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Protein

Peptidyl-tRNA hydrolase

Gene

pth

Organism
Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / NBRC 12200 / NCIMB 9375 / NRRL NRS-1264 / Gibson 46)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.UniRule annotation

Catalytic activityi

N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Peptidyl-tRNA hydrolaseUniRule annotation (EC:3.1.1.29UniRule annotation)
Short name:
PTHUniRule annotation
Gene namesi
Name:pthUniRule annotation
Synonyms:spoVC
Ordered Locus Names:BLi00066, BL00517
OrganismiBacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / NBRC 12200 / NCIMB 9375 / NRRL NRS-1264 / Gibson 46)
Taxonomic identifieri279010 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000000606 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001876901 – 188Peptidyl-tRNA hydrolaseAdd BLAST188

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi279010.BLi00066

Structurei

3D structure databases

ProteinModelPortaliQ65PG8
SMRiQ65PG8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PTH family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0193 LUCA
HOGENOMiHOG000004797
KOiK01056
OMAiRYAHTRH

Family and domain databases

CDDicd00462 PTH, 1 hit
Gene3Di3.40.50.1470, 1 hit
HAMAPiMF_00083 Pept_tRNA_hydro_bact, 1 hit
InterProiView protein in InterPro
IPR001328 Pept_tRNA_hydro
IPR018171 Pept_tRNA_hydro_CS
IPR036416 Pept_tRNA_hydro_sf
PANTHERiPTHR17224 PTHR17224, 1 hit
PfamiView protein in Pfam
PF01195 Pept_tRNA_hydro, 1 hit
SUPFAMiSSF53178 SSF53178, 1 hit
TIGRFAMsiTIGR00447 pth, 1 hit
PROSITEiView protein in PROSITE
PS01195 PEPT_TRNA_HYDROL_1, 1 hit
PS01196 PEPT_TRNA_HYDROL_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q65PG8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLVFAGLGNP GKTYENTRHN VGFMTIDELS KEWNIPLDKT KFNGQYGIGF
60 70 80 90 100
VSGKKVLLVK PLTYMNLSGE CLRPLLDYYE IPVDNLKVIY DDLDLPTGRI
110 120 130 140 150
RLRTKGSAGG HNGIKSTIQH LGTSEFNRIR IGIGRPVNGM KVVDYVLGAF
160 170 180
TDEEEPAIKE AVRQSAKACE ASLEKPFLEV MNEFNAKV
Length:188
Mass (Da):20,924
Last modified:October 25, 2004 - v1
Checksum:iCFB79D8B0A971827
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017333 Genomic DNA Translation: AAU39046.1
CP000002 Genomic DNA Translation: AAU21701.1
RefSeqiWP_003178208.1, NC_006322.1

Genome annotation databases

EnsemblBacteriaiAAU21701; AAU21701; BL00517
AAU39046; AAU39046; BLi00066
GeneIDi3027753
KEGGibld:BLi00066
bli:BL00517
PATRICifig|279010.13.peg.59

Similar proteinsi

Entry informationi

Entry nameiPTH_BACLD
AccessioniPrimary (citable) accession number: Q65PG8
Secondary accession number(s): Q62ZV7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 21, 2005
Last sequence update: October 25, 2004
Last modified: June 20, 2018
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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