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UniProtKB - Q66H34 (CFA97_RAT)

Entry version 80 (02 Dec 2020)
Sequence version 1 (11 Oct 2004)
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Protein

Cilia- and flagella-associated protein 97

Gene

Cfap97

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Cilia- and flagella-associated protein 97Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Cfap97Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRattus norvegicus (Rat)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10116 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002494 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 16

Organism-specific databases

Rat genome database

More...RGDi		1307325, Cfap97

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003092271 – 548Cilia- and flagella-associated protein 97CuratedAdd BLAST548

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei8PhosphoserineCombined sources1
Modified residuei19PhosphoserineCombined sources1
Modified residuei155PhosphothreonineBy similarity1
Modified residuei160PhosphoserineCombined sources1
Modified residuei161PhosphoserineCombined sources1
Modified residuei235PhosphoserineBy similarity1
Modified residuei259PhosphoserineCombined sources1

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q66H34

PRoteomics IDEntifications database

More...PRIDEi		Q66H34

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q66H34

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q66H34

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSRNOG00000032192, Expressed in testis and 22 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q66H34, RN

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		10116.ENSRNOP00000042262

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q66H34

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili383 – 460Sequence analysisAdd BLAST78

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi171 – 247Ser-richAdd BLAST77

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the CFAP97 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502S0ZF, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000010356

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_040301_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q66H34

Identification of Orthologs from Complete Genome Data

More...OMAi		DHRYKQK

Database of Orthologous Groups

More...OrthoDBi		947267at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q66H34

TreeFam database of animal gene trees

More...TreeFami		TF336369

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR038791, Cfap97/Hemingway
IPR029488, Hmw/CFAP97D1

The PANTHER Classification System

More...PANTHERi		PTHR23035, PTHR23035, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF13879, KIAA1430, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q66H34-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDRFGDISEG EVDHSFFDSD FEDTKKCESN SIFDKQNDDD FKEGINKDIK 
        60         70         80         90        100
NLNLKFGVQN DNLKEKIDND TENVNVKLGI QTKENYLTQK GNERKPKFPS 
       110        120        130        140        150
KEQHVENDPI QTRSPSLLTS SRSKKLCDTT KGNKLHLPVP NRIPKIVKGE 
       160        170        180        190        200
DDYYTDGEES SDDGKKYHVR SKSAKPSSNL KKNNTSKKYS KASSSSLSSS 
       210        220        230        240        250
SSRSSSDCSD IGSDMQNKPD SGSSGKRVSS VTPSSPKQKC KSGRKSSAKQ 
       260        270        280        290        300
KAGDYNAESE DNVTDVTPAS TPDSSPAQPF ELSQSQNQKV KVKRQENVSR 
       310        320        330        340        350
DVYEDVEALK NDSRCLKSAK RKEKHGQNFA PKSSVLDANL DRRSKQKVLH 
       360        370        380        390        400
DTMDLNHLLK AFLQLDKKGP QKHHFEQPSI IPRKNYSFTR EEVRQIDREN 
       410        420        430        440        450
QRLLKELSRQ AEKPGNKSTI PGRSLGHPPK LYHSALNRQR EQQRIERENM 
       460        470        480        490        500
ALLKRLEAVK PTVGMKRSEQ LMDYHRNISY LNPSPSVRRV RSTLGHYSPL 
       510        520        530        540 
RGASRTSSAT SGLSCKTDRS VLDTSSGFLL RPKPPNIQCS NSKVLRSH
Length:548
Mass (Da):61,743
Last modified:October 11, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0E89BCE48AC16F38
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
BC082052 mRNA Translation: AAH82052.1

NCBI Reference Sequences

More...RefSeqi		NP_001014023.1, NM_001014001.1
XP_008769484.1, XM_008771262.1
XP_008769485.1, XM_008771263.1
XP_008769486.1, XM_008771264.2
XP_017455608.1, XM_017600119.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSRNOT00000045721; ENSRNOP00000042262; ENSRNOG00000032192

Database of genes from NCBI RefSeq genomes

More...GeneIDi		306469

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		rno:306469

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC082052 mRNA Translation: AAH82052.1
RefSeqiNP_001014023.1, NM_001014001.1
XP_008769484.1, XM_008771262.1
XP_008769485.1, XM_008771263.1
XP_008769486.1, XM_008771264.2
XP_017455608.1, XM_017600119.1

3D structure databases

SMRiQ66H34
ModBaseiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000042262

PTM databases

iPTMnetiQ66H34
PhosphoSitePlusiQ66H34

Proteomic databases

PaxDbiQ66H34
PRIDEiQ66H34

Genome annotation databases

EnsembliENSRNOT00000045721; ENSRNOP00000042262; ENSRNOG00000032192
GeneIDi306469
KEGGirno:306469

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		57587
RGDi1307325, Cfap97

Phylogenomic databases

eggNOGiENOG502S0ZF, Eukaryota
GeneTreeiENSGT00390000010356
HOGENOMiCLU_040301_1_0_1
InParanoidiQ66H34
OMAiDHRYKQK
OrthoDBi947267at2759
PhylomeDBiQ66H34
TreeFamiTF336369

Miscellaneous databases

Protein Ontology

More...PROi		PR:Q66H34

Gene expression databases

BgeeiENSRNOG00000032192, Expressed in testis and 22 other tissues
GenevisibleiQ66H34, RN

Family and domain databases

InterProiView protein in InterPro
IPR038791, Cfap97/Hemingway
IPR029488, Hmw/CFAP97D1
PANTHERiPTHR23035, PTHR23035, 1 hit
PfamiView protein in Pfam
PF13879, KIAA1430, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCFA97_RAT
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q66H34
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: October 11, 2004
Last modified: December 2, 2020
This is version 80 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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