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Entry version 114 (12 Aug 2020)
Sequence version 1 (11 Oct 2004)
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Protein

G patch domain-containing protein TGH homolog

Gene

Os06g0489200

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Functions as component of microRNA (miRNA) and small interfering RNA (siRNA) biogenesis. May assist Dicer-like (DCL) proteins to efficiently process and/or recruit the precursors of miRNAs and siRNAs.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRNA-binding
Biological processGrowth regulation, mRNA processing, RNA-mediated gene silencing

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
G patch domain-containing protein TGH homolog
Alternative name(s):
Protein TOUGH homolog
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:Os06g0489200Imported, LOC_Os06g29400Curated
ORF Names:OsJ_21406Imported, P0583E12.23Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiOryza sativa subsp. japonica (Rice)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri39947 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryzaOryza sativa
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000007752 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6
  • UP000059680 Componenti: Chromosome 6
  • UP000000763 Componenti: Chromosome 6

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004314231 – 984G patch domain-containing protein TGH homologAdd BLAST984

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q67VW6

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q67VW6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q67VW6, OS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
4530.OS06T0489200-01

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini160 – 202G-patchPROSITE-ProRule annotationAdd BLAST43
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati408 – 450SURP motifPROSITE-ProRule annotationAdd BLAST43

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili814 – 859Sequence analysisAdd BLAST46

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi857 – 984Arg/Ser-richSequence analysisAdd BLAST128

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2138, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_008613_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q67VW6

KEGG Orthology (KO)

More...
KOi
K13123

Identification of Orthologs from Complete Genome Data

More...
OMAi
PRSKMDS

Database of Orthologous Groups

More...
OrthoDBi
1175081at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.10.790, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011666, DUF1604
IPR000467, G_patch_dom
IPR040058, GPATCH1
IPR000061, Surp
IPR035967, SWAP/Surp_sf

The PANTHER Classification System

More...
PANTHERi
PTHR13384:SF19, PTHR13384:SF19, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07713, DUF1604, 1 hit
PF01805, Surp, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00648, SWAP, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF109905, SSF109905, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50174, G_PATCH, 1 hit
PS50128, SURP, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q67VW6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGFDDDDEDL VVYGTPIERE EDTSARKRRA VAEAGQLRAL PAWKQEVRDE
60 70 80 90 100
EGRRRFHGAF TGGFSAGYYN TVGTKEGWTP QTFTSSRKNR AEMKKQSIYS
110 120 130 140 150
FLDEEDIKDM GGNALETSQQ YDTFGFTATE HARKQASKEQ KERPSAIPGP
160 170 180 190 200
IPDELVVPAT TSIGVKLLMK MGWRQGRSIR DAHADSLYES RREARKAFLA
210 220 230 240 250
LSGTKTGGQK IQVDSHKSDK DDGATESFEE LHASGNTPVY VLHPKQDLHG
260 270 280 290 300
LGFDPFKHAP EFKDRKRLQK SARDRNRSDV SMRGSLLISN SGQYAPGFGI
310 320 330 340 350
GALEELGVED EDIYASGFAY EQMEVDIEPS KTASDSNYKL EDRKRGVFLA
360 370 380 390 400
FKIASSSEYK LERFDPPEIP SDFDGRHKFL TPRQDVNNLS DLAPPEVPAP
410 420 430 440 450
EDTSLRLLIE GCAAMVARCG KHIEDFYKEK SKTNTQFNFL NEGDGCSYYA
460 470 480 490 500
RKLWEYQQKY IDQQKPDTVQ SKSSDKLTAE NRGKILGERP LDRSTKSSSS
510 520 530 540 550
SFPAKEAIQL QSNLADNFVK PISLDGLPEY EKPFRNDPAK QARFEQFLKD
560 570 580 590 600
KYQGGLRPAN LIPTSTMSDV DRARERLDFE AAAETIEKGK EKKAMDPLSL
610 620 630 640 650
LGLSGINEQR FVSSTESERS IPARDEKSIY PRREEFEWRP SPILCKRFDI
660 670 680 690 700
VDPFMGKPFH VQRPRSKMDS LIFMSESTTR TNEVESSSIA PQHTSVAGAT
710 720 730 740 750
ETEAKGAATD PEIESSSVQR PVDLYKAIFS DDSDDDMAEP LANQPVDPVK
760 770 780 790 800
TSEDANMVLN RLVAEDFLES LGKELGLDVP PEKPTPPNVL FRSETPSTAN
810 820 830 840 850
AIGISRNRKA ITCQEIKENE SALDKEEIAN ASADVPSDNV EELGLKYEKQ
860 870 880 890 900
EHRAEKSRSR SSHRQTQSGS LDSDSTSDQH RSRERRSRHK IRSGTPGSDS
910 920 930 940 950
SIEHHRSKKR KSHSKHRTRR SRSPYADSSD SQYTKRKHRE KRHHRTRNPD
960 970 980
TDSSDHEYEE RHKSSSRRSS DKDRSRRRSR HHKR
Length:984
Mass (Da):111,299
Last modified:October 11, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i48A380113E6E459E
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AP004728 Genomic DNA Translation: BAD37703.1
AP008212 Genomic DNA Translation: BAF19586.1
AP014962 Genomic DNA Translation: BAS97851.1
CM000143 Genomic DNA Translation: EEE65748.1
AK103574 mRNA Translation: BAG96148.1

NCBI Reference Sequences

More...
RefSeqi
XP_015643958.1, XM_015788472.1

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
Os06t0489200-01; Os06t0489200-01; Os06g0489200

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
4341077

Gramene; a comparative resource for plants

More...
Gramenei
Os06t0489200-01; Os06t0489200-01; Os06g0489200

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
osa:4341077

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP004728 Genomic DNA Translation: BAD37703.1
AP008212 Genomic DNA Translation: BAF19586.1
AP014962 Genomic DNA Translation: BAS97851.1
CM000143 Genomic DNA Translation: EEE65748.1
AK103574 mRNA Translation: BAG96148.1
RefSeqiXP_015643958.1, XM_015788472.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi4530.OS06T0489200-01

PTM databases

iPTMnetiQ67VW6

Proteomic databases

PaxDbiQ67VW6

Genome annotation databases

EnsemblPlantsiOs06t0489200-01; Os06t0489200-01; Os06g0489200
GeneIDi4341077
GrameneiOs06t0489200-01; Os06t0489200-01; Os06g0489200
KEGGiosa:4341077

Phylogenomic databases

eggNOGiKOG2138, Eukaryota
HOGENOMiCLU_008613_0_0_1
InParanoidiQ67VW6
KOiK13123
OMAiPRSKMDS
OrthoDBi1175081at2759

Gene expression databases

GenevisibleiQ67VW6, OS

Family and domain databases

Gene3Di1.10.10.790, 1 hit
InterProiView protein in InterPro
IPR011666, DUF1604
IPR000467, G_patch_dom
IPR040058, GPATCH1
IPR000061, Surp
IPR035967, SWAP/Surp_sf
PANTHERiPTHR13384:SF19, PTHR13384:SF19, 1 hit
PfamiView protein in Pfam
PF07713, DUF1604, 1 hit
PF01805, Surp, 1 hit
SMARTiView protein in SMART
SM00648, SWAP, 1 hit
SUPFAMiSSF109905, SSF109905, 1 hit
PROSITEiView protein in PROSITE
PS50174, G_PATCH, 1 hit
PS50128, SURP, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTGHH_ORYSJ
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q67VW6
Secondary accession number(s): A0A0P0WX43
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 7, 2015
Last sequence update: October 11, 2004
Last modified: August 12, 2020
This is version 114 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
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