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Protein
Submitted name:

Serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium-derived factor), member 1

Gene

serpinf1

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Protein family/group databases

MEROPSiI04.979

Names & Taxonomyi

Protein namesi
Submitted name:
Serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium-derived factor), member 1Imported
Submitted name:
Zgc:92072Imported
Gene namesi
Name:serpinf1Imported
ORF Names:zgc:92072Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 21

Organism-specific databases

ZFINiZDB-GENE-040912-2 serpinf1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_501509812320 – 406Sequence analysisAdd BLAST387

Expressioni

Gene expression databases

BgeeiENSDARG00000069048 Expressed in 23 organ(s), highest expression level in zone of skin

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000090939

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini53 – 403SERPINInterPro annotationAdd BLAST351

Sequence similaritiesi

Belongs to the serpin family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG2392 Eukaryota
COG4826 LUCA
GeneTreeiENSGT00920000149046
HOGENOMiHOG000115489
HOVERGENiHBG106911
KOiK19614
OMAiLNCKIAQ
OrthoDBiEOG091G09UU
TreeFamiTF317350

Family and domain databases

CDDicd02052 PEDF, 1 hit
InterProiView protein in InterPro
IPR033832 PEDF
IPR023795 Serpin_CS
IPR023796 Serpin_dom
IPR000215 Serpin_fam
IPR036186 Serpin_sf
PANTHERiPTHR11461 PTHR11461, 1 hit
PfamiView protein in Pfam
PF00079 Serpin, 1 hit
SMARTiView protein in SMART
SM00093 SERPIN, 1 hit
SUPFAMiSSF56574 SSF56574, 1 hit
PROSITEiView protein in PROSITE
PS00284 SERPIN, 1 hit

Sequencei

Sequence statusi: Complete.

Q66I20-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKKIVLLVGL WSLLSLSHAQ LADTTDAEGE EEAVDLFTTP RTKLAAATSD
60 70 80 90 100
FGYNLFRQLA SRDTKASVFL SPMSISAAFT QLSMGASERA EKQIYRALRY
110 120 130 140 150
HTLQDSQLHD TLRDLLSSLR ASAKGFKSAE RILLARKLRL RLEYLNSVEK
160 170 180 190 200
QYGERPQILA GGARDLKTVN DWFKQQTGGK VDQVVPSPLP RNTALLPVGS
210 220 230 240 250
AYFKGKWITR FGKPNKMETF RRDGQAPAVI PMMEQENYPV KMGIDSDLGC
260 270 280 290 300
TIAQVPMEDG VSMYFFLPDE VTQNLTLIEE ALTAEFVQDL SNSLHTVKVL
310 320 330 340 350
LTLPVIKLSY KTNLLPSLSD LGLSEWLAET DLTKITSQPV KLNAVHHKVV
360 370 380 390 400
LETAPEGAEY ASTTPSATGQ SLGLSYRVDR PFLFLVRDEP SGALLFIGKV

LNPSDL
Length:406
Mass (Da):44,954
Last modified:October 11, 2004 - v1
Checksum:iF93DD6CA4ADE5404
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX248108 Genomic DNA No translation available.
BC081582 mRNA Translation: AAH81582.1
BC155160 mRNA Translation: AAI55161.1
RefSeqiNP_001004539.1, NM_001004539.1
UniGeneiDr.29881

Genome annotation databases

EnsembliENSDART00000100166; ENSDARP00000090939; ENSDARG00000069048
GeneIDi447800
KEGGidre:447800

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX248108 Genomic DNA No translation available.
BC081582 mRNA Translation: AAH81582.1
BC155160 mRNA Translation: AAI55161.1
RefSeqiNP_001004539.1, NM_001004539.1
UniGeneiDr.29881

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000090939

Protein family/group databases

MEROPSiI04.979

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000100166; ENSDARP00000090939; ENSDARG00000069048
GeneIDi447800
KEGGidre:447800

Organism-specific databases

CTDi5176
ZFINiZDB-GENE-040912-2 serpinf1

Phylogenomic databases

eggNOGiKOG2392 Eukaryota
COG4826 LUCA
GeneTreeiENSGT00920000149046
HOGENOMiHOG000115489
HOVERGENiHBG106911
KOiK19614
OMAiLNCKIAQ
OrthoDBiEOG091G09UU
TreeFamiTF317350

Gene expression databases

BgeeiENSDARG00000069048 Expressed in 23 organ(s), highest expression level in zone of skin

Family and domain databases

CDDicd02052 PEDF, 1 hit
InterProiView protein in InterPro
IPR033832 PEDF
IPR023795 Serpin_CS
IPR023796 Serpin_dom
IPR000215 Serpin_fam
IPR036186 Serpin_sf
PANTHERiPTHR11461 PTHR11461, 1 hit
PfamiView protein in Pfam
PF00079 Serpin, 1 hit
SMARTiView protein in SMART
SM00093 SERPIN, 1 hit
SUPFAMiSSF56574 SSF56574, 1 hit
PROSITEiView protein in PROSITE
PS00284 SERPIN, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ66I20_DANRE
AccessioniPrimary (citable) accession number: Q66I20
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2004
Last sequence update: October 11, 2004
Last modified: October 10, 2018
This is version 113 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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