Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 125 (02 Jun 2021)
Sequence version 2 (29 May 2007)
Previous versions | rss
Add a publicationFeedback
Protein

Glycosyltransferase 8 domain-containing protein 1

Gene

GLT8D1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGlycosyltransferase, Transferase

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q68CQ7

Protein family/group databases

Carbohydrate-Active enZymes

More...
CAZyi
GT8, Glycosyltransferase Family 8

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Glycosyltransferase 8 domain-containing protein 1 (EC:2.4.1.-)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:GLT8D1
Synonyms:GALA4A
ORF Names:AD-017, MSTP137, UNQ572/PRO1134
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:24870, GLT8D1

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
618399, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q68CQ7

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000016864.16

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 7CytoplasmicSequence analysis7
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei8 – 28Helical; Signal-anchor for type II membrane proteinSequence analysisAdd BLAST21
Topological domaini29 – 371LumenalSequence analysisAdd BLAST343

Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
55830

MalaCards human disease database

More...
MalaCardsi
GLT8D1

Open Targets

More...
OpenTargetsi
ENSG00000016864

Orphanet; a database dedicated to information on rare diseases and orphan drugs

More...
Orphaneti
803, Amyotrophic lateral sclerosis

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134947079

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q68CQ7, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
GLT8D1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
152125896

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002885281 – 371Glycosyltransferase 8 domain-containing protein 1Add BLAST371

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi249N-linked (GlcNAc...) asparagine1 Publication1
Glycosylationi257N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q68CQ7

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q68CQ7

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q68CQ7

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q68CQ7

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q68CQ7

PeptideAtlas

More...
PeptideAtlasi
Q68CQ7

PRoteomics IDEntifications database

More...
PRIDEi
Q68CQ7

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
66021 [Q68CQ7-1]
66022 [Q68CQ7-2]

PTM databases

GlyConnect protein glycosylation platform

More...
GlyConnecti
1277, 1 N-Linked glycan (1 site)

GlyGen: Computational and Informatics Resources for Glycoscience

More...
GlyGeni
Q68CQ7, 4 sites

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q68CQ7

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q68CQ7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000016864, Expressed in pituitary gland and 239 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q68CQ7, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q68CQ7, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000016864, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
120935, 13 interactors

Protein interaction database and analysis system

More...
IntActi
Q68CQ7, 12 interactors

Molecular INTeraction database

More...
MINTi
Q68CQ7

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000266014

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q68CQ7, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q68CQ7

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the glycosyltransferase 8 family.Curated

Keywords - Domaini

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QTN8, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000159273

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_010770_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q68CQ7

Identification of Orthologs from Complete Genome Data

More...
OMAi
ADVWEKW

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q68CQ7

TreeFam database of animal gene trees

More...
TreeFami
TF332433

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.90.550.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002495, Glyco_trans_8
IPR029044, Nucleotide-diphossugar_trans

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01501, Glyco_transf_8, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53448, SSF53448, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 6 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q68CQ7-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSFRKVNIII LVLAVALFLL VLHHNFLSLS SLLRNEVTDS GIVGPQPIDF
60 70 80 90 100
VPNALRHAVD GRQEEIPVVI AASEDRLGGA IAAINSIQHN TRSNVIFYIV
110 120 130 140 150
TLNNTADHLR SWLNSDSLKS IRYKIVNFDP KLLEGKVKED PDQGESMKPL
160 170 180 190 200
TFARFYLPIL VPSAKKAIYM DDDVIVQGDI LALYNTALKP GHAAAFSEDC
210 220 230 240 250
DSASTKVVIR GAGNQYNYIG YLDYKKERIR KLSMKASTCS FNPGVFVANL
260 270 280 290 300
TEWKRQNITN QLEKWMKLNV EEGLYSRTLA GSITTPPLLI VFYQQHSTID
310 320 330 340 350
PMWNVRHLGS SAGKRYSPQF VKAAKLLHWN GHLKPWGRTA SYTDVWEKWY
360 370
IPDPTGKFNL IRRYTEISNI K
Length:371
Mass (Da):41,935
Last modified:May 29, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i43492FB4E678F3D0
GO
Isoform 2 (identifier: Q68CQ7-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     216-259: YNYIGYLDYK...LTEWKRQNIT → VNCLPNTPLP...FIPNLKPAFL
     260-371: Missing.

Show »
Length:259
Mass (Da):28,544
Checksum:iEF8FB0768DA499AC
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
C9J6X9C9J6X9_HUMAN
Glycosyltransferase 8 domain-contai...
GLT8D1
30Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9J880C9J880_HUMAN
Glycosyltransferase 8 domain-contai...
GLT8D1
174Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JNB0C9JNB0_HUMAN
Glycosyltransferase 8 domain-contai...
GLT8D1
62Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JPK4C9JPK4_HUMAN
Glycosyltransferase 8 domain-contai...
GLT8D1
89Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JY96C9JY96_HUMAN
Glycosyltransferase 8 domain-contai...
GLT8D1
63Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H7C4V6H7C4V6_HUMAN
Glycosyltransferase 8 domain-contai...
GLT8D1
23Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAQ13652 differs from that shown. Reason: Frameshift.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti50F → C in AAQ13652 (Ref. 7) Curated1
Sequence conflicti201D → G in CAH18681 (PubMed:17974005).Curated1
Sequence conflicti301P → L in AAQ13652 (Ref. 7) Curated1
Sequence conflicti349W → G in AAQ13652 (Ref. 7) Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_032443210R → H1 PublicationCorresponds to variant dbSNP:rs2276812Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_025705216 – 259YNYIG…RQNIT → VNCLPNTPLPTILFNGKRLQ IQGTLLLQFTLPNHFIPNLK PAFL in isoform 2. 1 PublicationAdd BLAST44
Alternative sequenceiVSP_025706260 – 371Missing in isoform 2. 1 PublicationAdd BLAST112

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AJ271710 mRNA Translation: CAC19666.1
AF157318 mRNA Translation: AAF67484.1
AY358579 mRNA Translation: AAQ88942.1
AK027517 mRNA Translation: BAB55170.1
AK075031 mRNA Translation: BAC11363.1
CR749821 mRNA Translation: CAH18681.1
BC119670 mRNA Translation: AAI19671.1
BC119671 mRNA Translation: AAI19672.1
AF175227 mRNA Translation: AAQ13652.1 Frameshift.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS2862.1 [Q68CQ7-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001010983.1, NM_001010983.2 [Q68CQ7-1]
NP_001265209.1, NM_001278280.1 [Q68CQ7-1]
NP_001265210.1, NM_001278281.1 [Q68CQ7-1]
NP_060916.1, NM_018446.3 [Q68CQ7-1]
NP_690909.1, NM_152932.2 [Q68CQ7-1]
XP_016862346.1, XM_017006857.1
XP_016862347.1, XM_017006858.1
XP_016862348.1, XM_017006859.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000266014; ENSP00000266014; ENSG00000016864 [Q68CQ7-1]
ENST00000394783; ENSP00000378263; ENSG00000016864 [Q68CQ7-1]
ENST00000478968; ENSP00000419612; ENSG00000016864 [Q68CQ7-1]
ENST00000491606; ENSP00000418853; ENSG00000016864 [Q68CQ7-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
55830

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:55830

UCSC genome browser

More...
UCSCi
uc003dfi.6, human [Q68CQ7-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ271710 mRNA Translation: CAC19666.1
AF157318 mRNA Translation: AAF67484.1
AY358579 mRNA Translation: AAQ88942.1
AK027517 mRNA Translation: BAB55170.1
AK075031 mRNA Translation: BAC11363.1
CR749821 mRNA Translation: CAH18681.1
BC119670 mRNA Translation: AAI19671.1
BC119671 mRNA Translation: AAI19672.1
AF175227 mRNA Translation: AAQ13652.1 Frameshift.
CCDSiCCDS2862.1 [Q68CQ7-1]
RefSeqiNP_001010983.1, NM_001010983.2 [Q68CQ7-1]
NP_001265209.1, NM_001278280.1 [Q68CQ7-1]
NP_001265210.1, NM_001278281.1 [Q68CQ7-1]
NP_060916.1, NM_018446.3 [Q68CQ7-1]
NP_690909.1, NM_152932.2 [Q68CQ7-1]
XP_016862346.1, XM_017006857.1
XP_016862347.1, XM_017006858.1
XP_016862348.1, XM_017006859.1

3D structure databases

SMRiQ68CQ7
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi120935, 13 interactors
IntActiQ68CQ7, 12 interactors
MINTiQ68CQ7
STRINGi9606.ENSP00000266014

Protein family/group databases

CAZyiGT8, Glycosyltransferase Family 8

PTM databases

GlyConnecti1277, 1 N-Linked glycan (1 site)
GlyGeniQ68CQ7, 4 sites
iPTMnetiQ68CQ7
PhosphoSitePlusiQ68CQ7

Genetic variation databases

BioMutaiGLT8D1
DMDMi152125896

Proteomic databases

EPDiQ68CQ7
jPOSTiQ68CQ7
MassIVEiQ68CQ7
MaxQBiQ68CQ7
PaxDbiQ68CQ7
PeptideAtlasiQ68CQ7
PRIDEiQ68CQ7
ProteomicsDBi66021 [Q68CQ7-1]
66022 [Q68CQ7-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
2243, 158 antibodies

The DNASU plasmid repository

More...
DNASUi
55830

Genome annotation databases

EnsembliENST00000266014; ENSP00000266014; ENSG00000016864 [Q68CQ7-1]
ENST00000394783; ENSP00000378263; ENSG00000016864 [Q68CQ7-1]
ENST00000478968; ENSP00000419612; ENSG00000016864 [Q68CQ7-1]
ENST00000491606; ENSP00000418853; ENSG00000016864 [Q68CQ7-1]
GeneIDi55830
KEGGihsa:55830
UCSCiuc003dfi.6, human [Q68CQ7-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
55830
DisGeNETi55830

GeneCards: human genes, protein and diseases

More...
GeneCardsi
GLT8D1
HGNCiHGNC:24870, GLT8D1
HPAiENSG00000016864, Low tissue specificity
MalaCardsiGLT8D1
MIMi618399, gene
neXtProtiNX_Q68CQ7
OpenTargetsiENSG00000016864
Orphaneti803, Amyotrophic lateral sclerosis
PharmGKBiPA134947079
VEuPathDBiHostDB:ENSG00000016864.16

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG502QTN8, Eukaryota
GeneTreeiENSGT00940000159273
HOGENOMiCLU_010770_0_0_1
InParanoidiQ68CQ7
OMAiADVWEKW
PhylomeDBiQ68CQ7
TreeFamiTF332433

Enzyme and pathway databases

PathwayCommonsiQ68CQ7

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
55830, 11 hits in 994 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
GLT8D1, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
55830
PharosiQ68CQ7, Tbio

Protein Ontology

More...
PROi
PR:Q68CQ7
RNActiQ68CQ7, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000016864, Expressed in pituitary gland and 239 other tissues
ExpressionAtlasiQ68CQ7, baseline and differential
GenevisibleiQ68CQ7, HS

Family and domain databases

Gene3Di3.90.550.10, 1 hit
InterProiView protein in InterPro
IPR002495, Glyco_trans_8
IPR029044, Nucleotide-diphossugar_trans
PfamiView protein in Pfam
PF01501, Glyco_transf_8, 1 hit
SUPFAMiSSF53448, SSF53448, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiGL8D1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q68CQ7
Secondary accession number(s): Q7Z4D1, Q8N2J6, Q9P0I5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: May 29, 2007
Last modified: June 2, 2021
This is version 125 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again