UniProtKB - Q66GN2 (LRK64_ARATH)
Protein
Lectin-domain containing receptor kinase VI.4
Gene
LECRK64
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
Involved in negative regulation of abscisic acid response in seed germination.1 Publication
Catalytic activityi
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 392 | ATPPROSITE-ProRule annotation | 1 | |
Active sitei | 491 | Proton acceptorPROSITE-ProRule annotation | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 369 – 377 | ATPPROSITE-ProRule annotation | 9 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- carbohydrate binding Source: UniProtKB-KW
- protein serine kinase activity Source: UniProtKB-EC
- protein threonine kinase activity Source: UniProtKB-EC
- transmembrane receptor protein serine/threonine kinase activity Source: GO_Central
GO - Biological processi
- abscisic acid-activated signaling pathway Source: TAIR
- defense response to bacterium Source: GO_Central
- defense response to oomycetes Source: GO_Central
- seed germination Source: TAIR
Keywordsi
Molecular function | Kinase, Receptor, Serine/threonine-protein kinase, Transferase |
Ligand | ATP-binding, Lectin, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Lectin-domain containing receptor kinase VI.4 (EC:2.7.11.1)Short name: LecRK-VI.4 Alternative name(s): Lectin receptor kinase A4.3 |
Gene namesi | Name:LECRK64 Synonyms:LECRKA4.3 Ordered Locus Names:At5g01560 ORF Names:F7A7.80 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT5G01560 |
TAIRi | locus:2149810, AT5G01560 |
Subcellular locationi
Plasma membrane
- Cell membrane Curated; Single-pass type I membrane protein Curated
Plasma Membrane
- plasma membrane Source: GO_Central
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 20 – 306 | ExtracellularSequence analysisAdd BLAST | 287 | |
Transmembranei | 307 – 327 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 328 – 691 | CytoplasmicSequence analysisAdd BLAST | 364 |
Keywords - Cellular componenti
Cell membrane, MembranePathology & Biotechi
Disruption phenotypei
Slight enhancement in abscisic acid-inhibited germination. Redundant with LECRKA4.1 and LECRKA4.2.1 Publication
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 19 | Sequence analysisAdd BLAST | 19 | |
ChainiPRO_0000364131 | 20 – 691 | Lectin-domain containing receptor kinase VI.4Add BLAST | 672 |
Proteomic databases
PaxDbi | Q66GN2 |
PRIDEi | Q66GN2 |
ProteomicsDBi | 238723 |
PTM databases
iPTMneti | Q66GN2 |
Expressioni
Gene expression databases
ExpressionAtlasi | Q66GN2, baseline and differential |
Genevisiblei | Q66GN2, AT |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 363 – 641 | Protein kinasePROSITE-ProRule annotationAdd BLAST | 279 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 26 – 273 | Legume-lectin likeAdd BLAST | 248 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 290 – 294 | Poly-Pro | 5 | |
Compositional biasi | 648 – 689 | Ser-richAdd BLAST | 42 |
Sequence similaritiesi
In the C-terminal section; belongs to the protein kinase superfamily. Ser/Thr protein kinase family.Curated
In the N-terminal section; belongs to the leguminous lectin family.Curated
Keywords - Domaini
Signal, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | ENOG502QTCP, Eukaryota |
HOGENOMi | CLU_000288_62_3_1 |
InParanoidi | Q66GN2 |
OMAi | RTPMISQ |
OrthoDBi | 684563at2759 |
PhylomeDBi | Q66GN2 |
Family and domain databases
CDDi | cd06899, lectin_legume_LecRK_Arcelin_ConA, 1 hit |
InterProi | View protein in InterPro IPR013320, ConA-like_dom_sf IPR011009, Kinase-like_dom_sf IPR001220, Legume_lectin_dom IPR000719, Prot_kinase_dom IPR017441, Protein_kinase_ATP_BS IPR008271, Ser/Thr_kinase_AS |
Pfami | View protein in Pfam PF00139, Lectin_legB, 1 hit PF00069, Pkinase, 1 hit |
SMARTi | View protein in SMART SM00220, S_TKc, 1 hit |
SUPFAMi | SSF49899, SSF49899, 1 hit SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS00107, PROTEIN_KINASE_ATP, 1 hit PS50011, PROTEIN_KINASE_DOM, 1 hit PS00108, PROTEIN_KINASE_ST, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
Q66GN2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGRAKSMVSL LLVLFLVRAH VATTETTTEF IFHGFKGNQS EIHMQGDSTI
60 70 80 90 100
TSNGLLRLTD RNSDVVGTAF YHKPVRLLDS NSTNTTVRSF STSFIFIIPS
110 120 130 140 150
SSTSNGGFGF TFTLSPTPNR TDADPEQYMG LLNERNDGNS SNHVFAVEFD
160 170 180 190 200
TVQGFKDGTN RIGNHIGLNF NSLSSDVQEP VAYFNNNDSQ KEEFQLVSGE
210 220 230 240 250
PIQVFLDYHG PTKTLNLTVY PTRLGYKPRI PLISREVPKL SDIVVDEMFV
260 270 280 290 300
GFTAATGRHG QSSAHYVMGW SFASGGEHPL AAMLDISQLP PPPPNKAKKR
310 320 330 340 350
GYNGKVIALI VALSTVISIM LVLLFLFMMY KKRMQQEEIL EDWEIDHPHR
360 370 380 390 400
FRYRDLYKAT EGFKENRVVG TGGFGIVYRG NIRSSSDQIA VKKITPNSMQ
410 420 430 440 450
GVREFVAEIE SLGRLRHKNL VNLQGWCKHR NDLLLIYDYI PNGSLDSLLY
460 470 480 490 500
SKPRRSGAVL SWNARFQIAK GIASGLLYLH EEWEQIVIHR DVKPSNVLID
510 520 530 540 550
SDMNPRLGDF GLARLYERGS QSCTTVVVGT IGYMAPELAR NGNSSSASDV
560 570 580 590 600
FAFGVLLLEI VSGRKPTDSG TFFIADWVME LQASGEILSA IDPRLGSGYD
610 620 630 640 650
EGEARLALAV GLLCCHHKPE SRPLMRMVLR YLNRDEDVPE IHDNWGYSDS
660 670 680 690
SRTDLGSKLV GYISSDRASS SHSHTSSSLT RISSTSLISG R
Sequence cautioni
The sequence CAB82272 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL161946 Genomic DNA Translation: CAB82272.1 Different initiation. CP002688 Genomic DNA Translation: AED90360.1 BT015370 mRNA Translation: AAU05493.1 |
PIRi | T48177 |
RefSeqi | NP_195776.2, NM_120234.4 |
Genome annotation databases
EnsemblPlantsi | AT5G01560.1; AT5G01560.1; AT5G01560 |
GeneIDi | 830345 |
Gramenei | AT5G01560.1; AT5G01560.1; AT5G01560 |
KEGGi | ath:AT5G01560 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL161946 Genomic DNA Translation: CAB82272.1 Different initiation. CP002688 Genomic DNA Translation: AED90360.1 BT015370 mRNA Translation: AAU05493.1 |
PIRi | T48177 |
RefSeqi | NP_195776.2, NM_120234.4 |
3D structure databases
SMRi | Q66GN2 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 3702.AT5G01560.1 |
PTM databases
iPTMneti | Q66GN2 |
Proteomic databases
PaxDbi | Q66GN2 |
PRIDEi | Q66GN2 |
ProteomicsDBi | 238723 |
Genome annotation databases
EnsemblPlantsi | AT5G01560.1; AT5G01560.1; AT5G01560 |
GeneIDi | 830345 |
Gramenei | AT5G01560.1; AT5G01560.1; AT5G01560 |
KEGGi | ath:AT5G01560 |
Organism-specific databases
Araporti | AT5G01560 |
TAIRi | locus:2149810, AT5G01560 |
Phylogenomic databases
eggNOGi | ENOG502QTCP, Eukaryota |
HOGENOMi | CLU_000288_62_3_1 |
InParanoidi | Q66GN2 |
OMAi | RTPMISQ |
OrthoDBi | 684563at2759 |
PhylomeDBi | Q66GN2 |
Miscellaneous databases
PROi | PR:Q66GN2 |
Gene expression databases
ExpressionAtlasi | Q66GN2, baseline and differential |
Genevisiblei | Q66GN2, AT |
Family and domain databases
CDDi | cd06899, lectin_legume_LecRK_Arcelin_ConA, 1 hit |
InterProi | View protein in InterPro IPR013320, ConA-like_dom_sf IPR011009, Kinase-like_dom_sf IPR001220, Legume_lectin_dom IPR000719, Prot_kinase_dom IPR017441, Protein_kinase_ATP_BS IPR008271, Ser/Thr_kinase_AS |
Pfami | View protein in Pfam PF00139, Lectin_legB, 1 hit PF00069, Pkinase, 1 hit |
SMARTi | View protein in SMART SM00220, S_TKc, 1 hit |
SUPFAMi | SSF49899, SSF49899, 1 hit SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS00107, PROTEIN_KINASE_ATP, 1 hit PS50011, PROTEIN_KINASE_DOM, 1 hit PS00108, PROTEIN_KINASE_ST, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | LRK64_ARATH | |
Accessioni | Q66GN2Primary (citable) accession number: Q66GN2 Secondary accession number(s): Q9M019 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 10, 2009 |
Last sequence update: | October 11, 2004 | |
Last modified: | April 7, 2021 | |
This is version 116 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names - SIMILARITY comments
Index of protein domains and families