TPGS2

Functionⁱ

Enzyme and pathway databases

Reactomeⁱ	R-HSA-8955332 Carboxyterminal post-translational modifications of tubulin

Reactomeⁱ

R-HSA-8955332 Carboxyterminal post-translational modifications of tubulin

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Tubulin polyglutamylase complex subunit 2 Short name: PGs2
Gene namesⁱ	Name:TPGS2 Synonyms:C18orf10 ORF Names:HMFN0601, L17
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 18

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000134779.14
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:24561 TPGS2
neXtProtⁱ	NX_Q68CL5

Keywords - Cellular componentⁱ

Cytoplasm, Cytoskeleton, Microtubule

Pathology & Biotechⁱ

Organism-specific databases

DisGeNET More...DisGeNETⁱ	25941
Open Targets More...OpenTargetsⁱ	ENSG00000134779
PharmGKBⁱ	PA128394637

Polymorphism and mutation databases

DMDMⁱ	114152891

DMDMⁱ

114152891

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000079304	1 – 300	Tubulin polyglutamylase complex subunit 2Add BLAST		300

Proteomic databases

EPDⁱ	Q68CL5
PaxDbⁱ	Q68CL5
PeptideAtlas More...PeptideAtlasⁱ	Q68CL5
PRIDEⁱ	Q68CL5
ProteomicsDBⁱ	66006 66007 [Q68CL5-1] 66008 [Q68CL5-3]

PTM databases

iPTMnetⁱ	Q68CL5
PhosphoSitePlusⁱ	Q68CL5

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000134779
CleanExⁱ	HS_C18orf10
ExpressionAtlasⁱ	Q68CL5 baseline and differential
Genevisibleⁱ	Q68CL5 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA040596 HPA040617 HPA061753

HPAⁱ

HPA040596
HPA040617
HPA061753

Interactionⁱ

Subunit structureⁱ

Part of the neuronal tubulin polyglutamylase complex which contains TPGS1, TPGS2, TTLL1, LRRC49 and NICN1.By similarity

Protein-protein interaction databases

BioGridⁱ	117438, 13 interactors
IntActⁱ	Q68CL5, 3 interactors
STRINGⁱ	9606.ENSP00000335144

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q68CL5
SMRⁱ	Q68CL5
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Phylogenomic databases

eggNOGⁱ	ENOG410IJVC Eukaryota ENOG4111HTQ LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000018344
HOGENOMⁱ	HOG000294114
HOVERGENⁱ	HBG073636
InParanoidⁱ	Q68CL5
KEGG Orthology (KO) More...KOⁱ	K16605
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0MZO
PhylomeDBⁱ	Q68CL5
TreeFamⁱ	TF325540

Family and domain databases

InterProⁱ	View protein in InterPro IPR018958 Knr4/Smi1-like_dom IPR039231 TPGS2
PANTHERⁱ	PTHR31854 PTHR31854, 1 hit
SMARTⁱ	View protein in SMART SM00860 SMI1_KNR4, 1 hit

Sequences (5)ⁱ

Sequence statusⁱ: Complete.

This entry describes 5 isoformsⁱ produced by alternative splicing. Align Add to basket Added to basket

Isoform 2 (identifier: Q68CL5-2) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MEEEASSPGL GCSKPHLEKL TLGITRILES SPGVTEVTII EKPPAERHMI 
        60         70         80         90        100
SSWEQKNNCV MPEDVKNFYL MTNGFHMTWS VKLDEHIIPL GSMAINSISK 
       110        120        130        140        150
LTQLTQSSMY SLPNAPTLAD LEDDTHEASD DQPEKPHFDS RSVIFELDSC 
       160        170        180        190        200
NGSGKVCLVY KSGKPALAED TEIWFLDRAL YWHFLTDTFT AYYRLLITHL 
       210        220        230        240        250
GLPQWQYAFT SYGISPQAKQ WFSMYKPITY NTNLLTEETD SFVNKLDPSK 
       260        270        280        290        300
VFKSKNKIVI PKKKGPVQPA GGQKGPSGPS GPSTSSTSKS SSGSGNPTRK

Length:300

Mass (Da):33,318

Last modified:September 5, 2006 - v2

Checksum:ⁱF3AADD55882EC1E5

GO

Isoform 1 (identifier: Q68CL5-1) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
85-127: Missing.

« Hide

        10         20         30         40         50
MEEEASSPGL GCSKPHLEKL TLGITRILES SPGVTEVTII EKPPAERHMI 
        60         70         80         90        100
SSWEQKNNCV MPEDVKNFYL MTNGFHMTWS VKLDASDDQP EKPHFDSRSV 
       110        120        130        140        150
IFELDSCNGS GKVCLVYKSG KPALAEDTEI WFLDRALYWH FLTDTFTAYY 
       160        170        180        190        200
RLLITHLGLP QWQYAFTSYG ISPQAKQWFS MYKPITYNTN LLTEETDSFV 
       210        220        230        240        250
NKLDPSKVFK SKNKIVIPKK KGPVQPAGGQ KGPSGPSGPS TSSTSKSSSG 

SGNPTRK

Show »

Length:257

Mass (Da):28,653

Checksum:ⁱ4E3780AD249BBD57

GO

Isoform 3 (identifier: Q68CL5-3) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
220-227: QWFSMYKP → VREEHLPL
228-300: Missing.

« Hide

        10         20         30         40         50
MEEEASSPGL GCSKPHLEKL TLGITRILES SPGVTEVTII EKPPAERHMI 
        60         70         80         90        100
SSWEQKNNCV MPEDVKNFYL MTNGFHMTWS VKLDEHIIPL GSMAINSISK 
       110        120        130        140        150
LTQLTQSSMY SLPNAPTLAD LEDDTHEASD DQPEKPHFDS RSVIFELDSC 
       160        170        180        190        200
NGSGKVCLVY KSGKPALAED TEIWFLDRAL YWHFLTDTFT AYYRLLITHL 
       210        220 
GLPQWQYAFT SYGISPQAKV REEHLPL

Show »

Length:227

Mass (Da):25,665

Checksum:ⁱ7021B602DBC24361

GO

Isoform 4 (identifier: Q68CL5-4) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
85-119: Missing.

« Hide

        10         20         30         40         50
MEEEASSPGL GCSKPHLEKL TLGITRILES SPGVTEVTII EKPPAERHMI 
        60         70         80         90        100
SSWEQKNNCV MPEDVKNFYL MTNGFHMTWS VKLDDLEDDT HEASDDQPEK 
       110        120        130        140        150
PHFDSRSVIF ELDSCNGSGK VCLVYKSGKP ALAEDTEIWF LDRALYWHFL 
       160        170        180        190        200
TDTFTAYYRL LITHLGLPQW QYAFTSYGIS PQAKQWFSMY KPITYNTNLL 
       210        220        230        240        250
TEETDSFVNK LDPSKVFKSK NKIVIPKKKG PVQPAGGQKG PSGPSGPSTS 
       260 
STSKSSSGSG NPTRK

Note: No experimental confirmation available.

Show »

Length:265

Mass (Da):29,607

Checksum:ⁱE10DBB66D27A01B8

GO

Isoform 5 (identifier: Q68CL5-5) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
220-300: QWFSMYKPIT...SSGSGNPTRK → ITYNIKMNRR...VLFFTVRCCF

« Hide

        10         20         30         40         50
MEEEASSPGL GCSKPHLEKL TLGITRILES SPGVTEVTII EKPPAERHMI 
        60         70         80         90        100
SSWEQKNNCV MPEDVKNFYL MTNGFHMTWS VKLDEHIIPL GSMAINSISK 
       110        120        130        140        150
LTQLTQSSMY SLPNAPTLAD LEDDTHEASD DQPEKPHFDS RSVIFELDSC 
       160        170        180        190        200
NGSGKVCLVY KSGKPALAED TEIWFLDRAL YWHFLTDTFT AYYRLLITHL 
       210        220        230        240        250
GLPQWQYAFT SYGISPQAKI TYNIKMNRRK CVHWKLAVEP LQWELRSCVS 
       260        270        280        290        300
AGMGTGHKQR VSSMKPRSCS VCSRRQSNSM GTTVSQSFLS YGKNVLFFTV 

RCCF

Note: No experimental confirmation available. Gene prediction based on EST data.

Show »

Length:304

Mass (Da):34,399

Checksum:ⁱ5D2E6312F59D33CF

GO

Sequence cautionⁱ

The sequence AAH22199 differs from that shown. Reason: Erroneous initiation.Curated

The sequence CAB43322 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	44	P → S in CAB43322 (PubMed:17974005).Curated		1

Natural variant

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Natural variantⁱVAR_027410	47	R → C. Corresponds to variant dbSNP:rs2303507Ensembl.		1

Alternative sequence

Feature key	Position(s)	DescriptionActions	Length
Alternative sequenceⁱVSP_020113	85 – 127	Missing in isoform 1. 2 PublicationsAdd BLAST	43
Alternative sequenceⁱVSP_054525	85 – 119	Missing in isoform 4. 1 PublicationAdd BLAST	35
Alternative sequenceⁱVSP_055634	220 – 300	QWFSM…NPTRK → ITYNIKMNRRKCVHWKLAVE PLQWELRSCVSAGMGTGHKQ RVSSMKPRSCSVCSRRQSNS MGTTVSQSFLSYGKNVLFFT VRCCF in isoform 5. CuratedAdd BLAST	81
Alternative sequenceⁱVSP_014884	220 – 227	QWFSMYKP → VREEHLPL in isoform 3. 1 Publication	8
Alternative sequenceⁱVSP_014885	228 – 300	Missing in isoform 3. 1 PublicationAdd BLAST	73

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK295817 mRNA Translation: BAG58634.1 AB073382 mRNA Translation: BAD38633.1 AC009854 Genomic DNA No translation available. AC090333 Genomic DNA No translation available. BC015178 mRNA Translation: AAH15178.2 BC022199 mRNA Translation: AAH22199.2 Different initiation. BC087845 mRNA Translation: AAH87845.1 AL050225 mRNA Translation: CAB43322.2 Different initiation. AY598336 mRNA Translation: AAT06747.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS32817.1 [Q68CL5-2] CCDS62421.1 [Q68CL5-1] CCDS62422.1 [Q68CL5-4] CCDS62423.1 [Q68CL5-3] CCDS62424.1 [Q68CL5-5]
PIRⁱ	T08811
NCBI Reference Sequences More...RefSeqⁱ	NP_001258878.1, NM_001271949.1 [Q68CL5-4] NP_001258879.1, NM_001271950.1 [Q68CL5-1] NP_001258880.1, NM_001271951.1 [Q68CL5-5] NP_001258881.1, NM_001271952.1 NP_001258883.1, NM_001271954.1 [Q68CL5-3] NP_056291.2, NM_015476.3 [Q68CL5-2]
UniGeneⁱ	Hs.436636

Genome annotation databases

Ensemblⁱ	ENST00000334295; ENSP00000335144; ENSG00000134779 [Q68CL5-2] ENST00000383056; ENSP00000372530; ENSG00000134779 [Q68CL5-1] ENST00000589049; ENSP00000466973; ENSG00000134779 [Q68CL5-3] ENST00000590842; ENSP00000464780; ENSG00000134779 [Q68CL5-5] ENST00000593035; ENSP00000467392; ENSG00000134779 [Q68CL5-4]
GeneIDⁱ	25941
KEGGⁱ	hsa:25941
UCSC genome browser More...UCSCⁱ	uc002kzw.3 human [Q68CL5-2]

Keywords - Coding sequence diversityⁱ

Alternative splicing, Polymorphism

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length
Q68CL5	Chromosome 18 open reading frame 10		PANTR		300
Uncharacterized protein		PANPA		300
UPI0000D46F86		HUMAN		252
Q68CL5-1	TPGS2 isoform 11		PANTR		257
Tubulin polyglutamylase complex subunit 2 (Fragment)		HUMAN		162
TPGS2 isoform 23 (Fragment)		PONAB		163
TPGS2 isoform 13 (Fragment)		PANTR		163

Protein	Similar proteins		Species	Score	Length
Q68CL5	Chromosome 18 open reading frame 10		PANTR		300
Uncharacterized protein		PANPA		300
UPI0000D46F86		HUMAN		252
Uncharacterized protein DKFZp459I023		PONAB		317
C18orf10 (Fragment)		MACMU		153
+37
Q68CL5-1	Tubulin polyglutamylase complex subunit 2		PAPAN		257
TPGS2 isoform 10		PONAB		265
TPGS2 isoform 12		PANTR		265
UPI00020AB624		NOMLE		265
UPI00053323AF		RHIRO		265
+27
Q68CL5-3	TPGS2 isoform 14 (Fragment)		PANTR		228
UPI0005331733		RHIRO		276
UPI0005F58B55		MANLE		276
Tubulin polyglutamylase complex subunit 2		NOMLE		248
UPI000C2AA26C		Ugandan red Colobus		245
+38
Q68CL5-4	Tubulin polyglutamylase complex subunit 2		PAPAN		257
TPGS2 isoform 10		PONAB		265
TPGS2 isoform 12		PANTR		265
UPI00020AB624		NOMLE		265
UPI00053323AF		RHIRO		265
+27
Q68CL5-5	UPI0000D4C7B2		HUMAN		256
TPGS2 isoform 5		PANTR		304
Tubulin polyglutamylase complex subunit 2		MACFA		304
Uncharacterized protein		MACMU		304
Tubulin polyglutamylase complex subunit 2		CERAT		304
+20

Protein	Similar proteins		Species	Score	Length
Q68CL5	Chromosome 18 open reading frame 10		PANTR		300
Uncharacterized protein		PANPA		300
UPI0000D46F86		HUMAN		252
Uncharacterized protein DKFZp459I023		PONAB		317
C18orf10 (Fragment)		MACMU		153
+378
Q68CL5-1	Tubulin polyglutamylase complex subunit 2		NOMLE		257
UPI0005F3A3B6		MANLE		265
TPGS2 isoform 12		PANTR		265
UPI00053323AF		RHIRO		265
UPI0005F3DE18		COLAP		265
+66
Q68CL5-3	TPGS2 isoform 14 (Fragment)		PANTR		228
UPI0005F58B55		MANLE		276
UPI0005331733		RHIRO		276
Tubulin polyglutamylase complex subunit 2		NOMLE		248
Tubulin polyglutamylase complex subunit 2		RHIBE		245
+72
Q68CL5-4	Tubulin polyglutamylase complex subunit 2		NOMLE		257
UPI0005F3A3B6		MANLE		265
TPGS2 isoform 12		PANTR		265
UPI00053323AF		RHIRO		265
UPI0005F3DE18		COLAP		265
+66

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK295817 mRNA Translation: BAG58634.1 AB073382 mRNA Translation: BAD38633.1 AC009854 Genomic DNA No translation available. AC090333 Genomic DNA No translation available. BC015178 mRNA Translation: AAH15178.2 BC022199 mRNA Translation: AAH22199.2 Different initiation. BC087845 mRNA Translation: AAH87845.1 AL050225 mRNA Translation: CAB43322.2 Different initiation. AY598336 mRNA Translation: AAT06747.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS32817.1 [Q68CL5-2] CCDS62421.1 [Q68CL5-1] CCDS62422.1 [Q68CL5-4] CCDS62423.1 [Q68CL5-3] CCDS62424.1 [Q68CL5-5]
PIRⁱ	T08811
NCBI Reference Sequences More...RefSeqⁱ	NP_001258878.1, NM_001271949.1 [Q68CL5-4] NP_001258879.1, NM_001271950.1 [Q68CL5-1] NP_001258880.1, NM_001271951.1 [Q68CL5-5] NP_001258881.1, NM_001271952.1 NP_001258883.1, NM_001271954.1 [Q68CL5-3] NP_056291.2, NM_015476.3 [Q68CL5-2]
UniGeneⁱ	Hs.436636

3D structure databases

ProteinModelPortalⁱ	Q68CL5
SMRⁱ	Q68CL5
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	117438, 13 interactors
IntActⁱ	Q68CL5, 3 interactors
STRINGⁱ	9606.ENSP00000335144

PTM databases

iPTMnetⁱ	Q68CL5
PhosphoSitePlusⁱ	Q68CL5

Polymorphism and mutation databases

DMDMⁱ	114152891

DMDMⁱ

114152891

Proteomic databases

EPDⁱ	Q68CL5
PaxDbⁱ	Q68CL5
PeptideAtlas More...PeptideAtlasⁱ	Q68CL5
PRIDEⁱ	Q68CL5
ProteomicsDBⁱ	66006 66007 [Q68CL5-1] 66008 [Q68CL5-3]

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	25941
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000334295; ENSP00000335144; ENSG00000134779 [Q68CL5-2] ENST00000383056; ENSP00000372530; ENSG00000134779 [Q68CL5-1] ENST00000589049; ENSP00000466973; ENSG00000134779 [Q68CL5-3] ENST00000590842; ENSP00000464780; ENSG00000134779 [Q68CL5-5] ENST00000593035; ENSP00000467392; ENSG00000134779 [Q68CL5-4]
GeneIDⁱ	25941
KEGGⁱ	hsa:25941
UCSC genome browser More...UCSCⁱ	uc002kzw.3 human [Q68CL5-2]

Organism-specific databases

CTDⁱ	25941
DisGeNET More...DisGeNETⁱ	25941
EuPathDBⁱ	HostDB:ENSG00000134779.14
GeneCardsⁱ	TPGS2
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:24561 TPGS2
Human Protein Atlas More...HPAⁱ	HPA040596 HPA040617 HPA061753
neXtProtⁱ	NX_Q68CL5
Open Targets More...OpenTargetsⁱ	ENSG00000134779
PharmGKBⁱ	PA128394637
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	ENOG410IJVC Eukaryota ENOG4111HTQ LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000018344
HOGENOMⁱ	HOG000294114
HOVERGENⁱ	HBG073636
InParanoidⁱ	Q68CL5
KEGG Orthology (KO) More...KOⁱ	K16605
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0MZO
PhylomeDBⁱ	Q68CL5
TreeFamⁱ	TF325540

Enzyme and pathway databases

Reactomeⁱ	R-HSA-8955332 Carboxyterminal post-translational modifications of tubulin

Reactomeⁱ

R-HSA-8955332 Carboxyterminal post-translational modifications of tubulin

Miscellaneous databases

ChiTaRSⁱ	TPGS2 human
GenomeRNAiⁱ	25941
Protein Ontology More...PROⁱ	PR:Q68CL5

Gene expression databases

Bgeeⁱ	ENSG00000134779
CleanExⁱ	HS_C18orf10
ExpressionAtlasⁱ	Q68CL5 baseline and differential
Genevisibleⁱ	Q68CL5 HS

Family and domain databases

InterProⁱ	View protein in InterPro IPR018958 Knr4/Smi1-like_dom IPR039231 TPGS2
PANTHERⁱ	PTHR31854 PTHR31854, 1 hit
SMARTⁱ	View protein in SMART SM00860 SMI1_KNR4, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	TPGS2_HUMAN
Accessionⁱ	Q68CL5Primary (citable) accession number: Q68CL5 Secondary accession number(s): B4DIX2 , K7EIJ9, Q4KN59, Q8WTU3, Q96BT9, Q9Y435
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	July 19, 2005
	Last sequence update:	September 5, 2006
	Last modified:	July 18, 2018
	This is version 110 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

Human chromosome 18
Human chromosome 18: entries, gene names and cross-references to MIM
Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations

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UniProtKB - Q68CL5 (TPGS2_HUMAN)

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Tubulin polyglutamylase complex subunit 2

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Cytoskeleton

Cytoskeleton

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<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

Family and domain databases

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

Experimental Info

Natural variant

Alternative sequence

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

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Functionⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence cautionⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ