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Entry version 94 (11 Dec 2019)
Sequence version 1 (01 Nov 1996)
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Protein

RNA-directed RNA polymerase L

Gene

L

Organism
Dugbe virus (isolate ArD44313) (DUGV)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Displays RNA-directed RNA polymerase and deubiquitinating activities. RNA-dependent RNA polymerase is responsible for replication and transcription of the viral RNA genome. The deubiquitinating activity cleaves both ubiquitinated and ISGylated products and may therefore regulate ubiquitin and ISG15 dependent innate immunity (By similarity).By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

  • Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal). EC:3.4.19.12

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei40For ubiquitin thioesterase activityBy similarity1
Active sitei151For ubiquitin thioesterase activityBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase, Nucleotidyltransferase, RNA-directed RNA polymerase, Transferase
Biological processHost-virus interaction, Inhibition of host innate immune response by virus, Inhibition of host interferon signaling pathway by virus, Inhibition of host ISG15 by virus, Modulation of host ubiquitin pathway by viral deubiquitinase, Modulation of host ubiquitin pathway by virus, Viral immunoevasion, Viral RNA replication
LigandNucleotide-binding

Protein family/group databases

MEROPS protease database

More...
MEROPSi
C87.001

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
RNA-directed RNA polymerase L
Short name:
Protein L
Alternative name(s):
Large structural protein
Replicase
Transcriptase
Including the following 2 domains:
Ubiquitin thioesterase (EC:3.4.19.12)
RNA-directed RNA polymerase (EC:2.7.7.48)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:L
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDugbe virus (isolate ArD44313) (DUGV)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri766194 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiVirusesRiboviriaNegarnaviricotaPolyploviricotinaEllioviricetesBunyaviralesNairoviridaeOrthonairovirus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section only exists in viral entries and indicates the host(s) either as a specific organism or taxonomic group of organisms that are susceptible to be infected by a virus.<p><a href='/help/virus_host' target='_top'>More...</a></p>Virus hostiAmblyomma variegatum (Tropical bont tick) [TaxID: 34610]
Homo sapiens (Human) [TaxID: 9606]
Hyalomma rufipes [TaxID: 72862]
Hyalomma truncatum [TaxID: 72855]
Rhipicephalus [TaxID: 34630]
Rhipicephalus annulatus [TaxID: 34611]
Rhipicephalus decoloratus (African blue tick) (Boophilus decoloratus) [TaxID: 60189]
Rhipicephalus geigyi [TaxID: 136141]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000278 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002220261 – 4036RNA-directed RNA polymerase LAdd BLAST4036

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
Q66431

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

14036
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q66431

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini29 – 158OTUPROSITE-ProRule annotationAdd BLAST130
Domaini2424 – 2639RdRp catalyticPROSITE-ProRule annotationAdd BLAST216

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The OTU domain is responsible for the deubiquitinating and deISGylation activities of Nsp2.By similarity

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the nairovirus RNA polymerase family.Curated

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003323 OTU_dom
IPR007099 RNA-dir_pol_NSvirus
IPR007322 RNA_pol_bunyavir

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF04196 Bunya_RdRp, 1 hit
PF02338 OTU, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50802 OTU, 1 hit
PS50525 RDRP_SSRNA_NEG_SEG, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q66431-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDFLDSLIWE RVVDEQYITN PTFCVSDYFE VIRQPGDGNC FYHSIAELFF
60 70 80 90 100
DVKTPSSFRK VKEHLQLAAE VYYDTEPEAV GTGISKDEYI KVAMKDNEWG
110 120 130 140 150
GSLEASMLSK HLQTTIILWV VNSTEQVTAA IKFGPGRVST ALNLMHVGRT
160 170 180 190 200
HFDALRIIEQ LENNQPQDRN RLDIADRIAA AEVYVRQSIE DNLQEDEFFD
210 220 230 240 250
YAREDEISED VSAPGGSREA TELKKKAILL NKTVKRGENI PIRVGRVLDC
260 270 280 290 300
LFSCKIAVSL DEGLLYLRPE TRESEATSIS LRQLGHKLLT RDRHIKMEYA
310 320 330 340 350
RSKLYVTRDL IDHLDIGGLL RSSFPGLGLE RYIQLLHSEL VLDLVTVVLA
360 370 380 390 400
VLLSTFLYGS NNKNKKQFIT NCLLNTKLSG KRVFKALSKL TGQMLYRTPK
410 420 430 440 450
RAVSIVSQEL YGKLMLKVKN NLEGMGPISM LALRNLNFDN MQLQDYLEML
460 470 480 490 500
SEMSKIDNSD VEYTHREISD LHTLVERLSK LQKSQDVNEL KLWFKEEVLT
510 520 530 540 550
KRSQRSVGNA FEFLINDYFK KKDIMKFVST SGKASSTGNI GNVLSYAHNL
560 570 580 590 600
YLSKESLRMT SEDVTQLLIE IRKLHKLQGD LSIEPVAIIC DKLEDQFRKL
610 620 630 640 650
FRELPEECSS ECQTLFNDIR NSPSHSVAWK HALRLKGTAY EGMFAKQYGW
660 670 680 690 700
SYISEDIKPS LTMIVQTLFP ESFEAFLDRT QLHPEFRDLT PDYALTQKIF
710 720 730 740 750
FPRNTIPRTE NRQLAIDVSL EGSVEAVPIV EKRMFPLPEV PIGEANSISR
760 770 780 790 800
VMNIFKEKRE ESMQKKLEHD RQAEANRLKS AGLSASKAEQ EVCNSAQDRK
810 820 830 840 850
EEKERTTEPA GKQQRTEDLV VIEGNQDEGD SDPQKKVDEK TVPGESKQHS
860 870 880 890 900
KSSGSSSTNQ MSQKVVDVPS VEDSSDQAPG DFPDYGYYFK RIVMDESGTV
910 920 930 940 950
LTEEAQLEKR QLLFIEVGYQ TDVDGKITTD YKKWKDILRL LELLNIKCSF
960 970 980 990 1000
IACADCSSTP SNNWWISEDK VRLLKNSISH LFSKLTQNSP ADVTDIVVGS
1010 1020 1030 1040 1050
ISTQKVRSYL KSGTATKTPI SLKDVQETWS KMKDYIVNRP TGISLNKELV
1060 1070 1080 1090 1100
GALYQGLVEG AIISKEGTVN LIQMLKDKQE RITDEFERTK LKHEVNEDVK
1110 1120 1130 1140 1150
TSEKLLLGWL MEDLKGCRCM GCLTKIKELS ESMSVNQDRL EYLSTNCQTK
1160 1170 1180 1190 1200
SHCTECHPRS LEYRNISNVD NRVPSMQRVS HSRNEGFEDT NETLTELDRL
1210 1220 1230 1240 1250
VRLTLPGKTE KERRVKRNVE GLIRFMMQQS SLDCIKLPSG QIIAHRCSKK
1260 1270 1280 1290 1300
FKNSSEAEEK CNERFERLMK ELSEQKLKPY SDHVRKTITS SLKKTDKQAG
1310 1320 1330 1340 1350
SKCAVPRLWL ETLIRDLRVP TKDEEILLNI RTSMQSKTNF IRNNDKLIIR
1360 1370 1380 1390 1400
SNKEIADYLE TKRKNLLSEK ASDKIFSSDC ILFKEVIAEA LRRYYSTPYE
1410 1420 1430 1440 1450
GVPETIVKLI NFLCTFGWFQ EVVLYSKICE TFLRCCTEFS RSGIKLVKVR
1460 1470 1480 1490 1500
HCDTNLSIKL PSNKKENMLC CLYDKNMSLL KGPFFLNRRQ AILGSAYPYI
1510 1520 1530 1540 1550
LITLYIQVLQ QHRCLEVLNS VNDRVVGNIN TCTSNLLNTV KAELTLVNSG
1560 1570 1580 1590 1600
LFEKAYECRT EQCRLGGNFL NRSSRDHFIS TVSGLNVVYG ALIKDNLLAN
1610 1620 1630 1640 1650
SQPQNKQLQM LRFGMLCGLS RLSSALELGK KFSTSCRRIE DNIMRLYLQS
1660 1670 1680 1690 1700
TIYSANRDVS QNVQNWKMKD LCPDITIPCF SVYGLFVNSD RQRIFDIYNV
1710 1720 1730 1740 1750
HIYNKEMDNF DEGCITVLEE TAERHMLWEL DLLRSLEGDT RDVRAARLLL
1760 1770 1780 1790 1800
GCPNIRKATD KDGNRLMKKG ITDDWREEAG SDSSSISGRR SYASSGTRVK
1810 1820 1830 1840 1850
SMFGKYNSSQ KPFELKPGLE VVNDPLHDYK QAVQDSFCYS EYTPNTESVL
1860 1870 1880 1890 1900
KDCIHIIRTN PSHTMGSYEL IQAVTENARR KYPPENIERA RKDPKNWVSI
1910 1920 1930 1940 1950
SEVTETTSIV SQPRTHFMLK DCYKVLLGTE NKKIVKMLRG KLKKLGAMRT
1960 1970 1980 1990 2000
DIEIGKKDCL DLLTTVDGLS EEQCKNIVNG IFEPSKLSFY HWKDLLKKEL
2010 2020 2030 2040 2050
SEVLLTDDGN YIYCWLKTLS SMVKHSLKKD LRFMTGKNSL DIKPEMFTDE
2060 2070 2080 2090 2100
EYSALNIMKL ELLGEHTDGI QGKTDFLLSS WKKCALKPKE GQSILNVGLN
2110 2120 2130 2140 2150
SLAALHDELY DIRLQHLELT RIKKENPTVS FTKEEILVKR LEKGFLNKYK
2160 2170 2180 2190 2200
KEVMEAVNLI FYCCLTAPWC LHYKSLEAYL VRHPEILETE CIKENDIPLL
2210 2220 2230 2240 2250
DLTVTSLIRS LIDDIEGESS FNDSSDIKVR FAVKYLITLF TANGEPFSLS
2260 2270 2280 2290 2300
LNDGGLNDDL QLTTDEKLLY QTKKVFAKLG LSGNNYDFIW TLQMIANSNF
2310 2320 2330 2340 2350
NVCKRLTGRT TGERLPRSVR SKVIYEMVKL VGETGMAILQ QLAFSQALNY
2360 2370 2380 2390 2400
DHRFYAVLAP KAQLGGSRDL LVQETGTKVI HATTEMFSRN LLKTTSDDGL
2410 2420 2430 2440 2450
TNPHLKETRL NIGLDMLSTA RALDGKQVSD DSNLLNFFKT VCISGDNTKW
2460 2470 2480 2490 2500
GPIHCCSFFS GMMQQLLKDV QDWSSFYKLT FIKNLCRQIE IPAPSIRKIL
2510 2520 2530 2540 2550
NVLRFKLSDK GGVEKLSEEA IRSELINNLA EWEGNDTVKF LITTYISKGI
2560 2570 2580 2590 2600
MAMNSYNHMG QGIHHATSSL LTSMMAETFE ELAVDYMKKH FPGLTVNVDH
2610 2620 2630 2640 2650
AGSSDDYAKC IIVSGLVSKD MYKRYDGVFW RHMCRLKNFL AAVRRCCQMK
2660 2670 2680 2690 2700
DSAKTLVGDC FLEFYSEFMM GNRVTPAVIK FIFTGLINSS VTSPQSLVQA
2710 2720 2730 2740 2750
CHVSSQQGMY NSVPLVTNAA FTILRQQIFY NHVEDFIRRY GLITLGAVSP
2760 2770 2780 2790 2800
FGRLFLPRFS GLVSSSVALE DSETISKAAA EINSNDIFFN TSSLSNLDKL
2810 2820 2830 2840 2850
EQSPDSSGLD DDSVVSTTTV ESSDSKGSSS SFTFDLNRPL SETEVKFLKL
2860 2870 2880 2890 2900
LRELTSTTAC EMLQEKINTL YNDSREGPLD RHNILQNCRL SESCDWLLDG
2910 2920 2930 2940 2950
KKRGLLELSR RMSCLLNVLI AGYYRSFGSE GTEKQVKASW SRDDNRVIED
2960 2970 2980 2990 3000
PMIQLIPEKL RRELERLGLS RMEVDELMPA VGPDESLSQL VAKKLISLNV
3010 3020 3030 3040 3050
STEEYSAEVS RLKQTLTARN VLHGLAGGIK ELSLPIYTIF MKPYFFKDNV
3060 3070 3080 3090 3100
FLDLEDRWSS RHSTNYRDST GKMLTGKVVT KFTHWLDTFL SCVVSANRSQ
3110 3120 3130 3140 3150
EIKECSLFNP NLRCVNIMVK GNGIKELSYI RSHLSVLSVE FENLNLQFSD
3160 3170 3180 3190 3200
VNRQKLKIVE SRPPECELEA NKAVIIKSKL FSAVEHVRLS NNPAVVMGYL
3210 3220 3230 3240 3250
LEESSISEVK PTKVDFSNLL KHRFKLMQFF PSVFTLLRSL QSESKELEKL
3260 3270 3280 3290 3300
GEPVDMHQVS KYANHLTLLC RMIQQSKPSL TVFYMLKGSQ MNTEPTVSEL
3310 3320 3330 3340 3350
VSYGIKEGRF LKLPEIGLDA STYSVRYWKI LHCISAIGEL PLSSEDKTSL
3360 3370 3380 3390 3400
LISFLNWKVT SDCVDDCCPL EKYDKAIVSE FSGQVLINTL ASELSSVRKD
3410 3420 3430 3440 3450
QEREGLTDLI DYINSPSELL KKKPYLGTTC RFQCWGEGAK SGKFTYSSRT
3460 3470 3480 3490 3500
GEAIGIFVAG KLHIHLTSDS PGLLCEVERQ VLSWLGKRRT DVLTKEQHQF
3510 3520 3530 3540 3550
FLDFLPNLSE VVQKNRDGAI LGVTIDSTNV RMLKYVPPKR NTPVIKIKKQ
3560 3570 3580 3590 3600
ILTVKKQTTL DVESEPRIVW GHGQLSIVYD ECETETTYHE NLIKVKKLVD
3610 3620 3630 3640 3650
LASGTTDKLP TAIFSDTRIT LARVKFKTEL LLNSLCLLHC FLKHTSQDAI
3660 3670 3680 3690 3700
QEVESKCNVL ERYLRSGGVQ FRPMSESLDK KVTKLPLQCQ SDKDVDKEIN
3710 3720 3730 3740 3750
FCEDLTRVFS NENVPLSSWS EVQSYIEEVG FGNVLVHIEK NPTRSDLIWR
3760 3770 3780 3790 3800
FSIDSISGNF GPIKDIRTLV TYMSTETVPK FLLPFLLFEE QLKHLIAGCV
3810 3820 3830 3840 3850
ELRDALNSSG INDREIAIVA LFTCFYYQSD SVKRQGPVCS ISSFCSLIGD
3860 3870 3880 3890 3900
DLLPLDNRLQ ARVLPEQDNV KLHFKLNLTT DSALGKKDKA IQAKKIISRY
3910 3920 3930 3940 3950
LRLIFTEDDM DLKRLKSDAT KVKLSSEKEC EFLEFCLHSD LSYALNYRVL
3960 3970 3980 3990 4000
LEHLIDLEDR AKKTACVLIE EFILMLTGRL MISSTIDSDS KRTLEDDALC
4010 4020 4030
LEDLLDSDNE ASSSKSDNEE QIALQTGKFN FNWDSD
Length:4,036
Mass (Da):459,392
Last modified:November 1, 1996 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE2EDF0B4358E31BD
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
U15018 Genomic RNA Translation: AAB18834.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U15018 Genomic RNA Translation: AAB18834.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

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RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4HXDX-ray2.85B/D2-169[»]
SMRiQ66431
ModBaseiSearch...
PDBe-KBiSearch...

Protein family/group databases

MEROPSiC87.001

Proteomic databases

PRIDEiQ66431

Family and domain databases

InterProiView protein in InterPro
IPR003323 OTU_dom
IPR007099 RNA-dir_pol_NSvirus
IPR007322 RNA_pol_bunyavir
PfamiView protein in Pfam
PF04196 Bunya_RdRp, 1 hit
PF02338 OTU, 1 hit
PROSITEiView protein in PROSITE
PS50802 OTU, 1 hit
PS50525 RDRP_SSRNA_NEG_SEG, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiL_DUGBA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q66431
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: November 1, 1996
Last modified: December 11, 2019
This is version 94 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
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