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Protein

Zinc finger protein 385C

Gene

ZNF385C

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri79 – 109Matrin-type 1Add BLAST31
Zinc fingeri227 – 261Matrin-type 2Add BLAST35
Zinc fingeri292 – 322Matrin-type 3Add BLAST31

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger protein 385CImported
Gene namesi
Name:ZNF385CImported
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

EuPathDBiHostDB:ENSG00000187595.14
HGNCiHGNC:33722 ZNF385C
neXtProtiNX_Q66K41

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000187595

Polymorphism and mutation databases

DMDMi172044654

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003199411 – 424Zinc finger protein 385CAdd BLAST424

Proteomic databases

PaxDbiQ66K41
PRIDEiQ66K41
ProteomicsDBi65953
65954 [Q66K41-2]

PTM databases

iPTMnetiQ66K41
PhosphoSitePlusiQ66K41

Expressioni

Gene expression databases

BgeeiENSG00000187595
CleanExiHS_ZNF385C

Interactioni

Binary interactionsi

Show more details

GO - Molecular functioni

Protein-protein interaction databases

IntActiQ66K41, 11 interactors

Structurei

3D structure databases

ProteinModelPortaliQ66K41
SMRiQ66K41
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi131 – 203Pro-richAdd BLAST73

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri79 – 109Matrin-type 1Add BLAST31
Zinc fingeri227 – 261Matrin-type 2Add BLAST35
Zinc fingeri292 – 322Matrin-type 3Add BLAST31

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiENOG410IGA9 Eukaryota
ENOG410ZUZY LUCA
GeneTreeiENSGT00390000002371
HOGENOMiHOG000231865
HOVERGENiHBG054524
InParanoidiQ66K41
PhylomeDBiQ66K41

Family and domain databases

InterProiView protein in InterPro
IPR003604 Matrin/U1-like-C_Znf_C2H2
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 3 hits
SM00451 ZnF_U1, 3 hits
SUPFAMiSSF57667 SSF57667, 3 hits

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q66K41-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MGLAAGPASG APSPLLASLP LPTRPLQPPL DFKHLLAFHF NGAAPLSLFP
60 70 80 90 100
NFSTMDPVQK AVISHTFGVP SPLKKKLFIS CNICHLRFNS ANQAEAHYKG
110 120 130 140 150
HKHARKLKAV EAAKSKQRPH TQAQDGAVVS PIPTLASGAP GEPQSKVPAA
160 170 180 190 200
PPLGPPLQPP PTPDPTCREP AHSELLDAAS SSSSSSCPPC SPEPGREAPG
210 220 230 240 250
PEPAAAAVGS SMSGEGRSEK GHLYCPTCKV TVNSASQLQA HNTGAKHRWM
260 270 280 290 300
MEGQRGAPRR SRGRPVSRGG AGHKAKRVTG GRGGRQGPSP AFHCALCQLQ
310 320 330 340 350
VNSETQLKQH MSSRRHKDRL AGKTPKPSSQ HSKLQKHAAL AVSILKSKLA
360 370 380 390 400
LQKQLTKTLA ARFLPSPLPT AATAICALPG PLALRPAPTA ATTLFPAPIL
410 420
GPALFRTPAG AVRPATGPIV LAPY
Length:424
Mass (Da):44,235
Last modified:March 28, 2018 - v3
Checksum:i05C6D62D583CB61E
GO
Isoform 2 (identifier: Q66K41-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-250: Missing.

Note: No experimental confirmation available.
Show »
Length:174
Mass (Da):18,242
Checksum:i6C71BB717FD1D50D
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0315461 – 250Missing in isoform 2. 1 PublicationAdd BLAST250

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC105024 Genomic DNA No translation available.
BC080613 mRNA Translation: AAH80613.1
CCDSiCCDS74065.1 [Q66K41-1]
RefSeqiNP_001229633.1, NM_001242704.1 [Q66K41-1]
UniGeneiHs.443140

Genome annotation databases

EnsembliENST00000618554; ENSP00000480744; ENSG00000187595 [Q66K41-1]
GeneIDi201181
KEGGihsa:201181

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Entry informationi

Entry nameiZ385C_HUMAN
AccessioniPrimary (citable) accession number: Q66K41
Secondary accession number(s): A0A087WX54, Q4G0J1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: March 28, 2018
Last modified: July 18, 2018
This is version 112 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM

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