organ(s), highest expression level in right hemisphere of cerebellum
ExpressionAtlasiQ68EN5 baseline and differential
GenevisibleiQ68EN5 HS

Family and domain databases

InterProiView protein in InterPro
IPR012548 DUF1704
PANTHERiPTHR31817 PTHR31817, 1 hit
PfamiView protein in Pfam
PF08014 DUF1704, 1 hit
SMARTiView protein in SMART
SM01154 DUF1704, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiK895L_HUMAN
AccessioniPrimary (citable) accession number: Q68EN5
Secondary accession number(s): A2VCS8
, Q8N3H9, Q8NAQ5, Q96IE5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: October 11, 2004
Last modified: November 7, 2018
This is version 106 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 16
    Human chromosome 16: entries, gene names and cross-references to MIM
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again