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Entry version 115 (12 Aug 2020)
Sequence version 3 (23 Mar 2010)
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Protein

Nuclear GTPase SLIP-GC

Gene

NUGGC

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Nuclear GTPase found in germinal center B-cells, where it may inhibit function of the activation-induced cytidine deaminase AICDA (PubMed:19734146). Reduces somatic hypermutation in B-cells which may enhance genome stability (By similarity).By similarity1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi107 – 114GTPSequence analysis8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase
LigandGTP-binding, Nucleotide-binding

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q68CJ6

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Nuclear GTPase SLIP-GC (EC:3.6.1.-)
Alternative name(s):
Speckled-like pattern in the germinal center
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:NUGGC
Synonyms:C8orf80
ORF Names:HMFN0672
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000189233.11

Human Gene Nomenclature Database

More...
HGNCi
HGNC:33550, NUGGC

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q68CJ6

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
389643

Open Targets

More...
OpenTargetsi
ENSG00000189233

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162380784

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q68CJ6, Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
NUGGC

Domain mapping of disease mutations (DMDM)

More...
DMDMi
292495064

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002994791 – 796Nuclear GTPase SLIP-GCAdd BLAST796

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q68CJ6

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q68CJ6

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q68CJ6

PeptideAtlas

More...
PeptideAtlasi
Q68CJ6

PRoteomics IDEntifications database

More...
PRIDEi
Q68CJ6

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
66002

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q68CJ6

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q68CJ6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in germinal center B-cell and in lymphomas derived from germinal center B-cell.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000189233, Expressed in tonsil and 80 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q68CJ6, baseline and differential

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000189233, Tissue enhanced (liver, lymphoid tissue)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000408697

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q68CJ6, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili158 – 185Sequence analysisAdd BLAST28
Coiled coili745 – 775Sequence analysisAdd BLAST31

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QVUX, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000007091

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_019456_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q68CJ6

Identification of Orthologs from Complete Genome Data

More...
OMAi
IEQCFAH

Database of Orthologous Groups

More...
OrthoDBi
455050at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q68CJ6

TreeFam database of animal gene trees

More...
TreeFami
TF352086

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR022812, Dynamin_SF
IPR027417, P-loop_NTPase

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00350, Dynamin_N, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540, SSF52540, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q68CJ6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAETKDVFGQ EPHPVEDDLY KERTRKRRKS DRDQRFRAFP SMEQSALKEY
60 70 80 90 100
EKLESRTRRV LSNTYQKLIQ SVFLDDSIPN GVKYLINRLL ALIEKPTVDP
110 120 130 140 150
IYIALFGSTG AGKSSLINAI IQQAMFLPVS GESICTSCIV QVSSGCCVQY
160 170 180 190 200
EAKIHLLSDQ EWREELKNLT KLLHRTEELS REEADAWNRD EAVEEATWKL
210 220 230 240 250
QMIYGNGAES KNYEELLRAK PKRKIPTSRV ITLKAEEAEE LSIKLDPYIR
260 270 280 290 300
TQRRDWDGEA AEMRIWPLIK HVEVTLPKSD LIPEGVVLVD IPGTGDFNSK
310 320 330 340 350
RDEMWKKTID KCSVIWVISD IERVSGGQAH EDLLNESIKA CQRGFCRDVA
360 370 380 390 400
LVVTKMDKLH LPEYLRERKA GNQAIQSQRE AVLERNEMIK LQRTRILKEK
410 420 430 440 450
LKRKLPADFK VLEASDLVYT VSAQEYWQQA LLTEEETEIP KLREYIRKSL
460 470 480 490 500
LDKKKRTVTK YVTEAFGLLL LTDSFNSTQN LPNEHLHMSV LRRFAEEKVE
510 520 530 540 550
LLEKAIAQCF ACMEQPLQEG VRTARTSYRC ILRACLVRSK GNQGFHQTLK
560 570 580 590 600
AVCLKNGIYA SRTLARIDLN EALTQPVYDQ IDPVFGSIFR TGKPTGSALM
610 620 630 640 650
PHIDAFKQSL QEKMTEIGIR SGWKYDSCKK NFLIQEISAI LGGLEDHILR
660 670 680 690 700
RKRRIYESLT ASVQSDLKLC YEEAAQITGK KACERMKDAI RRGVDRQVAE
710 720 730 740 750
GMFERAQERM QHQFQQLKTG IVEKVKGSIT TMLALASSQG DGLYKELADV
760 770 780 790
GSEYKEMEKL HRSLREVAEN ARLRKGMQEF LLRASPSKAG PPGTSL
Length:796
Mass (Da):91,132
Last modified:March 23, 2010 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iFB8EAA38B9329003
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
C9JSP2C9JSP2_HUMAN
Nuclear GTPase SLIP-GC
NUGGC
76Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAC85251 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated
The sequence BAD38652 differs from that shown. Probable cloning artifact.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_03482323R → P1 PublicationCorresponds to variant dbSNP:rs6998705Ensembl.1
Natural variantiVAR_034824180S → G. Corresponds to variant dbSNP:rs4732620Ensembl.1
Natural variantiVAR_034825328Q → R1 PublicationCorresponds to variant dbSNP:rs7817227Ensembl.1
Natural variantiVAR_034826474S → N1 PublicationCorresponds to variant dbSNP:rs13279787Ensembl.1
Natural variantiVAR_056814492R → W. Corresponds to variant dbSNP:rs2305453Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC091573 Genomic DNA No translation available.
AB075870 mRNA Translation: BAD38652.1 Sequence problems.
AK129923 mRNA Translation: BAC85251.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS47833.1

NCBI Reference Sequences

More...
RefSeqi
NP_001010906.1, NM_001010906.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000413272; ENSP00000408697; ENSG00000189233

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
389643

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:389643

UCSC genome browser

More...
UCSCi
uc003xgm.4, human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC091573 Genomic DNA No translation available.
AB075870 mRNA Translation: BAD38652.1 Sequence problems.
AK129923 mRNA Translation: BAC85251.1 Different initiation.
CCDSiCCDS47833.1
RefSeqiNP_001010906.1, NM_001010906.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi9606.ENSP00000408697

PTM databases

iPTMnetiQ68CJ6
PhosphoSitePlusiQ68CJ6

Polymorphism and mutation databases

BioMutaiNUGGC
DMDMi292495064

Proteomic databases

jPOSTiQ68CJ6
MassIVEiQ68CJ6
PaxDbiQ68CJ6
PeptideAtlasiQ68CJ6
PRIDEiQ68CJ6
ProteomicsDBi66002

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
5386, 33 antibodies

The DNASU plasmid repository

More...
DNASUi
389643

Genome annotation databases

EnsembliENST00000413272; ENSP00000408697; ENSG00000189233
GeneIDi389643
KEGGihsa:389643
UCSCiuc003xgm.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
389643
DisGeNETi389643
EuPathDBiHostDB:ENSG00000189233.11

GeneCards: human genes, protein and diseases

More...
GeneCardsi
NUGGC
HGNCiHGNC:33550, NUGGC
HPAiENSG00000189233, Tissue enhanced (liver, lymphoid tissue)
neXtProtiNX_Q68CJ6
OpenTargetsiENSG00000189233
PharmGKBiPA162380784

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG502QVUX, Eukaryota
GeneTreeiENSGT00390000007091
HOGENOMiCLU_019456_0_0_1
InParanoidiQ68CJ6
OMAiIEQCFAH
OrthoDBi455050at2759
PhylomeDBiQ68CJ6
TreeFamiTF352086

Enzyme and pathway databases

PathwayCommonsiQ68CJ6

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
389643, 7 hits in 879 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
NUGGC, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
389643
PharosiQ68CJ6, Tbio

Protein Ontology

More...
PROi
PR:Q68CJ6
RNActiQ68CJ6, protein

Gene expression databases

BgeeiENSG00000189233, Expressed in tonsil and 80 other tissues
ExpressionAtlasiQ68CJ6, baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR022812, Dynamin_SF
IPR027417, P-loop_NTPase
PfamiView protein in Pfam
PF00350, Dynamin_N, 1 hit
SUPFAMiSSF52540, SSF52540, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSLIP_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q68CJ6
Secondary accession number(s): Q6ZP73
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: March 23, 2010
Last modified: August 12, 2020
This is version 115 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. Human chromosome 8
    Human chromosome 8: entries, gene names and cross-references to MIM
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