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Entry version 119 (12 Aug 2020)
Sequence version 1 (11 Oct 2004)
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Protein

Bactericidal permeability-increasing protein

Gene

Bpi

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionAntibiotic, Antimicrobial

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-166016, Toll Like Receptor 4 (TLR4) Cascade
R-MMU-6798695, Neutrophil degranulation
R-MMU-6803157, Antimicrobial peptides

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Bactericidal permeability-increasing protein
Short name:
BPI
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Bpi
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:3045315, Bpi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane, Secreted

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 27Sequence analysisAdd BLAST27
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000035833228 – 483Bactericidal permeability-increasing proteinAdd BLAST456

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi161 ↔ 201By similarity
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi375N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi389N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q67E05

PRoteomics IDEntifications database

More...
PRIDEi
Q67E05

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...
GlyGeni
Q67E05, 2 sites

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q67E05

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q67E05

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in testis, epididymis, and bone marrow, as well as in Sertoli and promyelocytic cell lines. Upon stimulation with different TLR ligands, it is strongly expressed in granulocytes and in bone marrow-derived dendritic cells.2 Publications

<p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

By lipopolysaccharide (LPS) through TRL4-TRIF-dependent pathway. Expression in Sertoli and promyelocytic cells is enhanced several-fold by all-trans retinoic acid.2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000052922, Expressed in spermatocyte and 17 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Monomer. Homodimer; disulfide-linked (By similarity).

By similarity

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000067837

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q67E05, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q67E05

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni28 – 38Central sheet, part 1By similarityAdd BLAST11
Regioni37 – 219N-terminal barrelBy similarityAdd BLAST183
Regioni221 – 285Central sheet, part 2By similarityAdd BLAST65
Regioni235 – 240Cleavage sites for elastaseBy similarity6
Regioni286 – 457C-terminal barrelBy similarityAdd BLAST172
Regioni464 – 483Central sheet, part 3By similarityAdd BLAST20

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The N-terminal region may be exposed to the interior of the granule, whereas the C-terminal portion may be embedded in the membrane. During phagocytosis and degranulation, proteases may be released and activated and cleave BPI at the junction of the N- and C-terminal portions of the molecule, providing controlled release of the N-terminal antibacterial fragment when bacteria are ingested (By similarity).By similarity
The N- and C-terminal barrels adopt an identical fold despite having only 13% of conserved residues.By similarity

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4160, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT01000000214575

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_028970_3_2_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q67E05

Identification of Orthologs from Complete Genome Data

More...
OMAi
SCSTHID

Database of Orthologous Groups

More...
OrthoDBi
1242894at2759

TreeFam database of animal gene trees

More...
TreeFami
TF315617

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR017943, Bactericidal_perm-incr_a/b_dom
IPR030181, BPI
IPR030675, BPI/LBP
IPR001124, Lipid-bd_serum_glycop_C
IPR017942, Lipid-bd_serum_glycop_N

The PANTHER Classification System

More...
PANTHERi
PTHR10504:SF84, PTHR10504:SF84, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01273, LBP_BPI_CETP, 1 hit
PF02886, LBP_BPI_CETP_C, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF002417, Lipid_binding_protein, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00328, BPI1, 1 hit
SM00329, BPI2, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF55394, SSF55394, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q67E05-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MTWAPDNVRK WSALLLLAII GTALTAATDP GFVAMISQKG LDFACQQGVV
60 70 80 90 100
ELQKELQAIS VPDFSGVFKI KHLGKGSYEF YSMAVDGFHI PNPKIEMLPS
110 120 130 140 150
DGLRVFIKDA SIKINGKWMS RKNFLKAGGN FELSIQGVSI STDLILGSDS
160 170 180 190 200
SGHITTICSN CDSHIDSVHI KISGSMLGWL IRLFHRKIET SLKNIIYKKI
210 220 230 240 250
CKIVRDSVSS KLQPYLKTLS VITRVDDVTS VDYSLLAPLT TTNQFLEGQL
260 270 280 290 300
KGEFFWRGHR DPLPIHPPVM RFVPNGAYMV CMGISDYFFN TEVLAYQQSG
310 320 330 340 350
TLKMTLGGQL LSNNGRFQLN TDFLRTFLPK VAKMFPSMGV QLLISAPVPV
360 370 380 390 400
HLSIQPSGLS FNPKLETQAF VVLPNASLVP LFVLGMKTNA SLEVDAEENR
410 420 430 440 450
LVGEMKLGSR WLLELKESKF GPFKVEYLED VINYLVSTLV LPKINERLRR
460 470 480
GFPLPLPAGI RFSHFTFYPY QNFLLLEADL HLI
Length:483
Mass (Da):53,940
Last modified:October 11, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4AA2D48095C52B74
GO
Isoform 2 (identifier: Q67E05-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     409-409: Missing.

Show »
Length:482
Mass (Da):53,853
Checksum:i5AA75217D0F72260
GO
Isoform 3 (identifier: Q67E05-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     386-386: M → MVRR

Show »
Length:486
Mass (Da):54,352
Checksum:i9D8F627EA5496D62
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_036069386M → MVRR in isoform 3. 1 Publication1
Alternative sequenceiVSP_036070409Missing in isoform 2. Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY853179 mRNA Translation: AAW50819.1
AY648037 mRNA Translation: AAV65841.1
AY363993 mRNA Translation: AAR13289.1
AK033770 mRNA Translation: BAC28468.1
AL663063 Genomic DNA No translation available.
BC118049 mRNA Translation: AAI18050.1
BC118504 mRNA Translation: AAI18505.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS16987.1 [Q67E05-3]
CCDS89574.1 [Q67E05-1]

NCBI Reference Sequences

More...
RefSeqi
NP_808518.1, NM_177850.3 [Q67E05-3]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000065039; ENSMUSP00000067837; ENSMUSG00000052922 [Q67E05-3]
ENSMUST00000109499; ENSMUSP00000105125; ENSMUSG00000052922 [Q67E05-1]
ENSMUST00000109500; ENSMUSP00000105126; ENSMUSG00000052922 [Q67E05-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
329547

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:329547

UCSC genome browser

More...
UCSCi
uc008npw.1, mouse [Q67E05-3]
uc008npx.1, mouse [Q67E05-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY853179 mRNA Translation: AAW50819.1
AY648037 mRNA Translation: AAV65841.1
AY363993 mRNA Translation: AAR13289.1
AK033770 mRNA Translation: BAC28468.1
AL663063 Genomic DNA No translation available.
BC118049 mRNA Translation: AAI18050.1
BC118504 mRNA Translation: AAI18505.1
CCDSiCCDS16987.1 [Q67E05-3]
CCDS89574.1 [Q67E05-1]
RefSeqiNP_808518.1, NM_177850.3 [Q67E05-3]

3D structure databases

SMRiQ67E05
ModBaseiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000067837

PTM databases

GlyGeniQ67E05, 2 sites
iPTMnetiQ67E05
PhosphoSitePlusiQ67E05

Proteomic databases

PaxDbiQ67E05
PRIDEiQ67E05

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
26835, 342 antibodies

Genome annotation databases

EnsembliENSMUST00000065039; ENSMUSP00000067837; ENSMUSG00000052922 [Q67E05-3]
ENSMUST00000109499; ENSMUSP00000105125; ENSMUSG00000052922 [Q67E05-1]
ENSMUST00000109500; ENSMUSP00000105126; ENSMUSG00000052922 [Q67E05-2]
GeneIDi329547
KEGGimmu:329547
UCSCiuc008npw.1, mouse [Q67E05-3]
uc008npx.1, mouse [Q67E05-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
671
MGIiMGI:3045315, Bpi

Phylogenomic databases

eggNOGiKOG4160, Eukaryota
GeneTreeiENSGT01000000214575
HOGENOMiCLU_028970_3_2_1
InParanoidiQ67E05
OMAiSCSTHID
OrthoDBi1242894at2759
TreeFamiTF315617

Enzyme and pathway databases

ReactomeiR-MMU-166016, Toll Like Receptor 4 (TLR4) Cascade
R-MMU-6798695, Neutrophil degranulation
R-MMU-6803157, Antimicrobial peptides

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
329547, 1 hit in 18 CRISPR screens

Protein Ontology

More...
PROi
PR:Q67E05
RNActiQ67E05, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000052922, Expressed in spermatocyte and 17 other tissues

Family and domain databases

InterProiView protein in InterPro
IPR017943, Bactericidal_perm-incr_a/b_dom
IPR030181, BPI
IPR030675, BPI/LBP
IPR001124, Lipid-bd_serum_glycop_C
IPR017942, Lipid-bd_serum_glycop_N
PANTHERiPTHR10504:SF84, PTHR10504:SF84, 1 hit
PfamiView protein in Pfam
PF01273, LBP_BPI_CETP, 1 hit
PF02886, LBP_BPI_CETP_C, 1 hit
PIRSFiPIRSF002417, Lipid_binding_protein, 1 hit
SMARTiView protein in SMART
SM00328, BPI1, 1 hit
SM00329, BPI2, 1 hit
SUPFAMiSSF55394, SSF55394, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiBPI_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q67E05
Secondary accession number(s): A2AC63, Q5I5I4, Q8BSF3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 16, 2008
Last sequence update: October 11, 2004
Last modified: August 12, 2020
This is version 119 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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