UniProtKB - Q68D42 (TM215_HUMAN)
Protein
Transmembrane protein 215
Gene
TMEM215
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Recommended name: Transmembrane protein 215 |
Gene namesi | Name:TMEM215 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:33816, TMEM215 |
neXtProti | NX_Q68D42 |
VEuPathDBi | HostDB:ENSG00000188133.5 |
Subcellular locationi
Other locations
- Membrane Curated; Multi-pass membrane protein Curated
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 12 – 32 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 40 – 60 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
MembranePathology & Biotechi
Organism-specific databases
DisGeNETi | 401498 |
OpenTargetsi | ENSG00000188133 |
PharmGKBi | PA162406544 |
Miscellaneous databases
Pharosi | Q68D42, Tdark |
Genetic variation databases
BioMutai | TMEM215 |
DMDMi | 74748275 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000319324 | 1 – 235 | Transmembrane protein 215Add BLAST | 235 |
Proteomic databases
MassIVEi | Q68D42 |
PaxDbi | Q68D42 |
PeptideAtlasi | Q68D42 |
PRIDEi | Q68D42 |
ProteomicsDBi | 66049 |
PTM databases
iPTMneti | Q68D42 |
PhosphoSitePlusi | Q68D42 |
Expressioni
Gene expression databases
Bgeei | ENSG00000188133, Expressed in tibial nerve and 40 other tissues |
Organism-specific databases
HPAi | ENSG00000188133, Tissue enhanced (endometrium, retina, testis) |
Interactioni
Protein-protein interaction databases
STRINGi | 9606.ENSP00000345468 |
Miscellaneous databases
RNActi | Q68D42, protein |
Family & Domainsi
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | ENOG502QZ55, Eukaryota |
GeneTreei | ENSGT00390000006684 |
HOGENOMi | CLU_1165487_0_0_1 |
InParanoidi | Q68D42 |
OMAi | CCYINQS |
OrthoDBi | 1440273at2759 |
PhylomeDBi | Q68D42 |
TreeFami | TF335695 |
Family and domain databases
InterProi | View protein in InterPro IPR031486, TMEM215 |
PANTHERi | PTHR31922, PTHR31922, 1 hit |
Pfami | View protein in Pfam PF15746, TMEM215, 1 hit |
i Sequence
Sequence statusi: Complete.
Q68D42-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MRPDDINPRT GLVVALVSVF LVFGFMFTVS GMKGETLGNI PLLAIGPAIC
60 70 80 90 100
LPGIAAIALA RKTEGCTKWP ENELLWVRKL PCFRKPKDKE VVELLRTPSD
110 120 130 140 150
LESGKGSSDE LAKKAGLRGK PPPQSQGEVS VASSINSPTP TEEGECQSLV
160 170 180 190 200
QNGHQEETSR YLDGYCPSGS SLTYSALDVK CSARDRSECP EPEDSIFFVP
210 220 230
QDSIIVCSYK QNSPYDRYCC YINQIQGRWD HETIV
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 69 | W → R in BAC86126 (PubMed:14702039).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK125320 mRNA Translation: BAC86126.1 BX647550 mRNA Translation: CAH56136.1 CR749589 mRNA Translation: CAH18388.1 CH471071 Genomic DNA Translation: EAW58539.1 |
CCDSi | CCDS6530.1 |
RefSeqi | NP_997723.2, NM_212558.2 |
Genome annotation databases
Ensembli | ENST00000342743; ENSP00000345468; ENSG00000188133 |
GeneIDi | 401498 |
KEGGi | hsa:401498 |
UCSCi | uc003zri.5, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK125320 mRNA Translation: BAC86126.1 BX647550 mRNA Translation: CAH56136.1 CR749589 mRNA Translation: CAH18388.1 CH471071 Genomic DNA Translation: EAW58539.1 |
CCDSi | CCDS6530.1 |
RefSeqi | NP_997723.2, NM_212558.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 9606.ENSP00000345468 |
PTM databases
iPTMneti | Q68D42 |
PhosphoSitePlusi | Q68D42 |
Genetic variation databases
BioMutai | TMEM215 |
DMDMi | 74748275 |
Proteomic databases
MassIVEi | Q68D42 |
PaxDbi | Q68D42 |
PeptideAtlasi | Q68D42 |
PRIDEi | Q68D42 |
ProteomicsDBi | 66049 |
Protocols and materials databases
Antibodypediai | 63219, 26 antibodies |
Genome annotation databases
Ensembli | ENST00000342743; ENSP00000345468; ENSG00000188133 |
GeneIDi | 401498 |
KEGGi | hsa:401498 |
UCSCi | uc003zri.5, human |
Organism-specific databases
CTDi | 401498 |
DisGeNETi | 401498 |
GeneCardsi | TMEM215 |
HGNCi | HGNC:33816, TMEM215 |
HPAi | ENSG00000188133, Tissue enhanced (endometrium, retina, testis) |
neXtProti | NX_Q68D42 |
OpenTargetsi | ENSG00000188133 |
PharmGKBi | PA162406544 |
VEuPathDBi | HostDB:ENSG00000188133.5 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | ENOG502QZ55, Eukaryota |
GeneTreei | ENSGT00390000006684 |
HOGENOMi | CLU_1165487_0_0_1 |
InParanoidi | Q68D42 |
OMAi | CCYINQS |
OrthoDBi | 1440273at2759 |
PhylomeDBi | Q68D42 |
TreeFami | TF335695 |
Enzyme and pathway databases
PathwayCommonsi | Q68D42 |
Miscellaneous databases
BioGRID-ORCSi | 401498, 2 hits in 868 CRISPR screens |
GenomeRNAii | 401498 |
Pharosi | Q68D42, Tdark |
PROi | PR:Q68D42 |
RNActi | Q68D42, protein |
Gene expression databases
Bgeei | ENSG00000188133, Expressed in tibial nerve and 40 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR031486, TMEM215 |
PANTHERi | PTHR31922, PTHR31922, 1 hit |
Pfami | View protein in Pfam PF15746, TMEM215, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | TM215_HUMAN | |
Accessioni | Q68D42Primary (citable) accession number: Q68D42 Secondary accession number(s): Q6ZUU2 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 26, 2008 |
Last sequence update: | October 11, 2004 | |
Last modified: | February 10, 2021 | |
This is version 99 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Human chromosome 9
Human chromosome 9: entries, gene names and cross-references to MIM