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Entry version 115 (07 Apr 2021)
Sequence version 3 (27 Jul 2011)
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Protein

Kinetochore scaffold 1

Gene

Knl1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Performs two crucial functions during mitosis: it is essential for spindle-assembly checkpoint signaling and for correct chromosome alignment. Directly links spindle checkpoint proteins BUB1 and BUB1B to kinetochores. Part of the MIS12 complex, which may be fundamental for kinetochore formation and proper chromosome segregation during mitosis. Acts in coordination with CENPK to recruit the NDC80 complex to the outer kinetochore (By similarity).By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCell cycle, Cell division, Chromosome partition, Mitosis

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-141444, Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
R-MMU-2467813, Separation of Sister Chromatids
R-MMU-2500257, Resolution of Sister Chromatid Cohesion
R-MMU-5663220, RHO GTPases Activate Formins
R-MMU-606279, Deposition of new CENPA-containing nucleosomes at the centromere
R-MMU-68877, Mitotic Prometaphase
R-MMU-9648025, EML4 and NUDC in mitotic spindle formation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Kinetochore scaffold 1
Alternative name(s):
Cancer susceptibility candidate gene 5 protein homolog
Kinetochore-null protein 1
Protein CASC5
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Knl1Imported
Synonyms:Casc5
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1923714, Knl1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Centromere, Chromosome, Kinetochore, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002359831 – 1612Kinetochore scaffold 1Add BLAST1612

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei32PhosphoserineBy similarity1
Modified residuei60PhosphoserineBy similarity1
Modified residuei538PhosphoserineBy similarity1
Modified residuei540PhosphothreonineBy similarity1
Modified residuei794PhosphoserineCombined sources1
Modified residuei878PhosphoserineBy similarity1
Modified residuei1243PhosphoserineBy similarity1
Modified residuei1464PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q66JQ7

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q66JQ7

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q66JQ7

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q66JQ7

PRoteomics IDEntifications database

More...
PRIDEi
Q66JQ7

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
264789

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q66JQ7

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q66JQ7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000027326, Expressed in forelimb bud and 152 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q66JQ7, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q66JQ7, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with DSN1, MIS12, BUB1, BUB1B, NSL1 and ZWINT.

By similarity

Protein-protein interaction databases

ComplexPortal: manually curated resource of macromolecular complexes

More...
ComplexPortali
CPX-5702, Kinetochore KNL1 complex

Protein interaction database and analysis system

More...
IntActi
Q66JQ7, 15 interactors

Molecular INTeraction database

More...
MINTi
Q66JQ7

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000028802

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q66JQ7, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q66JQ7

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati723 – 8271Add BLAST105
Repeati923 – 10272Add BLAST105

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni723 – 10272 X 104 AA approximate repeatsAdd BLAST305

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi1577 – 1590Nuclear localization signalSequence analysisAdd BLAST14

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QW5H, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00410000025918

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q66JQ7

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR037388, Blinkin
IPR043651, KNL1_MELT_rep

The PANTHER Classification System

More...
PANTHERi
PTHR16520, PTHR16520, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF19221, MELT, 9 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

Q66JQ7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDGVYSEANE ENDNTQRPVR RQHSSILKPP RSPLQDLKCG NQTNQEPNPP
60 70 80 90 100
RKRKSSRRVS FADTIKVFQT ESHMKTERNS EISGMNTLLC APIQTQMQQK
110 120 130 140 150
EFSITDCNHE RKHANDQTVI FSDENQMDLT ASHTVMITKG LSDCTKNENS
160 170 180 190 200
TKIDTTSFLE NLKHHAANSR IKKDLACSTV SLSQNIFSEK INSDNFIKRL
210 220 230 240 250
KTGKHISSST ELDKENAEIP VYSKDSNSAS STYQMHASLG VDENSSNRTR
260 270 280 290 300
IFREQDDGMN LTQCHTACIK TWIPPSTEAK IGEFKGDKTI YGNECMELTT
310 320 330 340 350
NYTIQVLSSE NNLSERETQT QNGMNVTTVD GATAPAPEKK TALKDKLNAA
360 370 380 390 400
FQGSFPNPEN KIHIIKCHPI ESETHTVTQI SSQSASTLAV TSKSICSSPA
410 420 430 440 450
IEGYKTIFHS SSNDAMELTK CLSAMEEEKK LLKADDKYSK ICTNPDAGPL
460 470 480 490 500
REKTIYLEED SMDITKSHTV AIDNKIFKHD QENIKKEIIA IPIFEKEMVL
510 520 530 540 550
RNLMPMSKDE KRDVNYISVP QVSKESLQRS QTNTLSVSLT DKKMEFLADE
560 570 580 590 600
DMDLTKSHTT KLSQVIPTTF DLASKNVTKS YSHSKSPLNE WESLDKQVVL
610 620 630 640 650
GQHSKLPLPQ RKDRDDPDCS HHKIMYSEEL QTMDLTKSHT IVIGFGPSEV
660 670 680 690 700
QEHSKINLEH KNSQLTAESI QTAVNVPAAN SRVVTTNDMD MLKDRSTHKP
710 720 730 740 750
ELLKEKQNIK IYGRKSIGRL KIDKTILFSE GNEGDMDITK SCTVKINHRS
760 770 780 790 800
LLDKHDSHLV SLAGTSKTIL HARGQVEMEI NRSHTTPLEC KIISPSDITP
810 820 830 840 850
GDLDKTMMSI DDHEELDMTK SHTVFIDYQA EAKGVLPDRL DFQLSKKESL
860 870 880 890 900
QKPKVTSLAE EIYISKNSES NHLPAKGSQL TILEEGSNSG LGEETNDAQK
910 920 930 940 950
PGFLNELLSG KTQRRKSLSL KNKSITFPEN DKSYREIPQS SAVEINNETR
960 970 980 990 1000
LEDRKGFSFV PLAGTSKPVL SAYGPEDMEI SIGQTTASEY KTVPPEEITT
1010 1020 1030 1040 1050
IPMDKTVMFV DNFGDLDVTR SHTVFIDCQA KEKVLDEYTN LGIQKTKTLS
1060 1070 1080 1090 1100
GSEGDTHIQE ITKNPAAQHK HHMTTVIPSS TVVSDQSSMK IKFHKADRDE
1110 1120 1130 1140 1150
EVKGKEVEAN MLKQTKPESC LLNITDGKNV DFTSSYTADV CRSSDKYSSL
1160 1170 1180 1190 1200
PNISSSDNSG GNTMSLCDKN KEKAYNCQVP NEFTYAAILP STYHMDSKKL
1210 1220 1230 1240 1250
SVFPPCPSKE VTQTESAIAL LKDEDPVEEP LGEMATFNSK HVSLNLAKDQ
1260 1270 1280 1290 1300
TEAFVDVSVA SQPHLSAQQS PSTQKGQDVA RRDEGILAKA GKKALPFLLE
1310 1320 1330 1340 1350
NVAASTWENE SKIPTNVEHF AVTYEKELSI SIQTDKCNTN VQSPSNSALT
1360 1370 1380 1390 1400
TQVIQTHANA EGALDFLVPS TVSCFSSTKP SLSNLNRKTE EVLDFQTVNL
1410 1420 1430 1440 1450
LPPAEQLLEE GSQAHSMSIV QATEIYRLGS RNDRDEESKT FCNEAETTSV
1460 1470 1480 1490 1500
PLKTAVKDKT RRCSLGIFLP KLPSKRSCSI TGVDDLEQIL ADAADLTQLE
1510 1520 1530 1540 1550
TQPVCSKDPG IGSVAAKLNL SPSQFINEEN LPVYPGEILS SDSVSLDIEE
1560 1570 1580 1590 1600
SVLIDTSQRE SLPSENKTEN CRAQKRTRVE ENDVTNEKKI RTHDSAQDQE
1610
VSCLEPKNVL EF
Length:1,612
Mass (Da):179,337
Last modified:July 27, 2011 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA9BE2BB20E008621
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A3KGI3A3KGI3_MOUSE
Kinetochore scaffold 1
Knl1
2,119Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A3KGI5A3KGI5_MOUSE
Kinetochore scaffold 1
Knl1
484Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A3KGI6A3KGI6_MOUSE
Kinetochore scaffold 1
Knl1
91Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti128D → G in AAH80815 (PubMed:15489334).Curated1
Sequence conflicti375H → R in AAH80815 (PubMed:15489334).Curated1
Sequence conflicti1151P → L in AAH80815 (PubMed:15489334).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL772264 Genomic DNA No translation available.
BC080815 mRNA Translation: AAH80815.1
AK009772 mRNA Translation: BAB26494.1
AK033132 mRNA Translation: BAC28167.2

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS89540.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000028799; ENSMUSP00000028799; ENSMUSG00000027326

UCSC genome browser

More...
UCSCi
uc008ltb.1, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL772264 Genomic DNA No translation available.
BC080815 mRNA Translation: AAH80815.1
AK009772 mRNA Translation: BAB26494.1
AK033132 mRNA Translation: BAC28167.2
CCDSiCCDS89540.1

3D structure databases

SMRiQ66JQ7
ModBaseiSearch...

Protein-protein interaction databases

ComplexPortaliCPX-5702, Kinetochore KNL1 complex
IntActiQ66JQ7, 15 interactors
MINTiQ66JQ7
STRINGi10090.ENSMUSP00000028802

PTM databases

iPTMnetiQ66JQ7
PhosphoSitePlusiQ66JQ7

Proteomic databases

EPDiQ66JQ7
jPOSTiQ66JQ7
MaxQBiQ66JQ7
PaxDbiQ66JQ7
PRIDEiQ66JQ7
ProteomicsDBi264789

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
23122, 111 antibodies

Genome annotation databases

EnsembliENSMUST00000028799; ENSMUSP00000028799; ENSMUSG00000027326
UCSCiuc008ltb.1, mouse

Organism-specific databases

MGIiMGI:1923714, Knl1

Phylogenomic databases

eggNOGiENOG502QW5H, Eukaryota
GeneTreeiENSGT00410000025918
InParanoidiQ66JQ7

Enzyme and pathway databases

ReactomeiR-MMU-141444, Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
R-MMU-2467813, Separation of Sister Chromatids
R-MMU-2500257, Resolution of Sister Chromatid Cohesion
R-MMU-5663220, RHO GTPases Activate Formins
R-MMU-606279, Deposition of new CENPA-containing nucleosomes at the centromere
R-MMU-68877, Mitotic Prometaphase
R-MMU-9648025, EML4 and NUDC in mitotic spindle formation

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Knl1, mouse

Protein Ontology

More...
PROi
PR:Q66JQ7
RNActiQ66JQ7, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000027326, Expressed in forelimb bud and 152 other tissues
ExpressionAtlasiQ66JQ7, baseline and differential
GenevisibleiQ66JQ7, MM

Family and domain databases

InterProiView protein in InterPro
IPR037388, Blinkin
IPR043651, KNL1_MELT_rep
PANTHERiPTHR16520, PTHR16520, 1 hit
PfamiView protein in Pfam
PF19221, MELT, 9 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiKNL1_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q66JQ7
Secondary accession number(s): A3KGI4, Q8CCH6, Q9CV38
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 16, 2006
Last sequence update: July 27, 2011
Last modified: April 7, 2021
This is version 115 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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